Detalhe da pesquisa
1.
Peptide hormone relaxin: from bench to bedside.
Am J Physiol Regul Integr Comp Physiol
; 314(6): R753-R760, 2018 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29412692
2.
Relaxin deficiency results in increased expression of angiogenesis- and remodelling-related genes in the uterus of early pregnant mice but does not affect endometrial angiogenesis prior to implantation.
Reprod Biol Endocrinol
; 14: 11, 2016 Mar 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-27005936
3.
Recombinant human relaxin versus placebo for cervical ripening: a double-blind randomised trial in pregnant women scheduled for induction of labour.
BMC Pregnancy Childbirth
; 16: 260, 2016 09 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-27596360
4.
Serelaxin in acute heart failure patients with preserved left ventricular ejection fraction: results from the RELAX-AHF trial.
Eur Heart J
; 35(16): 1041-50, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24316514
5.
Serelaxin, recombinant human relaxin-2, for treatment of acute heart failure (RELAX-AHF): a randomised, placebo-controlled trial.
Lancet
; 381(9860): 29-39, 2013 Jan 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-23141816
6.
Liver function, in-hospital, and post-discharge clinical outcome in patients with acute heart failure-results from the relaxin for the treatment of patients with acute heart failure study.
J Card Fail
; 20(6): 407-13, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24642379
7.
Effects of serelaxin in subgroups of patients with acute heart failure: results from RELAX-AHF.
Eur Heart J
; 34(40): 3128-36, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23999454
8.
Design of the RELAXin in acute heart failure study.
Am Heart J
; 163(2): 149-55.e1, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-22305830
9.
Relaxin for the treatment of patients with acute heart failure (Pre-RELAX-AHF): a multicentre, randomised, placebo-controlled, parallel-group, dose-finding phase IIb study.
Lancet
; 373(9673): 1429-39, 2009 Apr 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-19329178
10.
Low lymphocyte ratio as a novel prognostic factor in acute heart failure: results from the Pre-RELAX-AHF study.
Cardiology
; 117(3): 190-6, 2010.
Artigo
em Inglês
| MEDLINE | ID: mdl-21088400
11.
Relaxin: review of biology and potential role in treating heart failure.
Curr Heart Fail Rep
; 7(2): 75-82, 2010 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-20424993
12.
Intravenous recombinant human relaxin in compensated heart failure: a safety, tolerability, and pharmacodynamic trial.
J Card Fail
; 15(3): 182-90, 2009 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-19327619
13.
Relaxin, a pleiotropic vasodilator for the treatment of heart failure.
Heart Fail Rev
; 14(4): 321-9, 2009 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-19101795
14.
Relaxin family peptide receptors--from orphans to therapeutic targets.
Drug Discov Today
; 13(15-16): 640-51, 2008 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-18675759
15.
Serelaxin in clinical development: past, present and future.
Br J Pharmacol
; 174(10): 921-932, 2017 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28009437
16.
Relaxin modulates fibroblast function, collagen production, and matrix metalloproteinase-2 expression by cardiac fibroblasts.
Ann N Y Acad Sci
; 1041: 190-3, 2005 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-15956706
17.
Relaxin modulates cardiac fibroblast proliferation, differentiation, and collagen production and reverses cardiac fibrosis in vivo.
Endocrinology
; 145(9): 4125-33, 2004 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-15155573
18.
Effect of serelaxin on mode of death in acute heart failure: results from the RELAX-AHF study.
J Am Coll Cardiol
; 64(15): 1591-8, 2014 Oct 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-25301463
19.
Effect of serelaxin on cardiac, renal, and hepatic biomarkers in the Relaxin in Acute Heart Failure (RELAX-AHF) development program: correlation with outcomes.
J Am Coll Cardiol
; 61(2): 196-206, 2013 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23273292
20.
Early drop in systolic blood pressure and worsening renal function in acute heart failure: renal results of Pre-RELAX-AHF.
Eur J Heart Fail
; 13(9): 961-7, 2011 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-21622980