Detalhe da pesquisa
1.
Drug delivery to melanoma brain metastases: Can current challenges lead to new opportunities?
Pharmacol Res
; 123: 10-25, 2017 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-28634084
2.
Factors Influencing the Central Nervous System Distribution of a Novel Phosphoinositide 3-Kinase/Mammalian Target of Rapamycin Inhibitor GSK2126458: Implications for Overcoming Resistance with Combination Therapy for Melanoma Brain Metastases.
J Pharmacol Exp Ther
; 356(2): 251-9, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26604245
3.
Factors influencing the CNS distribution of a novel MEK-1/2 inhibitor: implications for combination therapy for melanoma brain metastases.
Drug Metab Dispos
; 42(8): 1292-300, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24875464
4.
Mechanisms limiting distribution of the threonine-protein kinase B-RaF(V600E) inhibitor dabrafenib to the brain: implications for the treatment of melanoma brain metastases.
J Pharmacol Exp Ther
; 344(3): 655-64, 2013 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-23249624
5.
Streamlining Food Effect Assessment - Are Repeated Food Effect Studies Needed? An IQ Analysis.
AAPS J
; 25(4): 60, 2023 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37322223
6.
Impact of P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) on the brain distribution of a novel BRAF inhibitor: vemurafenib (PLX4032).
J Pharmacol Exp Ther
; 342(1): 33-40, 2012 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-22454535
7.
IMI - Oral biopharmaceutics tools project - Evaluation of bottom-up PBPK prediction success part 4: Prediction accuracy and software comparisons with improved data and modelling strategies.
Eur J Pharm Biopharm
; 156: 50-63, 2020 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-32805361
8.
Bioequivalence Comparison of Pediatric Dasatinib Formulations and Elucidation of Absorption Mechanisms Through Integrated PBPK Modeling.
J Pharm Sci
; 108(1): 741-749, 2019 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-30439460
9.
Challenges in the delivery of therapies to melanoma brain metastases.
Curr Pharmacol Rep
; 2(6): 309-325, 2016 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-28546917
10.
Selection of peptide ligands for human placental transcytosis systems using in vitro phage display.
Methods Mol Biol
; 716: 141-56, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21318904