Detalhe da pesquisa
1.
Discovery of cytosine deaminases enables base-resolution methylome mapping using a single enzyme.
Mol Cell
; 84(5): 854-866.e7, 2024 Mar 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38402612
2.
Methyl-SNP-seq reveals dual readouts of methylome and variome at molecule resolution while enabling target enrichment.
Genome Res
; 32(11-12): 2079-2091, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36332968
3.
Nondestructive enzymatic deamination enables single-molecule long-read amplicon sequencing for the determination of 5-methylcytosine and 5-hydroxymethylcytosine at single-base resolution.
Genome Res
; 31(2): 291-300, 2021 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-33468551
4.
Enzymatic methyl sequencing detects DNA methylation at single-base resolution from picograms of DNA.
Genome Res
; 31(7): 1280-1289, 2021 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-34140313
5.
Epigenetic reprogramming enables the transition from primordial germ cell to gonocyte.
Nature
; 555(7696): 392-396, 2018 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29513657
6.
Biochemical characterization of a Naegleria TET-like oxygenase and its application in single molecule sequencing of 5-methylcytosine.
Proc Natl Acad Sci U S A
; 112(14): 4316-21, 2015 Apr 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-25831492
7.
Tissue-specific distribution and dynamic changes of 5-hydroxymethylcytosine in mammalian genomes.
J Biol Chem
; 286(28): 24685-93, 2011 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21610077
8.
Carbamoyltransferase Enzyme Assay: In vitro Modification of 5-hydroxymethylcytosine (5hmC) to 5-carbamoyloxymethylcytosine (5cmC).
Bio Protoc
; 12(17)2022 Sep 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36245800
9.
Detection of TET-Oxidized 5-Methylcytosine Bases by Capillary Gel Electrophoresis.
Methods Mol Biol
; 2198: 137-144, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-32822028
10.
A genome-phenome association study in native microbiomes identifies a mechanism for cytosine modification in DNA and RNA.
Elife
; 102021 11 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34747693
11.
USER friendly DNA engineering and cloning method by uracil excision.
Nucleic Acids Res
; 35(6): 1992-2002, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-17341463
12.
Protein engineering: single or multiple site-directed mutagenesis.
Methods Mol Biol
; 978: 173-86, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23423897
13.
Gene synthesis by assembly of deoxyuridine-containing oligonucleotides.
Methods Mol Biol
; 978: 165-71, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23423896
14.
High sensitivity 5-hydroxymethylcytosine detection in Balb/C brain tissue.
J Vis Exp
; (48)2011 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21307836
15.
The heme biosynthetic pathway of the obligate Wolbachia endosymbiont of Brugia malayi as a potential anti-filarial drug target.
PLoS Negl Trop Dis
; 3(7): e475, 2009 Jul 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-19597542