Detalhe da pesquisa
1.
New Positive TRPC6 Modulator Penetrates Blood-Brain Barrier, Eliminates Synaptic Deficiency and Restores Memory Deficit in 5xFAD Mice.
Int J Mol Sci
; 23(21)2022 Nov 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36362339
2.
Mechanism of the Affinity-Enhancing Effect of Isatin on Human Ferrochelatase and Adrenodoxin Reductase Complex Formation: Implication for Protein Interactome Regulation.
Int J Mol Sci
; 21(20)2020 Oct 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-33066693
3.
Spatial features of proteins related to their phosphorylation and associated structural changes.
Proteins
; 86(1): 13-20, 2018 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-28986918
4.
An investigation of the monoamine oxidase inhibition properties of pyrrolo[3,4-f]indole-5,7-dione and indole-5,6-dicarbonitrile derivatives.
Drug Dev Res
; 79(2): 81-93, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29570223
5.
Prediction of amino acid positions specific for functional groups in a protein family based on local sequence similarity.
J Mol Recognit
; 29(4): 159-69, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26549790
6.
Computer-aided design of aptamers for cytochrome p450.
J Struct Biol
; 191(2): 112-9, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-26166326
7.
Prediction of amino acid residues participated in substrate recognition by cytochrome P450 subfamilies with broad substrate specificity.
J Mol Recognit
; 26(2): 86-91, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23334916
8.
AliNA - a deep learning program for RNA secondary structure prediction.
Mol Inform
; 42(12): e202300113, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37710142
9.
Oxazolinyl derivatives of androst-16-ene as inhibitors of CYP17A1 activity and prostate carcinoma cells proliferation: Effects of substituents in oxazolinyl moiety.
J Steroid Biochem Mol Biol
; 230: 106280, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36870373
10.
Approaches for increasing the electrocatalitic efficiency of cytochrome P450 3A4.
Bioelectrochemistry
; 149: 108277, 2023 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-36198256
11.
New Genetic Bomb Trigger: Design, Synthesis, Molecular Dynamics Simulation, and Biological Evaluation of Novel BIBR1532-Related Analogs Targeting Telomerase against Non-Small Cell Lung Cancer.
Pharmaceuticals (Basel)
; 15(4)2022 Apr 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-35455478
12.
The Introduction of Hydrazone, Hydrazide, or Azepane Moieties to the Triterpenoid Core Enhances an Activity Against M. tuberculosis.
Med Chem
; 17(2): 134-145, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-31939731
13.
Interactions of galeterone and its 3-keto-Δ4 metabolite (D4G) with one of the key enzymes of corticosteroid biosynthesis - steroid 21-monooxygenase (CYP21A2).
Fundam Clin Pharmacol
; 35(2): 423-431, 2021 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-33012006
14.
Mechanisms of the Antiproliferative and Antitumor Activity of Novel Telomerase-Carbonic Anhydrase Dual-Hybrid Inhibitors.
J Med Chem
; 64(15): 11432-11444, 2021 08 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34283610
15.
The interactions of a number of steroid-metabolizing cytochromes P450 with abiraterone D4A metabolite: spectral analysis and molecular docking.
Steroids
; 162: 108693, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32645328
16.
New steroidal oxazolines, benzoxazoles and benzimidazoles related to abiraterone and galeterone.
Steroids
; 153: 108534, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31678134
17.
In vitro interactions of abiraterone, erythromycin, and CYP3A4: implications for drug-drug interactions.
Fundam Clin Pharmacol
; 34(1): 120-130, 2020 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-31286572
18.
N-domain of angiotensin-converting enzyme hydrolyzes human and rat amyloid-ß(1-16) peptides as arginine specific endopeptidase potentially enhancing risk of Alzheimer's disease.
Sci Rep
; 8(1): 298, 2018 01 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29321566
19.
Epitope mapping of the domains of human angiotensin converting enzyme.
Biochim Biophys Acta
; 1760(6): 959-65, 2006 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-16580777
20.
Bioinformatics platform development: from gene to lead compound.
Methods Mol Biol
; 316: 389-431, 2006.
Artigo
em Inglês
| MEDLINE | ID: mdl-16671411