Detalhe da pesquisa
1.
Discovery of 1,3-disubstituted pyrazole peripheral cannabinoid receptor partial agonists.
Bioorg Med Chem Lett
; 93: 129430, 2023 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37543275
2.
Synthesis and characterization of an orally bioavailable small molecule agonist of the apelin receptor.
Bioorg Med Chem
; 66: 116789, 2022 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35594649
3.
Structure-Activity Relationship Development Efforts towards Peripherally Selective Analogs of the Cannabinoid Receptor Partial Agonist BAY 59-3074.
Molecules
; 27(17)2022 Sep 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36080443
4.
Identification of potent pyrazole based APELIN receptor (APJ) agonists.
Bioorg Med Chem
; 28(4): 115237, 2020 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31948845
5.
Functionalized 6-(piperidin-1-yl)-8,9-diphenyl purines as inverse agonists of the CB1 receptor - SAR efforts towards selectivity and peripheralization.
Bioorg Med Chem
; 27(16): 3632-3649, 2019 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31301950
6.
Synthesis and pharmacological characterization of functionalized 6-piperazin-1-yl-purines as cannabinoid receptor 1 (CB1) inverse agonists.
Bioorg Med Chem
; 26(15): 4518-4531, 2018 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30077609
7.
Discovery of a novel small molecule agonist scaffold for the APJ receptor.
Bioorg Med Chem
; 24(16): 3758-70, 2016 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27369451
8.
Discovery and Characterization of the First Nonpeptide Antagonists for the Relaxin-3/RXFP3 System.
J Med Chem
; 65(11): 7959-7974, 2022 06 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35594150
9.
Indole-Containing Amidinohydrazones as Nonpeptide, Dual RXFP3/4 Agonists: Synthesis, Structure-Activity Relationship, and Molecular Modeling Studies.
J Med Chem
; 64(24): 17866-17886, 2021 12 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-34855388
10.
Pyrazole Agonist of the Apelin Receptor Improves Symptoms of Metabolic Syndrome in Mice.
J Med Chem
; 64(6): 3006-3025, 2021 03 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-33705126
11.
Functionalized 6-(Piperidin-1-yl)-8,9-Diphenyl Purines as Peripherally Restricted Inverse Agonists of the CB1 Receptor.
J Med Chem
; 62(13): 6330-6345, 2019 07 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31185168
12.
Blocking Alcoholic Steatosis in Mice with a Peripherally Restricted Purine Antagonist of the Type 1 Cannabinoid Receptor.
J Med Chem
; 61(10): 4370-4385, 2018 05 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-29688015