Detalhe da pesquisa
1.
Epigenetic balance ensures mechanistic control of MLL amplification and rearrangement.
Cell
; 186(21): 4528-4545.e18, 2023 10 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37788669
2.
DNA polymerase θ protects leukemia cells from metabolically induced DNA damage.
Blood
; 141(19): 2372-2389, 2023 05 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36580665
3.
Enhanced Accumulation of Betulinic Acid in Transgenic Hairy Roots of Senna obtusifolia Growing in the Sprinkle Bioreactor and Evaluation of Their Biological Properties in Various Biological Models.
Chem Biodivers
; 18(8): e2100455, 2021 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-34185351
4.
Tyrosine kinase inhibitor-induced defects in DNA repair sensitize FLT3(ITD)-positive leukemia cells to PARP1 inhibitors.
Blood
; 132(1): 67-77, 2018 07 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29784639
5.
(1-4)-Thiodisaccharides as anticancer agents. Part 5. Evaluation of anticancer activity and investigation of mechanism of action.
Bioorg Med Chem Lett
; 30(4): 126904, 2020 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31882294
6.
Novel allosteric PARP1 inhibitors for the treatment of BRCA-deficient leukemia.
Med Chem Res
; 29(6): 962-978, 2020 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-33071527
7.
The Extract of Leonurus sibiricus Transgenic Roots with AtPAP1 Transcriptional Factor Induces Apoptosis via DNA Damage and Down Regulation of Selected Epigenetic Factors in Human Cancer Cells.
Neurochem Res
; 43(7): 1363-1370, 2018 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-29786770
8.
Induction of apoptosis in human glioma cell lines of various grades through the ROS-mediated mitochondrial pathway and caspase activation by Rhaponticum carthamoides transformed root extract.
Mol Cell Biochem
; 445(1-2): 89-97, 2018 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-29238899
9.
A preliminary study of apoptosis induction in glioma cells via alteration of the Bax/Bcl-2-p53 axis by transformed and non-transformed root extracts of Leonurus sibiricus L.
Tumour Biol
; 37(7): 8753-64, 2016 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-26743778
10.
Associations between DNA Damage, DNA Base Excision Repair Gene Variability and Alzheimer's Disease Risk.
Dement Geriatr Cogn Disord
; 41(3-4): 152-71, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27011006
11.
Association between Single-Nucleotide Polymorphisms of the hOGG1,NEIL1,APEX1, FEN1,LIG1, and LIG3 Genes and Alzheimer's Disease Risk.
Neuropsychobiology
; 73(2): 98-107, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27010693
12.
Single-Nucleotide Polymorphisms of Genes Involved in Repair of Oxidative DNA Damage and the Risk of Recurrent Depressive Disorder.
Med Sci Monit
; 22: 4455-4474, 2016 Nov 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-27866211
13.
Genotoxicity and cytotoxicity of ZnO and Al2O3 nanoparticles.
Toxicol Mech Methods
; 25(3): 176-83, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25578534
14.
[Synthetic lethality as a functional tool in basic research and in anticancer therapy]. / Syntetyczna letalnosc jako funkcjonalne narzedzie w badaniach podstawowych oraz w terapii przeciwnowotworowej.
Postepy Hig Med Dosw (Online)
; 68: 1091-103, 2014 Sep 03.
Artigo
em Polonês
| MEDLINE | ID: mdl-25228518
15.
Simultaneous Targeting of DNA Polymerase Theta and PARP1 or RAD52 Triggers Dual Synthetic Lethality in Homologous Recombination-Deficient Leukemia Cells.
Mol Cancer Res
; 21(10): 1017-1022, 2023 10 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37358557
16.
4'-Ethynyl-2'-Deoxycytidine (EdC) Preferentially Targets Lymphoma and Leukemia Subtypes by Inducing Replicative Stress.
Mol Cancer Ther
; 2023 Dec 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38064712
17.
Relationship between Oxidative Stress and Imatinib Resistance in Model Chronic Myeloid Leukemia Cells.
Biomolecules
; 11(4)2021 04 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-33924068
18.
An Extract of Transgenic Senna obtusifolia L. Hairy Roots with Overexpression of PgSS1 Gene in Combination with Chemotherapeutic Agent Induces Apoptosis in the Leukemia Cell Line.
Biomolecules
; 10(4)2020 03 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-32230928
19.
Insight the Biological Activities of Selected Abietane Diterpenes Isolated from Plectranthus spp.
Biomolecules
; 10(2)2020 01 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-32012853
20.
DNA Double Strand Break Repair - Related Synthetic Lethality.
Curr Med Chem
; 26(8): 1446-1482, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-29421999