Detalhe da pesquisa
1.
Histone H3 Dual Ubiquitylation Mediates Maintenance DNA Methylation.
Mol Cell
; 68(2): 261-262, 2017 10 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-29053953
2.
Architecture of PRC2 Holo Complexes.
Trends Biochem Sci
; 43(7): 487-489, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29731341
3.
Searching for methyllysine-binding aromatic cages.
Biochem J
; 478(19): 3613-3619, 2021 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34624071
4.
Topoisomerase II Poisons: Converting Essential Enzymes into Molecular Scissors.
Biochemistry
; 60(21): 1630-1641, 2021 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34008964
5.
Yaf9 subunit of the NuA4 and SWR1 complexes targets histone H3K27ac through its YEATS domain.
Nucleic Acids Res
; 46(1): 421-430, 2018 01 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29145630
6.
Polyamine-containing etoposide derivatives as poisons of human type II topoisomerases: Differential effects on topoisomerase IIα and IIß.
Bioorg Med Chem Lett
; 28(17): 2961-2968, 2018 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30006062
7.
Structural Basis for Sialoglycan Binding by the Streptococcus sanguinis SrpA Adhesin.
J Biol Chem
; 291(14): 7230-40, 2016 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26833566
8.
Effects of Secondary Metabolites from the Fungus Septofusidium berolinense on DNA Cleavage Mediated by Human Topoisomerase IIα.
Chem Res Toxicol
; 29(3): 415-20, 2016 Mar 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-26894873
9.
Inhibition of human DNA topoisomerase IIα by two novel ellipticine derivatives.
Bioorg Med Chem Lett
; 26(7): 1809-12, 2016 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26906637
10.
Effects of Olive Metabolites on DNA Cleavage Mediated by Human Type II Topoisomerases.
Biochemistry
; 54(29): 4531-41, 2015 Jul 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-26132160
11.
Combinatorial inhibition of BTK, PI3K-AKT and BRD4-MYC as a strategy for treatment of mantle cell lymphoma.
Mol Biomed
; 3(1): 2, 2022 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35031886
12.
Binding of the SARS-CoV-2 envelope E protein to human BRD4 is essential for infection.
Structure
; 30(9): 1224-1232.e5, 2022 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35716662
13.
Mechanistic similarities in recognition of histone tails and DNA by epigenetic readers.
Curr Opin Struct Biol
; 71: 1-6, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33993059
14.
The BTK/PI3K/BRD4 axis inhibitor SRX3262 overcomes Ibrutinib resistance in mantle cell lymphoma.
iScience
; 24(9): 102931, 2021 Sep 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-34557659
15.
Blockade of SARS-CoV-2 infection in vitro by highly potent PI3K-α/mTOR/BRD4 inhibitor.
bioRxiv
; 2021 Mar 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33688653
16.
Protocol for Biochemical Analysis and Structure Determination of the ZZ Domain of the E3 Ubiquitin Ligase HERC2.
STAR Protoc
; 1(3): 100155, 2020 12 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-33377049
17.
Structural Insight into Binding of the ZZ Domain of HERC2 to Histone H3 and SUMO1.
Structure
; 28(11): 1225-1230.e3, 2020 11 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32726574
18.
Design of thienopyranone-based BET inhibitors that bind multiple synthetic lethality targets.
Sci Rep
; 10(1): 12027, 2020 07 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32694708
19.
Mechanistic insights into chromatin targeting by leukemic NUP98-PHF23 fusion.
Nat Commun
; 11(1): 3339, 2020 07 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32620764
20.
MORC3 Is a Target of the Influenza A Viral Protein NS1.
Structure
; 27(6): 1029-1033.e3, 2019 06 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31006586