RESUMO
INTRODUCTION: To evaluate patient satisfaction with samfilcon A contact lenses (CLs) in intensive digital device users with myopia and to compare patient satisfaction with samfilcon A lenses to prior experience with senofilcon A or lotrafilcon B CLs. METHODS: This was a comparative, prospective, national study conducted at 14 centers in Turkey. Subjects were adults aged 18 and 45 years with myopia (range -0.25 D to -6.00 D) who spend a minimum of 3 hours viewing digital devices (e.g., computer, smartphone). A subgroup of patients were habitual lens wearers (senofilcon A or lotrafilcon B lens wear for at least 6 months prior to enrollment). The primary assessment was patient satisfaction with samfilcon A lenses (0-100 Likert scale). Secondary assessments included patient satisfaction with samfilcon A lenses compared to patients' habitual lenses, investigator satisfaction with samfilcon A lenses and investigator-evaluated slit lamp examination findings. RESULTS: Samfilcon A lenses were given high overall ratings from both patients and investigators, with a low incidence of ocular symptoms. Overall, patients were highly satisfied with samfilcon A lenses for comfort, vision and overall performance, and stated that they would consider wearing these lenses in the future. Among habitual senofilcon A or lotrafilcon B lens wearers, samfilcon A lenses were rated significantly better than the habitual lenses in regard to comfort, vision and overall performance. Investigator assessments were also highly favorable, both at initial fit and after 4 weeks of follow-up, with no significant findings noted on slit lamp examination. CONCLUSION: Samfilcon A lenses were rated highly by investigators in regard to fit, handling and slit lamp findings, and by novice and habitual lens wearers in regard to comfort, vision and overall performance. These results support the use of samfilcon A lenses among digital device users who seek day-long comfort and good visual acuity.
RESUMO
OBJECTIVES: To determine interindividual variability in the angle between the anatomic axis connecting the fovea and optic disc center and the horizontal meridian using spectral domain optical coherence tomography (OCT). MATERIALS AND METHODS: A total of 260 eyes of 133 subjects (81 women, 52 men) with glaucoma or suspected glaucoma were included in the study retrospectively. Fovea-disc angle (FoDi angle) measurements, determined as the angle between the horizontal meridian passing through the Bruch's membrane opening (BMO) center and the line connecting the fovea and BMO center, were recorded from spectral domain-OCT scans performed by the same investigator. FoDi angle was defined as negative if the fovea was located below the horizontal meridian through the BMO center and positive if the fovea was located above it. RESULTS: The mean age of the participants was 56.5±14.6 years (27-83 years). The mean FoDi angle was -6.43±4.96° (range: -24.40° to +11.60°). Absolute deviation of the fovea BMO axis from the horizontal axis was 0-5° in 83 eyes (31.92%), 5-10° in 124 eyes (47.69%), 10-15° in 41 eyes (15.76%), 15-20° in 10 eyes (3.84%), and greater than 20° in 2 eyes (0.79%). CONCLUSION: Most OCT devices currently used in the treatment and follow-up of glaucoma patients provide peripapillary retinal nerve fiber layer (RNFL) thickness measurements that are made based on a clinical axis in reference to the horizontal meridian passing through the optic disc center. The results of our study reveal interindividual variation in FoDi angle as well as intraindividual differences in FoDi angle between fellow eyes in the same individual. Disparity between clinical and anatomic quadrants could impact RNFL thickness measurements, which may lead to errors in the diagnosis of glaucoma.