Detalhe da pesquisa
1.
Comparison of antibody molecules produced from two cell lines with contrasting productivities and aggregate contents.
Biol Pharm Bull
; 38(2): 306-16, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25501618
2.
Approaches to Quality Risk Management When Using Single-Use Systems in the Manufacture of Biologics.
AAPS PharmSciTech
; 16(5): 993-1001, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26288941
3.
Efficient production of recombinant proteins in suspension CHO cells culture using the Tol2 transposon system coupled with cycloheximide resistance selection.
Sci Rep
; 13(1): 7628, 2023 05 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37165015
4.
Improved Production of Induced Pluripotent Stem Cells Using Dot Pattern Culture Plates.
Tissue Eng Part C Methods
; 29(9): 410-423, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37427413
5.
A clinical-grade HLA haplobank of human induced pluripotent stem cells matching approximately 40% of the Japanese population.
Med
; 4(1): 51-66.e10, 2023 01 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-36395757
6.
Fully human monoclonal antibody directed to proteolytic cleavage site in severe acute respiratory syndrome (SARS) coronavirus S protein neutralizes the virus in a rhesus macaque SARS model.
J Infect Dis
; 203(11): 1574-81, 2011 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21592986
7.
Laminin-511 Activates the Human Induced Pluripotent Stem Cell Survival via α6ß1 Integrin-Fyn-RhoA-ROCK Signaling.
Stem Cells Dev
; 31(21-22): 706-719, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35726387
8.
Semi-3D cultures using Laminin 221 as a coating material for human induced pluripotent stem cells.
Regen Biomater
; 9: rbac060, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36176714
9.
Adhesion Characteristics of Human Pancreatic Islets, Duct Epithelial Cells, and Acinar Cells to a Polymer Scaffold.
Cell Transplant
; 31: 9636897221120500, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36062469
10.
Induced hepatic stem cells are suitable for human hepatocyte production.
iScience
; 25(10): 105052, 2022 Oct 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-36147945
11.
Protocol for the generation of human induced hepatic stem cells using Sendai virus vectors.
STAR Protoc
; 3(4): 101884, 2022 12 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36595898
12.
A chemically-defined plastic scaffold for the xeno-free production of human pluripotent stem cells.
Sci Rep
; 12(1): 2516, 2022 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35169157
13.
Generation of hypoimmunogenic induced pluripotent stem cells by CRISPR-Cas9 system and detailed evaluation for clinical application.
Mol Ther Methods Clin Dev
; 26: 15-25, 2022 Sep 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35755947
14.
A rapid method for simultaneous evaluation of free light chain content and aggregate content in culture media of Chinese hamster ovary cells expressing monoclonal antibodies for cell line screening.
J Biosci Bioeng
; 121(4): 464-70, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26467692
15.
Titer of trastuzumab produced by a Chinese hamster ovary cell line is associated with tricarboxylic acid cycle activity rather than lactate metabolism.
J Biosci Bioeng
; 119(4): 478-85, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25449760
16.
Efficient folding/assembly in Chinese hamster ovary cells is critical for high quality (low aggregate content) of secreted trastuzumab as well as for high production: stepwise multivariate regression analyses.
J Biosci Bioeng
; 118(2): 223-30, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24635945
17.
Regulation of DNA fragmentation: the role of caspases and phosphorylation.
FEBS J
; 278(3): 427-41, 2011 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-21182594
18.
Okadaic acid induces DNA fragmentation via caspase-3-dependent and caspase-3-independent pathways in Chinese hamster ovary (CHO)-K1 cells.
FEBS J
; 277(2): 404-12, 2010 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-19968860
19.
pH Condition in temperature shift cultivation enhances cell longevity and specific hMab productivity in CHO culture.
Cytotechnology
; 52(3): 199-207, 2006 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-19002878