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1.
J Oral Maxillofac Surg ; 74(11): 2329.e1-2329.e5, 2016 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-27444102

RESUMO

Osteoma is a benign, mesenchymal, slow-growing, osteogenic tumor commonly occurring in the craniofacial bones and is characterized by the proliferation of compact or cancellous bone. Solitary osteomas can be classified as peripheral (parosteal, periosteal, or exophytic) when arising from the periosteum or central (endosteal) when arising from soft tissue. Peripheral osteoma occurs most frequently in the paranasal sinuses. Other locations include the orbital wall, temporal bone, pterygoid processes, external ear canal, and, rarely, the mandible. Osteomas in the oromandibular region often appear in the jaw in the canine fossa, hard palate, and maxillary sinus and in the lower jaw in the inner mandible and outer circumference and lingual side of the molar region. At radiologic imaging, a peripheral osteoma of the mandible appears as a well-circumscribed, round to oval, mushroom-like radiopaque mass with distinct borders. Computed tomography is the best imaging modality for determining the location and actual extension of the lesion. Parapharyngeal space tumors are rare tumors of the head and neck region. Benign tumors of the parapharyngeal space are more common than malignant tumors. A foreign body sensation in the pharynx, difficulty with deglutition, and hoarseness are symptoms generally related to the position of the tumor. Upper airway obstruction, painful throat, unilateral tinnitus, trismus, dysarthria, glossopharyngeal neuralgia, and cranial nerve palsies are other reported symptoms. This report presents the case of a huge osteoma of the left mandibular condyle extending to the parapharyngeal space.


Assuntos
Neoplasias Mandibulares/cirurgia , Cirurgia Endoscópica por Orifício Natural/métodos , Osteoma/cirurgia , Feminino , Humanos , Neoplasias Mandibulares/diagnóstico , Neoplasias Mandibulares/patologia , Pessoa de Meia-Idade , Invasividade Neoplásica , Osteoma/diagnóstico , Osteoma/patologia , Faringe
2.
Eur Arch Otorhinolaryngol ; 271(12): 3147-53, 2014 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-24196347

RESUMO

In this study, we evaluated clinical results and health-related quality of life in our otoplasty patients in whom we used cartilage resection method (CRM) and suturing method (SM). A total of 132 ears of 77 patients (36 males, 41 females; mean age 14.6 ± 6.4) between January 2006 and February 2013 were included in this study. Patients were divided into two groups according to the type of surgery performed: Group 1 was the cartilage resection group (CRG) and Group 2 was the suturing group (SG). CRM was performed on 64 ears of 37 patients (unilateral in 10 cases and bilateral in 27 cases), and SM was performed on 68 ears of 40 patients (unilateral in 12 cases and bilateral in 28 cases). The parameters of the groups, including operation time, measurements of the auriculocephalic distances, complication rates, postoperative satisfaction rates, and health-related quality of life were compared. Mean operation time was 53.7 ± 7.8 min in the CRG and 44.9 ± 4.2 min in the SG (P ≤ 0.05). Mean postoperative auriculocephalic measurements were similar in both groups. The complications were more frequent in the CRG (10/37 patients, 27.02 %) than in the SG (3/40 patients, 7.54 %) with statistically significant difference (P < 0.05). Three months after the surgery, visual analog scale increased from 25 (preoperatively) to 70 in the CRG and from 30 to 90 in the SG, with a statistically significant difference (P < 0.05). Patients' health-related quality of life showed a statistically significant increase after the operation in both groups (P < 0.05). CRM and SM are effective treatment methods with high success rates for patients with prominent ears. In the selected cases, SM seems to represent a better option for otoplasty than CRM because clinical results, cosmetic outcomes, patient satisfaction, and health-related quality of life scores were better than CRM.


Assuntos
Deformidades Adquiridas da Orelha , Orelha Externa , Procedimentos Cirúrgicos Otológicos , Procedimentos de Cirurgia Plástica , Qualidade de Vida , Adolescente , Cartilagem/cirurgia , Criança , Deformidades Adquiridas da Orelha/diagnóstico , Deformidades Adquiridas da Orelha/psicologia , Deformidades Adquiridas da Orelha/cirurgia , Orelha Externa/patologia , Orelha Externa/cirurgia , Feminino , Humanos , Masculino , Duração da Cirurgia , Procedimentos Cirúrgicos Otológicos/efeitos adversos , Procedimentos Cirúrgicos Otológicos/métodos , Procedimentos Cirúrgicos Otológicos/psicologia , Satisfação do Paciente , Complicações Pós-Operatórias/diagnóstico , Procedimentos de Cirurgia Plástica/efeitos adversos , Procedimentos de Cirurgia Plástica/métodos , Procedimentos de Cirurgia Plástica/psicologia , Técnicas de Sutura , Resultado do Tratamento , Adulto Jovem
3.
Eur Arch Otorhinolaryngol ; 271(7): 1885-9, 2014 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-23995707

RESUMO

In this study, we evaluated our otoplasty surgery results in patients with prominent ears. A total of 76 ears in 42 patients (20 male, 22 female; mean age 14; range 6-34 years) who underwent otoplasty surgery under general anesthesia between April 2005 and February 2012 were evaluated retrospectively. Of the 76 surgical cases, while 65 were operated on for the first time (primary), 6 had had previous unsuccessful surgical interventions at other institutes (secondary) and 5 were our own revision surgery cases. Of the primary cases; 11 had unilateral and 27 had bilateral surgery. Postoperative follow-ups were performed at week one, months one, three and six and at 1 year. While 60 of the 65 primary surgeries and all 6 of the secondary surgeries had successful results, 5 cases required revision surgery. The revision otoplasty surgeries were found to be successful in all patients on follow-up visits. Otoplasty surgery is an effective treatment method with high success rates for patients with prominent ears.


Assuntos
Orelha Externa/anormalidades , Orelha Externa/cirurgia , Procedimentos de Cirurgia Plástica , Técnicas de Sutura , Adolescente , Adulto , Criança , Feminino , Humanos , Masculino , Satisfação do Paciente , Reoperação , Estudos Retrospectivos , Resultado do Tratamento , Adulto Jovem
4.
J Craniofac Surg ; 25(2): e138-40, 2014.
Artigo em Inglês | MEDLINE | ID: mdl-24621753

RESUMO

Fungus ball in the concha bullosa is an extremely rare disease. We described a case of the fungus ball in the concha bullosa in a 22-year-old woman. Preoperative diagnosis was based on nasal endoscopy and computed tomography scanning. The patient was endoscopically operated on. The examination of the removed material was reported as fungal infection. This case was found worth writing because of the location of the concha bullosa and its rare occurrence in this location.


Assuntos
Dor Ocular/etiologia , Micetoma/diagnóstico por imagem , Micetoma/cirurgia , Doenças Nasais/diagnóstico por imagem , Doenças Nasais/cirurgia , Órbita , Tomografia Computadorizada por Raios X , Conchas Nasais/diagnóstico por imagem , Conchas Nasais/cirurgia , Diagnóstico Diferencial , Endoscopia , Feminino , Humanos , Micetoma/microbiologia , Micologia/métodos , Conchas Nasais/microbiologia , Turquia , Adulto Jovem
5.
J Craniofac Surg ; 25(2): e168-70, 2014.
Artigo em Inglês | MEDLINE | ID: mdl-24621760

RESUMO

There are many causes of conductive hearing loss. Otoplasty is a commonly performed cosmetic surgery to correction for prominent ear. We discussed an unusual cause of conductive hearing loss, bilateral complete meatal obstruction following otoplasty, in this article. This complication was probably due to unsuitable placement of the Furnas sutures. In the literature, as a cause of conductive hearing loss, unilateral complete meatal obstruction has been described rarely, but bilateral complete obstruction has not been defined. Hearing loss recovered completely after revision surgery. Correct diagnosis, accurate preoperative or perioperative examination, choice of the proper technique and surgeon experience are essential for avoiding inadequate results or complications of otoplasty. The surgeon should be aware of the cartilage elasticity and suture techniques to avoid this complication.


Assuntos
Cartilagem da Orelha/cirurgia , Deformidades Adquiridas da Orelha/etiologia , Orelha Externa/cirurgia , Perda Auditiva Condutiva/etiologia , Procedimentos Cirúrgicos Otológicos/efeitos adversos , Procedimentos de Cirurgia Plástica/efeitos adversos , Técnicas de Sutura/efeitos adversos , Adolescente , Constrição Patológica/etiologia , Meato Acústico Externo , Cartilagem da Orelha/anormalidades , Deformidades Adquiridas da Orelha/cirurgia , Humanos , Masculino , Procedimentos de Cirurgia Plástica/métodos , Reoperação , Cirurgia Plástica/efeitos adversos
6.
J Craniofac Surg ; 25(5): 1779-81, 2014 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-25098571

RESUMO

Antrochoanal polyp is a benign polypoid lesion orginating from the maxillary sinus antrum and extending to the choana. Our aim was to assess the clinical presentation and associated rhinological findings of antrochoanal polyp patients and to evaluate results of 2 surgical treatments termed endoscopic sinus surgery (ESS) and ESS plus mini-Caldwell operation. The study included 46 patients. Factors such as patient age, sex, history of chronic sinusitis, allergic rhinitis, septal deviations, chonca bullosa, turbinate hypertrophy, and the origin of the polyp were assessed. We also evaluated ESS and ESS plus mini-Caldwell surgical procedures for recurrences, synechia, bleeding, and ostium stenosis. Overall, there were 27 men and 19 women. The ESS approach was used in 26 cases, and 20 cases had combined ESS and mini-Caldwell procedures. The statistical significant difference between the 2 groups was only recurrence (P < 0.05). In the ESS group, bleeding, synechia, and ostium stenosis were seen more than in the ESS + mini-Caldwell group, but there was no significant difference between the 2 groups in bleeding, synechia, and ostium stenosis (P > 0.05). We thought that lower rate of recurrence found in ESS + Caldwell group in this study was associated with better visualization of the maxillary sinus walls and, therefore, easier resection of the remnant polyp. We concluded that higher incidences of bleeding and synechia were related to the mucosal damage occurring in the septum and the inferior concha due to excessive manipulation of endoscope and surgical instruments.


Assuntos
Endoscopia/métodos , Seio Maxilar/cirurgia , Pólipos Nasais/cirurgia , Procedimentos Cirúrgicos Otorrinolaringológicos/métodos , Doenças dos Seios Paranasais/cirurgia , Adolescente , Adulto , Criança , Doença Crônica , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Seios Paranasais/patologia , Recidiva , Estudos Retrospectivos , Adulto Jovem
7.
Kulak Burun Bogaz Ihtis Derg ; 24(5): 299-302, 2014.
Artigo em Turco | MEDLINE | ID: mdl-25513876

RESUMO

Desmoid tumor is a benign tumor which originates from musculoaponeurotic system, can reach greater sizes with local invasion among facial plans, and cause severe deformities, morbidity and even mortality by compression of adjacent structures. These tumors are rarely seen in the head and neck region. The treatment of advanced desmoid tumors of head and neck region is surgery and radiotherapy. In this paper, we present -to the best of our knowledge- the greatest desmoid tumor case of the head and neck region in the literature.


Assuntos
Fibromatose Agressiva/diagnóstico , Neoplasias de Cabeça e Pescoço/diagnóstico , Terapia Combinada , Fibromatose Agressiva/diagnóstico por imagem , Fibromatose Agressiva/radioterapia , Fibromatose Agressiva/cirurgia , Neoplasias de Cabeça e Pescoço/diagnóstico por imagem , Neoplasias de Cabeça e Pescoço/radioterapia , Neoplasias de Cabeça e Pescoço/cirurgia , Humanos , Masculino , Radiografia , Adulto Jovem
8.
J Craniofac Surg ; 24(3): e270-1, 2013 May.
Artigo em Inglês | MEDLINE | ID: mdl-23714987

RESUMO

Tufted angiomas may occur in the head and neck region, but the external auditory canal is a previously undefined localization. There are only 19 cases of hemangiomas reported in this unique localization. However, this case is the first capillary hemangioma of the tufted variant being reported with a recurrence after 7 years after surgical excision in a 47-year-old male patient.


Assuntos
Meato Acústico Externo/patologia , Neoplasias da Orelha/diagnóstico , Hemangioma Capilar/diagnóstico , Hemangioma/diagnóstico , Recidiva Local de Neoplasia/diagnóstico , Neoplasias Cutâneas/diagnóstico , Diagnóstico Diferencial , Seguimentos , Perda Auditiva Condutiva/diagnóstico , Hemangioma Capilar/patologia , Humanos , Masculino , Pessoa de Meia-Idade
9.
J Craniofac Surg ; 24(6): e539-41, 2013 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-24220460

