RESUMO
The most dangerous disease in recent decades is lung cancer. The most accurate method of cancer diagnosis, according to research, is through the use of histopathological images that are acquired by a biopsy. Deep learning techniques have achieved success in bioinformatics, particularly medical imaging. In this paper, we present an innovative method for rapidly identifying and classifying histopathology images of lung tissues by combining a newly proposed Convolutional Neural Networks (CNN) model with a few total parameters and the enhanced Light Gradient Boosting Model (LightGBM) classifier. After the images have been pre-processed in this study, the proposed CNN technique is provided for feature extraction. Then, the LightGBM model with multiple threads has been used for lung tissue classification. The simulation result, applied to the LC25000 dataset, demonstrated that the novel technique successfully classifies lung tissue with 99.6% accuracy and sensitivity. Furthermore, the proposed CNN model has achieved the lowest training parameters of only one million parameters, and it has also achieved the shortest processing time of just one second throughout the feature extraction process. When this result is compared with the most recent state-of-the-art approaches, the suggested approach has increased effectiveness in the areas of both disease classification accuracy and processing time.
RESUMO
In the last few years, it was proposed to deliver drugs using Nano-robots for treating cancer. This paper compares between two recent and efficient algorithms for delivering Nano-robots to cancer area. These algorithms are Jaya algorithm and Directed Particle Swarm Optimization (DPSO) algorithm. In this paper, we also propose a new hybrid algorithm that combines Jaya and DPSO to speed up the process of Nano-robots delivery. The proposed algorithm is called Directed Jaya (DJaya) algorithm. Experiments have proved that the efficiency of DJaya is higher than both Jaya and DPSO. We show experimentally that DJaya starts delivering Nano-robots earlier than DPSO to facilitate the initiation of the drug release. Also, DJaya finishes delivering Nano-robots earlier than Jaya to complete the drug dose. In addition to this, DJaya groups the Nano-robots together in the target area like DPSO to speed up the drug release process. We finally propose a new strategy for destroying cancer cells efficiently with relatively small number of Nano-robots. This strategy can save 40% of Nano-robots.
Assuntos
Algoritmos , Nanotecnologia , Neoplasias/terapia , Robótica , Simulação por Computador , HumanosRESUMO
The past twenty years have ignited a new spark in the research of Electroencephalogram (EEG), which was pursued to develop innovative Brain Computer Interfaces (BCIs) in order to help severely disabled people live a better life with a high degree of independence. Current BCIs are more theoretical than practical and are suffering from numerous challenges. New trends of research propose combining EEG to other simple and efficient bioelectric inputs such as Electro-oculography (EOG) resulting from eye movements, to produce more practical and robust Hybrid Brain Computer Interface systems (hBCI) or Brain/Neuronal Computer Interface (BNCI). Working towards this purpose, existing research in EOG based Human Computer Interaction (HCI) applications, must be organized and surveyed in order to develop a vision on the potential benefits of combining both input modalities and give rise to new designs that maximize these benefits. Our aim is to support and inspire the design of new hBCI systems based on both EEG and EOG signals, in doing so; first the current EOG based HCI systems were surveyed with a particular focus on EOG based systems for communication using virtual keyboard. Then, a survey of the current EEG-EOG virtual keyboard was performed highlighting the design protocols employed. We concluded with a discussion of the potential advantages of combining both systems with recommendations to give deep insight for future design issues for all EEG-EOG hBCI systems. Finally, a general architecture was proposed for a new EEG-EOG hBCI system. The proposed hybrid system completely alters the traditional view of the eye movement features present in EEG signal as artifacts that should be removed; instead EOG traces are extracted from EEG in our proposed hybrid architecture and are considered as an additional input modality sharing control according to the chosen design protocol.