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Nutrients ; 10(7)2018 Jun 28.
Artigo em Inglês | MEDLINE | ID: mdl-29958393

RESUMO

Maternal diet during pregnancy is relevant for fatty acid supply during fetal life and lactation. Arachidonic (AA) and docosahexaenoic (DHA) acids are also relevant for the normal growth and development of brain and visual system. AA and DHA provided by the mother to the fetus and infant are directly associated with maternal dietary intake and body stores. Our aim was to evaluate the impact of maternal diet, specially referring to the quality of fatty acid intake, in a sample of Chilean women during last stage of pregnancy and across the lactation period. Fifty healthy pregnant women (age range 20⁻33 years) were studied from the 6th month of pregnancy and followed until 6th month of lactation period. Diet characteristics were evaluated through food frequency questionnaires. Fatty acids composition of erythrocyte phospholipids and breast milk samples was assessed by gas-liquid chromatography. Overall, women had high saturated fatty acids intake with sufficient intake of mono- and polyunsaturated fatty acids (PUFA). Diet was high in n-6 PUFA and low in n-3 PUFA (mainly DHA), with imbalanced n-6/n-3 PUFA ratio. Erythrocytes and breast milk DHA concentration was significantly reduced during lactation compared to pregnancy, a pattern not observed for AA. We concluded that is necessary to increase the intake of n-3 PUFA during pregnancy and lactation by improving the quality of consumed foods with particular emphasis on its DHA content.


Assuntos
Dieta , Eritrócitos/metabolismo , Ácidos Graxos/metabolismo , Lactação/metabolismo , Fenômenos Fisiológicos da Nutrição Materna , Leite Humano/metabolismo , Estado Nutricional , Valor Nutritivo , Adulto , Ácido Araquidônico/metabolismo , Chile , Cromatografia Gasosa , Cromatografia Líquida , Dieta/efeitos adversos , Ácidos Docosa-Hexaenoicos/metabolismo , Ingestão de Energia , Ácidos Graxos/sangue , Feminino , Humanos , Lactação/sangue , Avaliação Nutricional , Gravidez , Adulto Jovem
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