RESUMO

Facial nerve (FN) macrodehiscence, in contrast to microdehiscence, generally occurs as a result of chronic otitis media and is rarely seen congenitally. A patient with normal hearing who had no history of ear disease or ear operation came to the clinic with recurrent facial paralysis (FP) and frequent blockage of the external ear canal with epithelial debris complaints. In the explorative ear surgery, we observed that the posterior wall of the external ear canal or tympanic ring was absent, a large external ear cavity was covered with a thin skin, the FN was under the skin, and the tympanic-mastoid segment of the FN and chorda tympani extending to the stylomastoid foramen was completely open. FP episodes were associated with the unprotected FN.To prevent an attack of FP, and to self-clean the external ears, mastoid obliteration surgery was performed, and the mastoid segment of the FN was covered with a conchal cartilage graft. This case was diagnosed as congenital aplasia of the external ear canal due to the tympanic bone aplasia-mastoid bone hypoplasia, and the dehiscence of the mastoid-tympanic segment of the FN, and as a cause of recurrent FP, has never to date been identified.


Assuntos
Meato Acústico Externo/anormalidades , Doenças do Nervo Facial/complicações , Paralisia Facial/etiologia , Osso Petroso/anormalidades , Cartilagem/transplante , Nervo da Corda do Tímpano/cirurgia , Meato Acústico Externo/cirurgia , Fáscia/transplante , Feminino , Humanos , Processo Mastoide/anormalidades , Processo Mastoide/cirurgia , Pessoa de Meia-Idade , Otoscopia , Osso Petroso/cirurgia , Recidiva
10.
Kulak Burun Bogaz Ihtis Derg ; 22(3): 136-40, 2012.
Artigo em Turco | MEDLINE | ID: mdl-22663922

RESUMO

OBJECTIVES: In this study, we evaluated the results of endoscopic dacryocystorhinostomy and bicanalicular silicone tube intubation (EDCR + BSTI) surgery in the patients with epiphora due to nasolacrimal duct obstruction. PATIENTS AND METHODS: A total of 120 eyes in 112 patients (40 males, 72 females; mean age 42; range 6 to 74 years) who underwent EDCR + BSTI surgery under general anesthesia between August 2006 and December 2010 were analyzed retrospectively. RESULTS: Of the patients, 104 underwent unilateral surgery, while eight underwent bilateral surgery. One hundred nine of 120 surgeries were primary, whereas 11 were revision surgery. Follow-up was performed on a regular basis in the first week, at one, three, six, and 12 months following surgery. Successful results were obtained in 113 of 120 operation, however seven patients required revision surgery. Repeated EDCR + BSTI surgery gave successful results in all cases, as assessed during the follow-up visits. CONCLUSION: EDCR + BSTI surgery is a primary treatment of choice for the patients with epiphora due to nasolacrimal duct obstruction with a high success rate.


Assuntos
Dacriocistorinostomia , Adolescente , Adulto , Idoso , Criança , Feminino , Seguimentos , Humanos , Intubação/instrumentação , Masculino , Pessoa de Meia-Idade , Reoperação/estatística & dados numéricos , Estudos Retrospectivos , Silicones , Resultado do Tratamento , Adulto Jovem
11.
Braz J Otorhinolaryngol ; 88(1): 105-111, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-34602350

RESUMO

OBJECTIVE: Cisplatin is an antineoplastic agent used in adults and children for the treatment of various malignant diseases. It can cause irreversible ototoxicity. Genistein is a phytoestrogen. Genistein functions as an antioxidant and cell cycle inhibitor by inhibiting the DNA topoisomerase and tyrosine protein kinase enzymes. The protective effect of genistein in preventing cisplatin-induced ototoxicity and levels of the oxidative stress was investigated. METHODS: 32 Sprague Dawley rats were used in 4 groups (control, cisplatin, cisplatin + genistein, genistein). Otoacoustic emission measurements of the distortion product were performed on the 1st, 2nd and 5th days of the test protocol. Serum malondialdehyde, superoxide dismutase, catalase, glutathione peroxidase, total antioxidant status, total oxidant status and oxidative stress index measurements were made. RESULTS: The hearing of the cisplatin + genistein group was found to be better than that of the cisplatin group. While the malondialdehyde, total oxidant status and oxidative stress index parameters decreased significantly in the cisplatin + genistein group compared to the cisplatin group, superoxide dismutase increased significantly (p < 0.05). CONCLUSION: Genistein showed positive effects against ototoxicity with its antioxidant effect. LEVEL OF EVIDENCE: Level 3.


Assuntos
Antineoplásicos , Ototoxicidade , Animais , Antineoplásicos/toxicidade , Antioxidantes/farmacologia , Cisplatino/toxicidade , Cóclea , Genisteína/farmacologia , Estresse Oxidativo , Ratos , Ratos Sprague-Dawley
12.
Braz J Otorhinolaryngol ; 85(6): 716-723, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-30057254

RESUMO

INTRODUCTION: Septal perforation is a condition characterized by loss of cartilage and/or bony structures along with the mucoperichondrium and mucoperiosteum lining them. The etiology includes a history of nasal surgery or trauma, nose picking, bilateral septal cauterization, overuse of nasal sprays, cocaine abuse, vasculitis, and malignancies. OBJECTIVE: Comparison of quality of life in patients with septal perforation after conservative or surgical treatment, and a new approach for the determination of the diameter of the perforation from a different point of view. METHODS: The diameter of septal perforation, total vertical diameter of septum, and horizontal diameter of the perforation were measured in a total of 34 patients. Nineteen of the patients underwent surgical septal perforation repair, and 15 of them received septal button application. The patients were asked to complete the Glasgow Benefit Inventory quality of life questionnaire. RESULTS: The septal perforation successfully healed in 18 of 19 patients who underwent surgical treatment. The quality of life scores were statistically significantly higher in the surgical treatment group when compared to the button group (p<0.05). CONCLUSION: The septal perforation classification we propose would be beneficial for providing realistic dimensions, treatment methods, and surgical techniques.


Assuntos
Perfuração do Septo Nasal/classificação , Septo Nasal/cirurgia , Qualidade de Vida/psicologia , Adulto , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Perfuração do Septo Nasal/diagnóstico por imagem , Perfuração do Septo Nasal/cirurgia , Inquéritos e Questionários , Adulto Jovem
13.
Medeni Med J ; 34(4): 360-367, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-32821462

RESUMO

OBJECTIVE: Cartilage is a rigid material that is highly resistant to infection and retraction and is tolerated well by the middle ear. The purpose of this study was to review retrospectively the results of cases of mastoid cavity obliteration with cartilage performed after canal wall down (CWD) mastoidectomy and to discuss the literature. METHOD: Of 983 patients who underwent surgery for chronic otitis media between January 2000 and June 2012, 54 patients who underwent CWD mastoidectomy plus mastoid cavity obliteration with cartilage and who were followed up regularly were selected from the database and invited for re-evaluation. All patients who came for a follow up after the invitation were examined and their data were evaluated retrospectively. RESULTS: Thirty-five of the patients who accepted the invitation were included in the study. All of the patients in the study underwent mastoid cavity obliteration with conchal and/or tragal cartilage grafts. The duration of follow up ranged from 21 to 41 months (average, 27.3 months). Epithelization occurred in all patients with dry cavity, except one who had residual cholesteatoma and underwent revision surgery. CONCLUSION: The results of this study indicate that cartilage can be preferred for obliteration of mastoid cavity after CWD mastoidectomy.

14.
Braz. j. otorhinolaryngol. (Impr.) ; 88(1): 105-111, Jan.-Feb. 2022. tab, graf
Artigo em Inglês | LILACS-Express | LILACS | ID: biblio-1364573

RESUMO

Abstract Highlights Cisplatin is an antineoplastic agent used malignant diseases. Cisplatin ototoxicity is generally bilateral, irreversible, and progressive. Genistein is a phytoestrogen. Genistein functions as antioxidant and cell cycle inhibitor by inhibiting DNA topoisomerase. Genistein showed positive effects on ototoxicity with its antioxidant. Objective Cisplatin is an antineoplastic agent used in adults and children for the treatment of various malignant diseases. It can cause irreversible ototoxicity. Genistein is a phytoestrogen. Genistein functions as an antioxidant and cell cycle inhibitor by inhibiting the DNA topoisomerase and tyrosine protein kinase enzymes. The protective effect of genistein in preventing cisplatin-induced ototoxicity and levels of the oxidative stress was investigated. Methods 32 Sprague Dawley rats were used in 4 groups (control, cisplatin, cisplatin + genistein, genistein). Otoacoustic emission measurements of the distortion product were performed on the 1st, 2nd and 5th days of the test protocol. Serum malondialdehyde, superoxide dismutase, catalase, glutathione peroxidase, total antioxidant status, total oxidant status and oxidative stress index measurements were made. Results The hearing of the cisplatin + genistein group was found to be better than that of the cisplatin group. While the malondialdehyde, total oxidant status and oxidative stress index parameters decreased significantly in the cisplatin + genistein group compared to the cisplatin group, superoxide dismutase increased significantly (p < 0.05). Conclusion Genistein showed positive effects against ototoxicity with its antioxidant effect. Level of evidence Level 3.


