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1.
J Long Term Eff Med Implants ; 33(2): 79-88, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-36734930

RESUMO

Cancer is established as a major contributor to global burden as millions of deaths are reported every year. Advances in molecular, epidemiologic and clinical research have led to significant improvements in prevention, screening and treatment of tumors. The purpose of the study is to describe the progress of oncology clinical trials performed in Greece during the past decade and the obstacles that still need to be addressed in cancer research. A search was conducted in the public database EU Clinical Trials Register using the algorithm 'cancer AND Greece'. Results included relevant trials approved between 2010 and 2020. A total of 480 trials were approved for conduct in Greece from 2010 to 2020. The majority are multinational, phase III trials, exploring the efficacy and safety of agents in the management of lung cancer and multiple myeloma. A variety of small-molecules and monoclonal antibodies has and is being tested against key binding targets. Based on their promising effects on patients' responses and outcomes, many have been marketed for the treatment of several cancer types and are considered milestones in cancer discovery. It goes without saying that oncology research has made tremendous steps towards the development of potent and tolerable anticancer agents, with Greece having an active role. Current efforts focus on the use of alternative designs and tools aiming at further improving patients' survival and quality of life, while globalization of clinical research is also a matter of high importance.


Assuntos
Antineoplásicos , Neoplasias , Humanos , Antineoplásicos/uso terapêutico , Grécia , Neoplasias/tratamento farmacológico , Neoplasias/metabolismo , Qualidade de Vida , Ensaios Clínicos Fase III como Assunto
2.
Acta Med Acad ; 48(3): 307-311, 2019 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-32124630

RESUMO

OBJECTIVE: The aim of our paper is to present a rare variation of the suprascapular vein, its incidence and clinical significance. CASE REPORT: A rare case of a double suprascapular vein was observed in a digitalized human cadaver on Anatomage Table 5.0. The vein divided into two branches, one passing over the transverse scapular ligament, while the other one coursed underneath the ligament, inside the notch. CONCLUSION: This variation has major clinical importance as it is associated with the appearance of Suprascapular nerve entrapment syndrome.


Assuntos
Ligamentos/anormalidades , Veias/anormalidades , Adulto , Feminino , Humanos , Imageamento Tridimensional , Ligamentos/anatomia & histologia , Escápula/anatomia & histologia , Escápula/irrigação sanguínea , Ombro/anatomia & histologia , Ombro/irrigação sanguínea , Veias/anatomia & histologia
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