Detalhe da pesquisa
1.
An expanded universe of cancer targets.
Cell
; 184(5): 1142-1155, 2021 03 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33667368
2.
Mass Spectrometry-Based Proteogenomics: New Therapeutic Opportunities for Precision Medicine.
Annu Rev Pharmacol Toxicol
; 64: 455-479, 2024 Jan 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-37738504
3.
Metabolic reprogramming ensures cancer cell survival despite oncogenic signaling blockade.
Genes Dev
; 31(20): 2067-2084, 2017 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29138276
4.
DNA methylation epitypes highlight underlying developmental and disease pathways in acute myeloid leukemia.
Genome Res
; 31(5): 747-761, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33707228
5.
Identification and prioritization of myeloid malignancy germline variants in a large cohort of adult patients with AML.
Blood
; 139(8): 1208-1221, 2022 02 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-34482403
6.
MS4A3 promotes differentiation in chronic myeloid leukemia by enhancing common ß-chain cytokine receptor endocytosis.
Blood
; 139(5): 761-778, 2022 02 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34780648
7.
Functional genomic landscape of acute myeloid leukaemia.
Nature
; 562(7728): 526-531, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30333627
8.
Concomitant use of a dual Src/ABL kinase inhibitor eliminates the in vitro efficacy of blinatumomab against Ph+ ALL.
Blood
; 137(7): 939-944, 2021 02 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-32898857
9.
Reversible suppression of T cell function in the bone marrow microenvironment of acute myeloid leukemia.
Proc Natl Acad Sci U S A
; 117(25): 14331-14341, 2020 06 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-32513686
10.
Discovery and characterization of targetable NTRK point mutations in hematologic neoplasms.
Blood
; 135(24): 2159-2170, 2020 06 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32315394
11.
Genome-wide CRISPR screen identifies regulators of MAPK and MTOR pathways mediating sorafenib resistance in acute myeloid leukemia.
Haematologica
; 107(1): 77-85, 2022 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33375770
12.
CSF1R inhibitors exhibit antitumor activity in acute myeloid leukemia by blocking paracrine signals from support cells.
Blood
; 133(6): 588-599, 2019 02 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30425048
13.
Genomic landscape of neutrophilic leukemias of ambiguous diagnosis.
Blood
; 134(11): 867-879, 2019 09 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31366621
14.
BCL6 promotes glioma and serves as a therapeutic target.
Proc Natl Acad Sci U S A
; 114(15): 3981-3986, 2017 04 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28356518
15.
Molecularly targeted drug combinations demonstrate selective effectiveness for myeloid- and lymphoid-derived hematologic malignancies.
Proc Natl Acad Sci U S A
; 114(36): E7554-E7563, 2017 09 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28784769
16.
Gain-of-function mutations in granulocyte colony-stimulating factor receptor (CSF3R) reveal distinct mechanisms of CSF3R activation.
J Biol Chem
; 293(19): 7387-7396, 2018 05 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-29572350
17.
Genomics of chronic neutrophilic leukemia.
Blood
; 129(6): 715-722, 2017 02 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28028025
18.
Ex vivo drug response profiling detects recurrent sensitivity patterns in drug-resistant acute lymphoblastic leukemia.
Blood
; 129(11): e26-e37, 2017 03 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-28122742
19.
Proteolysis targeting chimeric molecules as therapy for multiple myeloma: efficacy, biomarker and drug combinations.
Haematologica
; 104(6): 1209-1220, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30606790
20.
CDK12/13 dual inhibitors are potential therapeutics for acute myeloid leukemia.
Br J Haematol
; 202(1): 195-198, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37182843