Resumo DESTAQUES A cisplatina é um agente antineoplásico usado em lesões malignas. A ototoxicidade da cisplatina é geralmente bilateral, irreversível e progressiva. A genisteína é um fitoestrógeno. A genisteína funciona como antioxidante e inibidor do ciclo celular ao inibir a topoisomerase do DNA. A genisteína apresentou efeitos positivos sobre a ototoxicidade com seu efeito antioxidante. Objetivo A cisplatina é um agente antineoplásico usado em adultos e crianças para o tratamento de diversas lesões malignas. Pode causar ototoxicidade irreversível. A genisteína é um fitoestrógeno que funciona como antioxidante e inibidor do ciclo celular ao inibir as enzimas DNA topoisomerase e tirosina-quinase. O efeito protetor da genisteína na prevenção da ototoxicidade induzida pela cisplatina e os níveis de estresse oxidativo foram investigados. Método Trinta e dois ratos Sprague Dawley foram usados em 4 grupos (controle, cisplatina, cisplatina + genisteína, genisteína). As medidas das emissões otoacústicas por produto de distorção foram tomadas nos dias 1, 2 e 5 do protocolo do teste. Foram medidos os níveis séricos de malondialdeído, superóxido dismutase, catalase, glutationa peroxidase, estado antioxidante total, estado oxidante total e índice de estresse oxidativo. Resultados A audição do grupo cisplatina + genisteína foi melhor do que a do grupo cisplatina. Enquanto os parâmetros malondialdeído, estado oxidante total e índice de estresse oxidativo diminuíram significantemente no grupo cisplatina + genisteína em comparação com o grupo cisplatina, o superóxido dismutase mostrou aumento significantemente (p < 0,05). Conclusão A genisteína apresentou efeitos positivos contra a ototoxicidade com seu efeito antioxidante. Nível de evidência Nível 3.

15.
Otolaryngol Head Neck Surg ; 134(1): 41-7, 2006 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-16399179

RESUMO

OBJECTIVES: Comprehensive examination of the internal nasal valve (INV) using objective methods. STUDY DESIGN AND SETTING: In this prospective study, 248 nasal cavities were examined by nasal endoscopy, acoustic rhinometry (ARM), and rhinomanometry (RMM). RESULTS: Endoscopic examination allowed to suggest a novel classification of INV: convex, concave, sharp angle, blunt angle, twisted caudal border, and angle occupied by the septal body. The INV angle occupied with septal body type was found to have increased nasal resistances compared with the sharp-angled internal nasal valve type (P < 0.05). Convex, concave, and sharp-angle types of INV angles were found different (P < 0.01). CONCLUSIONS: INV should be examined objectively before any INV surgery. A novel description of the INV configurations and their effects on nasal respiration found in this study may increase our understanding and lead surgical approaches more adequately. A surgical attempt to augment INV angle value may impact positively on nasal resistance. EBM RATING: C-4.


Assuntos
Cavidade Nasal/anatomia & histologia , Septo Nasal/anatomia & histologia , Adolescente , Adulto , Pesos e Medidas Corporais , Endoscopia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Prospectivos , Valores de Referência , Rinomanometria , Rinometria Acústica
16.
Int J Pediatr Otorhinolaryngol ; 70(1): 121-7, 2006 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-16024095

RESUMO

OBJECTIVE: Auricular abnormalities are important for early diagnosis of the birth defects in the prematures and newborns. Auricular antropometric studies in healthy premature and mature population depend on their gestational age are limited and insufficient. The aims of this study were to reveal antropometric growth and dynamics of the auricle in the healthy newborns from the 28th to the 42nd gestation weeks. MATERIALS AND METHODS: A total of 600 newborns were evaluated in 40 groups. Each group comprising 20 preterm or term newborns according to their sexes and gestational weeks. Six surface dimensions were performed directly from the right ears of the subjects: the length from the superaurale to subaurale, the width from the tragus to helix, the width from the tragus to antihelix, the conchal depth, the distance from the helix to mastoid at superaural level and the distance from the helix to mastoid at tragal level. The frequency of the prominent ear deformity and lobule attachment were also noted. RESULTS: The results of auricular antropometric measurements of healthy preterm and term newborns in different gestational weeks were to determined. No statistical differences of auricular length were found between male and female infants. The incidence of the prominent ear deformity and attached lobule was 8.16 and 27.4%, respectively. CONCLUSIONS: Normal anthropometric features for healthy newborns on the basis of gestational age are very important for the diagnosis of a variety of congenital malformations or syndromes. In this study, antropometric measurements of the auricle in the healthy preterm and term newborns on the basis of gestational age in our region were noted. Similar anthropometric studies in the preterm and term newborns at different geographic and various socioeconomic areas should be performed to constitute normative data in the literature.


Assuntos
Orelha Externa/anatomia & histologia , Orelha Externa/crescimento & desenvolvimento , Recém-Nascido/crescimento & desenvolvimento , Recém-Nascido Prematuro/crescimento & desenvolvimento , Antropometria , Feminino , Idade Gestacional , Humanos , Masculino , Valores de Referência
17.
Clin Exp Otorhinolaryngol ; 9(1): 14-20, 2016 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-26976021

RESUMO

OBJECTIVES: This study was aimed to investigate the protective effects of dexpanthenol (Dxp) on against cisplatin-induced ototoxicity. METHODS: To examine this effect, distortion product otoacoustic emissions (DPOAEs) measurements and serum levels of oxidative and antioxidant status (including malondialdehyde, superoxide dismutase, catalase, glutathione, glutathione peroxidase, total oxidant status, total antioxidant status, and oxidative stress index) were evaluated. Thirty-two adult female Wistar albino rats were randomly divided into 4 equal groups; control (K), cisplatin (C), cisplatin plus Dxp (CD), and Dxp (D). In all groups DPOAEs measurements, between 996 and 10,078 Hz as DPOAEs and input/output functions, were performed on days 0, 1th, 5th, and 12th. Prior to death, the last DPOAEs measurements and blood samples were taken. RESULTS: In the C group, statistically significant differences were detected at all frequencies between 0 and 5 days and 0 and 12 days measurements (P<0.05). Serum level of oxidant and antioxidant status were detected statistically significantly changed in this group versus K group (P<0.05). Contrary to the C group, in the CD group hearing ability was seen largely preserved at many frequencies and serum levels of all biochemical parameters were shifted toward normal values, similar to the K group. No significant differences were detected in the either D or K group's measurements. CONCLUSION: According to these results, Dxp may prevent cisplatin-induced ototoxicity.

18.
Braz J Otorhinolaryngol ; 81(3): 307-11, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-25900719

RESUMO

INTRODUCTION: There is an ongoing debate about the existence and effects of Helicobacter pylori (Hp) in adenotonsillar tissue. OBJECTIVE: A clinical study was conducted to assess the existence of Hp in the adenoid and/or adenotonsillar tissues, which were surgically excised due to chronic adenotonsillitis. METHODS: Phosphoglucosamine mutase gene for the detection of Hp and cytotoxin-associated gene as virulence gene were examined in 84 adenotonsillar tissues obtained from 64 patients and patients' serum by using polymerase chain reaction. RESULTS: Hp IgG was detected in 57 (89%) patients' serum. A total of seven tissue samples from 64 patients (10.9%) were found positive for Hp DNA, of which five were adenoids and two were tonsil tissues. All polymerase chain reaction positive samples were also positive for the cytotoxin-associated gene, which is a virulence determinant for the organism. CONCLUSION: This study suggests that children are exposed to Hp at an early age of their life in this province. Hp may have a role in the pathogenesis of chronic adenotonsillitis, especially in endemic areas.


Assuntos
Tonsila Faríngea/microbiologia , Portador Sadio/microbiologia , Helicobacter pylori/isolamento & purificação , Tonsila Palatina/microbiologia , Tonsila Faríngea/patologia , Adolescente , Antígenos de Bactérias , Proteínas de Bactérias , Criança , Pré-Escolar , Feminino , Infecções por Helicobacter/epidemiologia , Humanos , Hipertrofia/microbiologia , Lactente , Masculino , Tonsila Palatina/patologia , Prevalência , Reação em Cadeia da Polimerase em Tempo Real
19.
Int J Pediatr Otorhinolaryngol ; 67(11): 1169-77, 2003 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-14597366

RESUMO

OBJECTIVE: The aim of this study was to reveal the anthropometric growth of auricula from birth to the age of 18 years and to bring out the dynamics of ear growth. MATERIAL AND METHODS: A total of 1552 children in 50 groups were evaluated. Six surface measurements were performed directly on the right auricle of the subjects: the length from the superaurale to subaurale, the width from the tragus to helix, the width from the tragus to antihelix, the conchal depth, the height from the helix to mastoid at superauraler level, and the height from the helix to mastoid at tragal level. The frequency of prominent ear deformity and the degree of attachment of the lobule were also noted. RESULTS: Vertical auricular growth was complete in girls at the age of 11 and in boys at the age of 12, whereas the auricular width from the tragus to helix, the height from the helix to mastoid at superauraler level and the height from the helix to mastoid at tragal level were found almost complete at the age of 6. The auricular width from the tragus to antihelix attained its full size at 6 months for girls and 12 months for boys. The conchal depth was found almost complete at the age of 5 in both sexes. The incidence of prominent ear deformity and attached lobule was 9.8 and 26.5%, respectively. CONCLUSIONS: Different ear growth pattern and maturation size from previously published reports are obtained in different populations. There is still need for future studies comparing populations with different social and ethnic background to interpret common knowledge about the size of the ear. This study gives dimensional information and the growth pattern of the auricle, and therefore may reveal important implications for the adequate timing of the surgical treatment of auricular deformity.


Assuntos
Orelha Externa/crescimento & desenvolvimento , Adolescente , Criança , Pré-Escolar , Orelha Externa/anatomia & histologia , Feminino , Humanos , Lactente , Recém-Nascido , Masculino
20.
Braz. j. otorhinolaryngol. (Impr.) ; 85(6): 716-723, Nov.-Dec. 2019. tab, graf
Artigo em Inglês | LILACS | ID: biblio-1055500

RESUMO

Abstract Introduction: Septal perforation is a condition characterized by loss of cartilage and/or bony structures along with the mucoperichondrium and mucoperiosteum lining them. The etiology includes a history of nasal surgery or trauma, nose picking, bilateral septal cauterization, overuse of nasal sprays, cocaine abuse, vasculitis, and malignancies. Objective: Comparison of quality of life in patients with septal perforation after conservative or surgical treatment, and a new approach for the determination of the diameter of the perforation from a different point of view. Methods: The diameter of septal perforation, total vertical diameter of septum, and horizontal diameter of the perforation were measured in a total of 34 patients. Nineteen of the patients underwent surgical septal perforation repair, and 15 of them received septal button application. The patients were asked to complete the Glasgow Benefit Inventory quality of life questionnaire. Results: The septal perforation successfully healed in 18 of 19 patients who underwent surgical treatment. The quality of life scores were statistically significantly higher in the surgical treatment group when compared to the button group (p < 0.05). Conclusion: The septal perforation classification we propose would be beneficial for providing realistic dimensions, treatment methods, and surgical techniques.


Resumo Introdução: A perfuração septal é uma condição caracterizada pela perda de estruturas cartilaginosas e/ou ósseas, juntamente com o mucopericôndrio e o mucoperiósteo que as revestem. A etiologia inclui um histórico de cirurgia nasal ou trauma, cutucar o nariz, cauterização septal bilateral, uso excessivo de sprays nasais, abuso de cocaína, vasculite e neoplasias malignas. Objetivo: Comparar a qualidade de vida em pacientes com perfuração septal após tratamento conservador ou cirúrgico e uma nova abordagem para a determinação do diâmetro da perfuração sob um diferente ponto de vista. Método: O diâmetro da perfuração septal, o diâmetro vertical total do septo e o diâmetro horizontal da perfuração foram medidos em 34 pacientes; 19 foram submetidos ao reparo cirúrgico da perfuração septal e 15 receberam a aplicação do botão septal. Os pacientes foram solicitados a preencher o questionário de qualidade de vida Glasgow Benefit Inventory. Resultados: A perfuração septal cicatrizou com sucesso em 18 de 19 pacientes submetidos a tratamento cirúrgico. Os escores de qualidade de vida foram estatisticamente significativamente maiores no grupo de tratamento cirúrgico quando comparados aos do grupo que recebeu o botão septal (p < 0,05). Conclusão: A classificação de perfuração septal que fizemos seria benéfica para fornecer dimensões, métodos de tratamento e técnicas cirúrgicas realistas.


Assuntos
Humanos , Masculino , Feminino , Adulto , Pessoa de Meia-Idade , Adulto Jovem , Qualidade de Vida/psicologia , Perfuração do Septo Nasal/classificação , Septo Nasal/cirurgia , Inquéritos e Questionários , Perfuração do Septo Nasal/cirurgia , Perfuração do Septo Nasal/diagnóstico por imagem
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