Detalhe da pesquisa
1.
Pharmacological and mechanistic study of PS1, a Pdia4 inhibitor, in ß-cell pathogenesis and diabetes in db/db mice.
Cell Mol Life Sci
; 80(4): 101, 2023 Mar 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-36935456
2.
Synthesis and biological evaluation of C-4 substituted phenoxazine-bearing hydroxamic acids with potent class II histone deacetylase inhibitory activities.
J Enzyme Inhib Med Chem
; 38(1): 2212326, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37190931
3.
Identification of a dual FLT3 and MNK2 inhibitor for acute myeloid leukemia treatment using a structure-based virtual screening approach.
Bioorg Chem
; 121: 105675, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35182882
4.
Synthesis of Yakuchinone B-Inspired Inhibitors against Islet Amyloid Polypeptide Aggregation.
J Nat Prod
; 84(4): 1096-1103, 2021 04 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-33600175
5.
Investigation of Selected Flavonoid Derivatives as Potent FLT3 Inhibitors for the Potential Treatment of Acute Myeloid Leukemia.
J Nat Prod
; 84(1): 1-10, 2021 01 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-33393294
6.
Biological Evaluation of Selected Flavonoids as Inhibitors of MNKs Targeting Acute Myeloid Leukemia.
J Nat Prod
; 83(10): 2967-2975, 2020 10 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-33026809
7.
Total Synthesis and Metabolic Stability of Hispidulin and Its d-Labelled Derivative.
Molecules
; 22(11)2017 Nov 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29113055
8.
Design, synthesis, and biological activity of dual monoamine oxidase A and heat shock protein 90 inhibitors, N-Methylpropargylamine-conjugated 4-isopropylresorcinol for glioblastoma.
Eur J Med Chem
; 256: 115459, 2023 Aug 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37172473
9.
Design, synthesis, and biological evaluation of indolin-2-one derivatives as novel cyclin-dependent protein kinase 8 (CDK8) inhibitors.
Biomed Pharmacother
; 159: 114258, 2023 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-36708700
10.
O-methylated flavonol as a multi-kinase inhibitor of leukemogenic kinases exhibits a potential treatment for acute myeloid leukemia.
Phytomedicine
; 100: 154061, 2022 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-35364561
11.
Synthesis and biological evaluation of phenothiazine derivative-containing hydroxamic acids as potent class II histone deacetylase inhibitors.
Eur J Med Chem
; 219: 113419, 2021 Jul 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33845233
12.
Synthesis and biological evaluation of acridine-based histone deacetylase inhibitors as multitarget agents against Alzheimer's disease.
Eur J Med Chem
; 192: 112193, 2020 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32151835
13.
Design of Diarylheptanoid Derivatives as Dual Inhibitors Against Class IIa Histone Deacetylase and ß-amyloid Aggregation.
Front Pharmacol
; 9: 708, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30018556
14.
Novel Class IIa-Selective Histone Deacetylase Inhibitors Discovered Using an in Silico Virtual Screening Approach.
Sci Rep
; 7(1): 3228, 2017 06 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-28607401