Detalhe da pesquisa
1.
Structure of the Nanobody-Stabilized Active State of the Kappa Opioid Receptor.
Cell
; 172(1-2): 55-67.e15, 2018 01 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-29307491
2.
An anchor-tether 'hindered' HCN1 inhibitor is antihyperalgesic in a rat spared nerve injury neuropathic pain model.
Br J Anaesth
; 131(4): 745-763, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37567808
3.
Synthesis and Characterization of Azido Aryl Analogs of IBNtxA for Radio-Photoaffinity Labeling Opioid Receptors in Cell Lines and in Mouse Brain.
Cell Mol Neurobiol
; 41(5): 977-993, 2021 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-32424771
4.
Kratom Alkaloids, Natural and Semi-Synthetic, Show Less Physical Dependence and Ameliorate Opioid Withdrawal.
Cell Mol Neurobiol
; 41(5): 1131-1143, 2021 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-33433723
5.
The antinociceptive effects of a dual kappa-delta opioid receptor agonist in the mouse formalin test.
Behav Pharmacol
; 31(2&3): 174-178, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32168026
6.
Multifunctionalization of cetuximab with bioorthogonal chemistries and parallel EGFR profiling of cell-lines using imaging, FACS and immunoprecipitation approaches.
Biochim Biophys Acta
; 1844(12): 2182-92, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25091197
7.
Conditional control of alternative splicing through light-triggered splice-switching oligonucleotides.
J Am Chem Soc
; 137(10): 3656-62, 2015 Mar 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-25734836
8.
Site-specific promoter caging enables optochemical gene activation in cells and animals.
J Am Chem Soc
; 136(19): 7152-8, 2014 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-24802207
9.
Genetically encoded optochemical probes for simultaneous fluorescence reporting and light activation of protein function with two-photon excitation.
J Am Chem Soc
; 136(44): 15551-8, 2014 Nov 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-25341086
10.
Genetic encoding of caged cysteine and caged homocysteine in bacterial and mammalian cells.
Chembiochem
; 15(12): 1793-9, 2014 Aug 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-24976145
11.
Identification of a Novel Neuropeptide S Receptor Antagonist Scaffold Based on the SHA-68 Core.
Pharmaceuticals (Basel)
; 14(10)2021 Oct 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34681248
12.
The mixed kappa and delta opioid receptor agonist, MP1104, attenuates chemotherapy-induced neuropathic pain.
Neuropharmacology
; 185: 108445, 2021 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33383089
13.
Kratom Alkaloids as Probes for Opioid Receptor Function: Pharmacological Characterization of Minor Indole and Oxindole Alkaloids from Kratom.
ACS Chem Neurosci
; 12(14): 2661-2678, 2021 07 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-34213886
14.
Oxidative Metabolism as a Modulator of Kratom's Biological Actions.
J Med Chem
; 64(22): 16553-16572, 2021 11 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-34783240
15.
Controlling opioid receptor functional selectivity by targeting distinct subpockets of the orthosteric site.
Elife
; 102021 02 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33555255
16.
Expanding the genetic code of yeast for incorporation of diverse unnatural amino acids via a pyrrolysyl-tRNA synthetase/tRNA pair.
J Am Chem Soc
; 132(42): 14819-24, 2010 Oct 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-20925334
17.
G protein-biased kratom-alkaloids and synthetic carfentanil-amide opioids as potential treatments for alcohol use disorder.
Br J Pharmacol
; 177(7): 1497-1513, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31705528
18.
Synthesis and Pharmacology of a Novel µ-δ Opioid Receptor Heteromer-Selective Agonist Based on the Carfentanyl Template.
J Med Chem
; 63(22): 13618-13637, 2020 11 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-33170687
19.
MP1104, a mixed kappa-delta opioid receptor agonist has anti-cocaine properties with reduced side-effects in rats.
Neuropharmacology
; 150: 217-228, 2019 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30768946
20.
Synthesis of spiro-2,6-dioxopiperazine and spiro-2,6-dioxopyrazine scaffolds using amino acids in a three-component reaction to generate potential Sigma-1 (σ1) receptor selective ligands.
Eur J Med Chem
; 164: 241-251, 2019 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30597325