Detalhe da pesquisa
1.
AI-guided pipeline for protein-protein interaction drug discovery identifies a SARS-CoV-2 inhibitor.
Mol Syst Biol
; 20(4): 428-457, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38467836
2.
The pathobiology of perturbed mutant huntingtin protein-protein interactions in Huntington's disease.
J Neurochem
; 151(4): 507-519, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31418858
3.
LuTHy: a double-readout bioluminescence-based two-hybrid technology for quantitative mapping of protein-protein interactions in mammalian cells.
Mol Syst Biol
; 14(7): e8071, 2018 07 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-29997244
4.
Integrated transcriptome and proteome analysis reveals posttranscriptional regulation of ribosomal genes in human brain organoids.
Elife
; 122023 03 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-36989136
5.
AI-guided pipeline for protein-protein interaction drug discovery identifies a SARS-CoV-2 inhibitor.
bioRxiv
; 2023 Jun 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-37398436
6.
CellFIE: CRISPR- and Cell Fusion-based Two-hybrid Interaction Mapping of Endogenous Proteins.
J Mol Biol
; 433(24): 167305, 2021 12 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34655654
7.
Maximizing binary interactome mapping with a minimal number of assays.
Nat Commun
; 10(1): 3907, 2019 08 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-31467278
8.
Current Approaches Toward Quantitative Mapping of the Interactome.
Front Genet
; 7: 74, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27200083
9.
DULIP: A Dual Luminescence-Based Co-Immunoprecipitation Assay for Interactome Mapping in Mammalian Cells.
J Mol Biol
; 427(21): 3375-88, 2015 Oct 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-26264872
10.
Spontaneous self-assembly of pathogenic huntingtin exon 1 protein into amyloid structures.
Essays Biochem
; 56: 167-80, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25131594
11.
Polyglutamine-rich suppressors of huntingtin toxicity act upstream of Hsp70 and Sti1 in spatial quality control of amyloid-like proteins.
PLoS One
; 9(5): e95914, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24828240
12.
The Hsp70/90 cochaperone, Sti1, suppresses proteotoxicity by regulating spatial quality control of amyloid-like proteins.
Mol Biol Cell
; 24(23): 3588-602, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24109600