Detalhe da pesquisa
1.
A Subset of Type I Conventional Dendritic Cells Controls Cutaneous Bacterial Infections through VEGFα-Mediated Recruitment of Neutrophils.
Immunity
; 50(4): 1069-1083.e8, 2019 04 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-30926233
2.
Brimonidine displays anti-inflammatory properties in the skin through the modulation of the vascular barrier function.
Exp Dermatol
; 27(12): 1378-1387, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30290018
3.
Sulfoximines as potent RORγ inverse agonists.
Bioorg Med Chem Lett
; 28(8): 1269-1273, 2018 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29571573
4.
Discovery and process development of a novel TACE inhibitor for the topical treatment of psoriasis.
Bioorg Med Chem
; 26(4): 945-956, 2018 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28818461
5.
Smurf1 regulates tumor cell plasticity and motility through degradation of RhoA leading to localized inhibition of contractility.
J Cell Biol
; 176(1): 35-42, 2007 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17190792
6.
ERK-MAPK signaling coordinately regulates activity of Rac1 and RhoA for tumor cell motility.
Cancer Cell
; 4(1): 67-79, 2003 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-12892714
7.
Impact of Minor Structural Modifications on Properties of a Series of mTOR Inhibitors.
ACS Med Chem Lett
; 10(11): 1561-1567, 2019 Nov 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-31749911
8.
Major contribution of MEK1 to the activation of ERK1/ERK2 and to the growth of LS174T colon carcinoma cells.
Biochem Biophys Res Commun
; 372(4): 845-9, 2008 Aug 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-18533112
9.
Discovery and Characterization of CD12681, a Potent RORγ Inverse Agonist, Preclinical Candidate for the Topical Treatment of Psoriasis.
ChemMedChem
; 13(4): 321-337, 2018 02 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-29327456
10.
v-Jun downregulates the SPARC target gene by binding to the proximal promoter indirectly through Sp1/3.
Oncogene
; 22(26): 4047-61, 2003 Jun 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-12821939
11.
Protective Effect of Dermal Brimonidine Applications Against UV Radiation-induced Skin Tumors, Epidermal Hyperplasia and Cell Proliferation in the Skin of Hairless Mice.
Photochem Photobiol
; 91(6): 1479-87, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26333507
12.
Combining two repurposed drugs as a promising approach for Alzheimer's disease therapy.
Sci Rep
; 5: 7608, 2015 Jan 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-25566747
13.
Polytherapy with a combination of three repurposed drugs (PXT3003) down-regulates Pmp22 over-expression and improves myelination, axonal and functional parameters in models of CMT1A neuropathy.
Orphanet J Rare Dis
; 9: 201, 2014 Dec 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-25491744
14.
Elevated ERK-MAP kinase activity protects the FOS family member FRA-1 against proteasomal degradation in colon carcinoma cells.
J Cell Sci
; 116(Pt 24): 4957-63, 2003 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-14625389