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1.
J Acoust Soc Am ; 131(5): 3627-37, 2012 May.
Artigo em Inglês | MEDLINE | ID: mdl-22559340

RESUMO

An implementation of a quarter-wavelength standing wave separator that exploits an air drum to achieve the pressure node is presented and characterized experimentally. The air drum configuration was implemented and tested in a set-up with a 40 kHz transducer immersed in a water tank with the quarter-wavelength gap being approximately 9 mm wide. Injection of suspensions of 5 µm and 45 µm diameter polystyrene particles at flow rates of 30 ml/h and 60 ml/h was studied and particle deflection towards the pressure node at the air drum surface was observed for a range of acoustic pressures. Computational results on single particle trajectories show good agreement with the experimental findings for the 45 µm particles, but not for the 5 µm particles. These were considered to behave as aggregates of higher effective dimension, due to their much higher number density relative to the 45 µm particles in the suspensions used. The set-up developed in this study includes a robust method for achieving a pressure node in a quarter-wavelength system and can represent the first step toward the development of an alternative separator configuration in respect to small channel MHz range operated systems for the manipulation of particles streams.

2.
IEEE Trans Biomed Eng ; 58(2): 282-90, 2011 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-20679023

RESUMO

A computational fluid dynamics (CFD) model is presented to simulate the removal of lipid particles from blood using a novel ultrasonic quarter-wavelength separator. The Lagrangian-Eulerian CFD model accounts for conservation of mass and momentum, for the presence of lipid particles of a range of diameters, for the acoustic force as experienced by the particles in the blood, as well as for gravity and other particle-fluid interaction forces. In the separator, the liquid flows radially inward within a fluid chamber formed between a disc-shaped transducer and a disc-shaped reflector. Following separation of the lipid particles, blood exits the separator axially through a central opening on the disc-shaped reflector. Separator diameters studied varied between 12 and 18 cm, and gap sizes between the discs of 600 µm, 800 µm and 1 mm were considered. Results show a strong effect of residence time of the particles within the chamber on the separation performance. Different separator configurations were identified, which could give a lipid removal performance of 95% or higher when processing 62.5 cm (3)/min of blood. The developed model provides a design method for the selection of geometric and operating parameters for the ultrasonic separator.


Assuntos
Remoção de Componentes Sanguíneos/métodos , Hemorreologia/fisiologia , Lipídeos/sangue , Modelos Cardiovasculares , Ultrassom/métodos , Transfusão de Sangue Autóloga , Procedimentos Cirúrgicos Cardíacos , Simulação por Computador , Humanos , Lipídeos/isolamento & purificação , Pericárdio , Transdutores
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