Detalhe da pesquisa
1.
NR1D1 downregulation in astrocytes induces a phenotype that is detrimental to cocultured motor neurons.
FASEB J
; 36(4): e22262, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35319791
2.
Altered expression of clock and clock-controlled genes in a hSOD1-linked amyotrophic lateral sclerosis mouse model.
FASEB J
; 35(2): e21343, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33508151
3.
FABP7 upregulation induces a neurotoxic phenotype in astrocytes.
Glia
; 68(12): 2693-2704, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32619303
4.
Enhanced SIRT6 activity abrogates the neurotoxic phenotype of astrocytes expressing ALS-linked mutant SOD1.
FASEB J
; 33(6): 7084-7091, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30841754
5.
Changes in Protein Expression and Lysine Acetylation Induced by Decreased Glutathione Levels in Astrocytes.
Mol Cell Proteomics
; 15(2): 493-505, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26486419
6.
Enhancing NAD+ Salvage Pathway Reverts the Toxicity of Primary Astrocytes Expressing Amyotrophic Lateral Sclerosis-linked Mutant Superoxide Dismutase 1 (SOD1).
J Biol Chem
; 291(20): 10836-46, 2016 May 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-27002158
7.
NAD+ precursor supplementation modulates neurite complexity and survival in motor neurons from ALS models.
Antioxid Redox Signal
; 2024 Mar 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-38504592
8.
FABP7 drives an inflammatory response in human astrocytes and is upregulated in Alzheimer's disease.
Geroscience
; 46(2): 1607-1625, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-37688656
9.
Astrocyte-specific overexpression of Nrf2 delays motor pathology and synuclein aggregation throughout the CNS in the alpha-synuclein mutant (A53T) mouse model.
J Neurosci
; 32(49): 17775-87, 2012 Dec 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-23223297
10.
Nicotinamide Adenine Dinucleotide (NAD+)-Dependent Signaling in Neurological Disorders.
Antioxid Redox Signal
; 39(16-18): 1150-1166, 2023 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37288742
11.
Nrf2-mediated neuroprotection in the MPTP mouse model of Parkinson's disease: Critical role for the astrocyte.
Proc Natl Acad Sci U S A
; 106(8): 2933-8, 2009 Feb 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-19196989
12.
Decreased glutathione accelerates neurological deficit and mitochondrial pathology in familial ALS-linked hSOD1(G93A) mice model.
Neurobiol Dis
; 43(3): 543-51, 2011 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-21600285
13.
Lead exposure stimulates VEGF expression in the spinal cord and extends survival in a mouse model of ALS.
Neurobiol Dis
; 37(3): 574-80, 2010 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-19914377
14.
Effects of RAGE inhibition on the progression of the disease in hSOD1G93A ALS mice.
Pharmacol Res Perspect
; 8(4): e00636, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32776498
15.
Evaluation of the NAD+ biosynthetic pathway in ALS patients and effect of modulating NAD+ levels in hSOD1-linked ALS mouse models.
Exp Neurol
; 327: 113219, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32014438
16.
Nrf2 activation in astrocytes protects against neurodegeneration in mouse models of familial amyotrophic lateral sclerosis.
J Neurosci
; 28(50): 13574-81, 2008 Dec 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-19074031
17.
The Nrf2-ARE cytoprotective pathway in astrocytes.
Expert Rev Mol Med
; 11: e17, 2009 Jun 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-19490732
18.
Mitochondrial superoxide production and nuclear factor erythroid 2-related factor 2 activation in p75 neurotrophin receptor-induced motor neuron apoptosis.
J Neurosci
; 27(29): 7777-85, 2007 Jul 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-17634371
19.
Transcriptional profile of primary astrocytes expressing ALS-linked mutant SOD1.
J Neurosci Res
; 86(16): 3515-25, 2008 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-18683239
20.
Redox Biology in Neurological Function, Dysfunction, and Aging.
Antioxid Redox Signal
; 28(18): 1583-1586, 2018 06 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-29634346