Detalhe da pesquisa
1.
Pyroptosis in Alzheimer's disease: cell type-specific activation in microglia, astrocytes and neurons.
Acta Neuropathol
; 145(2): 175-195, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36481964
2.
CRISPR/Cas9 screen in human iPSC-derived cortical neurons identifies NEK6 as a novel disease modifier of C9orf72 poly(PR) toxicity.
Alzheimers Dement
; 19(4): 1245-1259, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35993441
3.
Increased pyroptosis activation in white matter microglia is associated with neuronal loss in ALS motor cortex.
Acta Neuropathol
; 144(3): 393-411, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35867112
4.
HNRNPK alleviates RNA toxicity by counteracting DNA damage in C9orf72 ALS.
Acta Neuropathol
; 144(3): 465-488, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35895140
5.
Necrosome complex detected in granulovacuolar degeneration is associated with neuronal loss in Alzheimer's disease.
Acta Neuropathol
; 139(3): 463-484, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31802237
6.
Dipeptide repeat protein and TDP-43 pathology along the hypothalamic-pituitary axis in C9orf72 and non-C9orf72 ALS and FTLD-TDP cases.
Acta Neuropathol
; 140(5): 777-781, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32862270
7.
An ALS case with 38 (G4C2)-repeats in the C9orf72 gene shows TDP-43 and sparse dipeptide repeat protein pathology.
Acta Neuropathol
; 137(5): 855-858, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30919029
8.
TUBA4A downregulation as observed in ALS post-mortem motor cortex causes ALS-related abnormalities in zebrafish.
Front Cell Neurosci
; 18: 1340240, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38463699
9.
A toxic gain-of-function mechanism in C9orf72 ALS impairs the autophagy-lysosome pathway in neurons.
Acta Neuropathol Commun
; 11(1): 151, 2023 09 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37723585
10.
Frontotemporal Lobar Degeneration Case with an N-Terminal TUBA4A Mutation Exhibits Reduced TUBA4A Levels in the Brain and TDP-43 Pathology.
Biomolecules
; 12(3)2022 03 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35327632
11.
LATE-NC aggravates GVD-mediated necroptosis in Alzheimer's disease.
Acta Neuropathol Commun
; 10(1): 128, 2022 09 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36057624
12.
Distinct molecular patterns of TDP-43 pathology in Alzheimer's disease: relationship with clinical phenotypes.
Acta Neuropathol Commun
; 8(1): 61, 2020 04 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-32349792
13.
TSPO Versus P2X7 as a Target for Neuroinflammation: An In Vitro and In Vivo Study.
J Nucl Med
; 61(4): 604-607, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31562223
14.
Circadian sleep/wake-associated cells show dipeptide repeat protein aggregates in C9orf72-related ALS and FTLD cases.
Acta Neuropathol Commun
; 7(1): 189, 2019 12 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31791419