Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 21
Filtrar
Mais filtros

Base de dados
Tipo de documento
Intervalo de ano de publicação
1.
Nanotechnology ; 31(24): 244003, 2020 Mar 27.
Artigo em Inglês | MEDLINE | ID: mdl-32066120

RESUMO

The influence of hydrogen plasma treatment on the electrical and optical properties of vertical GaN nanowire (NW)/Si heterostructures synthesized via plasma assisted molecular beam epitaxy is studied. The effect of the treatment is thoroughly studied via variation of the passivation duration. Photoluminescence investigation demonstrates that the passivation affects the doping of the GaN NWs. The samples were processed as photodiodes with a top transparent electrode to obtain detailed information about the n-GaN NWs/p-Si heterointerface under illumination. The electron beam induced current measurements demonstrated the absence of potential barriers between the active parts of the diode and the contacts, indicating ohmic behavior of the latter. I-V characteristics obtained in the dark and under illumination show that hydrogen can effectively passivate the recombination centers at the GaN NWs/Si heterointerface. The optimum passivation duration, providing improved electrical properties, is found to be 10 min within the studied passivation regimes. It is demonstrated that longer treatment causes degradation of the electrical properties. The discovered phenomenon is discussed in detail.

2.
Nanotechnology ; 30(39): 395602, 2019 Sep 27.
Artigo em Inglês | MEDLINE | ID: mdl-31234150

RESUMO

The role of Si (111) substrate surface preparation and buffer layer composition in the growth, electronic and optical properties of the GaN nanowires (NWs) synthesized via plasma-assisted molecular beam epitaxy is studied. A comparison study of GaN NWs growth on the bare Si (111) substrate, silicon nitride interlayer, predeposited AlN and GaO x buffer layers, monolayer thick Ga wetting layer and GaN seeding layer prepared by the droplet epitaxy is performed. It is demonstrated that the homogeneity and the morphology of the NW arrays drastically depend on the chosen buffer layer and surface preparation technique. An effect of the buffer and seeding layers on the nucleation and desorption is also discussed. The lowest NWs surface density of 14 µm-2 is obtained on AlN buffer layer and the highest density exceeding the latter value by more than an order of magnitude corresponds to the growth on the 0.3 ML thick Ga wetting layer. It is shown, that the highest NWs mean elongation rate is obtained with AlN buffer layer, while the lowest elongation rate corresponds to the bare Si (111) surface and it is twice as lower as the first case. It is found, that use of AlN buffer layer corresponds to the most homogeneous NWs array with the smallest length dispersion while the least homogeneous array corresponds to the bare Si substrate. Vertically aligned GaN NWs array on the wide bandgap GaO x semiconductor buffer layer grown by plasma-enhanced chemical vapor deposition demonstrates its potential for electronic applications. Photoluminescence (PL) study of the synthesized samples is characterized by an intense optical response related to the excitons bound to neutral donors. The highest PL intensity is obtained in the sample with AlN buffer layer.

3.
Vestn Ross Akad Med Nauk ; (5): 9-12, 1996.
Artigo em Russo | MEDLINE | ID: mdl-8924831

RESUMO

A hundred and twenty two patients with premature ventricular contractions and paroxysmal tachycardias were comprehensively studied prior to and following treatment regimen with ethacizin, befol, sodium succinate and their combinations. Besides its significant antiarrhythmic activity, ethacizin displayed a number of adverse cardiac effects, such as excessive negative inotropic and dromotropic ones. Befol and sodium succinate in combination with ethacizin can reduce or even eliminate these side effects in rest and during simulated mental stress and graded exercise. The antiarrhythmic effect of the combined therapy preserved or even became stronger. This therapy may be long performed for arrhythmias even in patients with circulatory insufficiency and cardiac conduction disturbances caused or redoubled by ethacizin.


