Detalhe da pesquisa
1.
Structural insights into the DNA recognition mechanism by the bacterial transcription factor PdxR.
Nucleic Acids Res
; 51(15): 8237-8254, 2023 08 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37378428
2.
A gene-nutrient interaction between vitamin B6 and serine hydroxymethyltransferase (SHMT) affects genome integrity in Drosophila.
J Cell Physiol
; 238(7): 1558-1566, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37183313
3.
4'-Deoxypyridoxine disrupts vitamin B6 homeostasis in Escherichia coli K12 through combined inhibition of cumulative B6 uptake and PLP-dependent enzyme activity.
Microbiology (Reading)
; 169(4)2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37040165
4.
Identification and characterization of the pyridoxal 5'-phosphate allosteric site in Escherichia coli pyridoxine 5'-phosphate oxidase.
J Biol Chem
; 296: 100795, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34019876
5.
Vitamin B6 rescues insulin resistance and glucose-induced DNA damage caused by reduced activity of Drosophila PI3K.
J Cell Physiol
; 237(9): 3578-3586, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35678366
6.
Thiamine-dependent regulation of mammalian brain pyridoxal kinase in vitro and in vivo.
J Neurochem
; 161(1): 20-39, 2022 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-35050500
7.
The moonlighting RNA-binding activity of cytosolic serine hydroxymethyltransferase contributes to control compartmentalization of serine metabolism.
Nucleic Acids Res
; 47(8): 4240-4254, 2019 05 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30809670
8.
Functional Inactivation of Drosophila GCK Orthologs Causes Genomic Instability and Oxidative Stress in a Fly Model of MODY-2.
Int J Mol Sci
; 22(2)2021 Jan 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-33477627
9.
Characterization of Novel Pathogenic Variants Causing Pyridox(am)ine 5'-Phosphate Oxidase-Dependent Epilepsy.
Int J Mol Sci
; 22(21)2021 Nov 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34769443
10.
PHA-680626 Is an Effective Inhibitor of the Interaction between Aurora-A and N-Myc.
Int J Mol Sci
; 22(23)2021 Dec 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34884931
11.
Allosteric feedback inhibition of pyridoxine 5'-phosphate oxidase from Escherichia coli.
J Biol Chem
; 294(43): 15593-15603, 2019 10 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-31484724
12.
Human Cytosolic and Mitochondrial Serine Hydroxymethyltransferase Isoforms in Comparison: Full Kinetic Characterization and Substrate Inhibition Properties.
Biochemistry
; 57(51): 6984-6996, 2018 12 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-30500180
13.
Differential inhibitory effect of a pyrazolopyran compound on human serine hydroxymethyltransferase-amino acid complexes.
Arch Biochem Biophys
; 653: 71-79, 2018 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29991441
14.
Differential 3-bromopyruvate inhibition of cytosolic and mitochondrial human serine hydroxymethyltransferase isoforms, key enzymes in cancer metabolic reprogramming.
Biochim Biophys Acta
; 1864(11): 1506-17, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27530298
15.
Pyridoxine-5'-phosphate oxidase (Pnpo) deficiency: Clinical and biochemical alterations associated with the C.347g>A (P.·Arg116gln) mutation.
Mol Genet Metab
; 122(1-2): 135-142, 2017 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28818555
16.
Study of DNA binding and bending by Bacillus subtilis GabR, a PLP-dependent transcription factor.
Biochim Biophys Acta Gen Subj
; 1861(1 Pt A): 3474-3489, 2017 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-27640111
17.
Glucose 6-phosphate and alcohol dehydrogenase activities are components of dynamic macromolecular depots structures.
Biochim Biophys Acta
; 1850(6): 1120-30, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25662817
18.
On the mechanism of Escherichia coli pyridoxal kinase inhibition by pyridoxal and pyridoxal 5'-phosphate.
Biochim Biophys Acta
; 1854(9): 1160-6, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-25655354
19.
Characterization of the transcription factor encoding gene, KlADR1: metabolic role in Kluyveromyces lactis and expression in Saccharomyces cerevisiae.
Microbiology (Reading)
; 162(11): 1933-1944, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27655407
20.
Vitamin B6 deficiency cooperates with oncogenic Ras to induce malignant tumors in Drosophila.
Cell Death Dis
; 15(6): 388, 2024 Jun 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38830901