Detalhe da pesquisa
1.
Pharmacokinetics, metabolism, and excretion of (14)C-labeled belinostat in patients with recurrent or progressive malignancies.
Invest New Drugs
; 34(2): 193-201, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26769244
2.
The NAD biosynthesis inhibitor APO866 has potent antitumor activity against hematologic malignancies.
Blood
; 113(14): 3276-86, 2009 Apr 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-19196867
3.
Evaluation of the topoisomerase II-inactive bisdioxopiperazine ICRF-161 as a protectant against doxorubicin-induced cardiomyopathy.
Toxicology
; 255(1-2): 72-9, 2009 Jan 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-19010377
4.
A phase 1 pharmacokinetic and pharmacodynamic study of the histone deacetylase inhibitor belinostat in patients with advanced solid tumors.
Clin Cancer Res
; 14(3): 804-10, 2008 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18245542
5.
Plasma and cerebrospinal fluid pharmacokinetics of the histone deacetylase inhibitor, belinostat (PXD101), in non-human primates.
Cancer Chemother Pharmacol
; 62(3): 433-7, 2008 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-17960383
6.
Determination of oxytetracycline and its degradation products by high-performance liquid chromatography-tandem mass spectrometry in manure-containing anaerobic test systems.
J Chromatogr B Analyt Technol Biomed Life Sci
; 783(1): 11-23, 2003 Jan 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-12450520
7.
Chemical reactivity of the naproxen acyl glucuronide and the naproxen coenzyme A thioester towards bionucleophiles.
J Pharm Biomed Anal
; 29(1-2): 7-15, 2002 Jun 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-12062660
8.
Isolation, structural elucidation and in vitro activity of 2-acetyl-2-decarboxamido-oxytetracycline against environmental relevant bacteria, including tetracycline-resistant bacteria.
J Pharm Biomed Anal
; 34(3): 559-67, 2004 Feb 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-15127812
9.
Quantitative analysis of oxytetracycline and its impurities by LC-MS-MS.
J Pharm Biomed Anal
; 34(2): 325-32, 2004 Feb 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-15013146
10.
Determination of the distribution coefficient (log Kd) of oxytetracycline, tylosin A, olaquindox and metronidazole in manure.
Chemosphere
; 48(3): 351-61, 2002 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-12146624
11.
Characterisation of the abiotic degradation pathways of oxytetracyclines in soil interstitial water using LC-MS-MS.
Chemosphere
; 50(10): 1331-42, 2003 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-12586164
12.
LC-MS/MS assay for the quantitation of the HDAC inhibitor belinostat and five major metabolites in human plasma.
J Pharm Biomed Anal
; 81-82: 89-98, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23644904
13.
Nicotinamide phosphoribosyltransferase inhibitors, design, preparation, and structure-activity relationship.
J Med Chem
; 56(22): 9071-88, 2013 Nov 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-24164086
14.
Synthesis and antitumor effect in vitro and in vivo of substituted 1,3-dihydroindole-2-ones.
J Med Chem
; 53(19): 7140-5, 2010 Oct 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-20845961
15.
Identification of predictive biomarkers for the histone deacetylase inhibitor belinostat in a panel of human cancer cell lines.
Cancer Biomark
; 4(2): 101-9, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-18503161
16.
Method optimisation with the use of uncertainty budgets.
Analyst
; 127(1): 140-3, 2002 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-11827381
17.
Identification of the amino acids of human serum albumin involved in the reaction with the naproxen acyl coenzyme A thioester using liquid chromatography combined with fluorescence and mass spectrometric detection.
Anal Biochem
; 312(2): 148-56, 2003 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-12531199
18.
Stereospecific pH-dependent degradation kinetics of R- and S-naproxen-beta-l-O-acyl-glucuronide.
Chirality
; 14(4): 305-12, 2002 May 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-11968070