Assuntos
Antiarrítmicos/efeitos adversos , Antidepressivos/administração & dosagem , Arritmias Cardíacas/tratamento farmacológico , Benzamidas/administração & dosagem , Moricizina/análogos & derivados , Morfolinas/administração & dosagem , Succinatos/administração & dosagem , Antiarrítmicos/administração & dosagem , Arritmias Cardíacas/diagnóstico , Quimioterapia Combinada , Eletrocardiografia , Eletrocardiografia Ambulatorial , Moricizina/administração & dosagem , Moricizina/efeitos adversos , Isquemia Miocárdica/complicações , Isquemia Miocárdica/diagnóstico , Ácido Succínico , Taquicardia Paroxística/diagnóstico , Taquicardia Paroxística/tratamento farmacológico , Complexos Ventriculares Prematuros/diagnóstico , Complexos Ventriculares Prematuros/tratamento farmacológico
5.
Bull Exp Biol Med ; 139(3): 322-3, 2005 Mar.
Artigo em Inglês, Russo | MEDLINE | ID: mdl-16027842

RESUMO

Bradysole (1 mg/kg intravenously) induced a moderate increase in cerebral bloodflow and a minor decrease in systemic blood pressure in narcotized rats. These effects were less pronounced compared to the effects of dibasole (bradysole structural analog) in the same dose.


Assuntos
Circulação Cerebrovascular/efeitos dos fármacos , Neurotransmissores/química , Neurotransmissores/farmacologia , Animais , Benzimidazóis/farmacologia , Pressão Sanguínea/efeitos dos fármacos , Pressão Sanguínea/fisiologia , Circulação Cerebrovascular/fisiologia , Relação Dose-Resposta a Droga , Masculino , Ratos , Ratos Wistar , Compostos de Sulfidrila/farmacologia , Fatores de Tempo
6.
Bull Exp Biol Med ; 139(4): 418-20, 2005 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-16027869

RESUMO

We demonstrated a dose-dependent inhibitory effect of novel imidazobenzoimidazole derivatives RU-353 and RU-563 on cerebral blood flow and systemic blood pressure in narcotized rats. The effects of RU-353 increased, while the effect of RU-563 decreased with increasing the dose.


Assuntos
Benzimidazóis/farmacologia , Circulação Cerebrovascular/efeitos dos fármacos , Lidocaína/farmacologia , Animais , Relação Dose-Resposta a Droga , Masculino , Ratos , Ratos Wistar
7.
Bull Exp Biol Med ; 139(5): 569-71, 2005 May.
Artigo em Inglês, Russo | MEDLINE | ID: mdl-16224551

RESUMO

Experiments on rats showed that injection of propranolol into the medulla oblongata increased the contents of epinephrine, norepinephrine, dopamine, and L-DOPA by 3.76, 1.4, 2.0, and 1.7 times, respectively. These propranolol-induced changes in the levels and ratio of neurotransmitters were not accompanied by variations in serotonin content. Propranolol had no significant effects on the content of excitatory amino acids, except marked increase in aspartate content. The level of inhibitory amino acids increased mainly due to an increase in GABA content. The balance between excitatory and inhibitory amino acids was shifted towards inhibitory compounds.


Assuntos
Glândulas Suprarrenais/efeitos dos fármacos , Antagonistas Adrenérgicos beta/farmacologia , Catecolaminas/metabolismo , Bulbo/fisiologia , Propranolol/farmacologia , Sistema Nervoso Simpático/efeitos dos fármacos , Glândulas Suprarrenais/metabolismo , Aminoácidos/metabolismo , Animais , Masculino , Bulbo/efeitos dos fármacos , Distribuição Aleatória , Ratos , Serotonina/metabolismo , Sistema Nervoso Simpático/fisiologia , Ácido gama-Aminobutírico/metabolismo
8.
Bull Exp Biol Med ; 129(5): 460-2, 2000 May.
Artigo em Inglês | MEDLINE | ID: mdl-10977951

RESUMO

The effect of cyclic GABA derivative TZ-146 on the content of catecholamines, serotonin, their metabolites, and neurotransmitter amino acids in rat hypothalamus and brain stem was studied by high-performance liquid chromatography with electrochemical detection. Opposite changes in the content of homovanillic acid, aspartate, glutamate, and glycine in the examined structures were accompanied by inhibition of dopamine metabolism. Possible participation of cerebral glutamatergic system in the effect of TZ-146 is discussed.


Assuntos
Tronco Encefálico/metabolismo , Neurotransmissores/metabolismo , Ácido gama-Aminobutírico/farmacologia , Animais , Ratos , Ratos Wistar , Ácido gama-Aminobutírico/análogos & derivados , Ácido gama-Aminobutírico/metabolismo
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA