RESUMO
OBJECTIVE: To evaluate the safety and efficacy of mechanical thrombectomy associated with standard medical treatment compared with standard medical treatment only to treat patients with acute ischemic stroke. METHODS: This was a systematic review and metaanalysis of randomized controlled trials. An electronic search was performed in the following databases: MEDLINE ® /PubMed ® , Cochrane Library (Trials), LILACS/IBECS (via Biblioteca Virtual em Saúde (BVS)) and Embase. Complementary searches were also conducted. The selection of studies and data collection were done by two investigators independently. RESULTS: The final analysis included 16 publications related to 15 studies. The mechanical thrombectomy was associated to a reduction in the risk of death of all cause (16.81% versus 20.13%; relative risk of 0.85; p=0.04), improvement in the number of patients with functional independence after 90 days (45.65% versus 27.45%; relative risk of 1.65; p<0.01), and improvement in the rate of revascularization (76.2% versus 33.85%; relative risk of 2.20; p<0.01). There was no significant difference in terms of symptomatic intracranial hemorrhage (4.78% versus 3.88%; relative risk of 1.27; p=0.21). CONCLUSION: Mechanical thrombectomy associated with standard medical treatment seem to be safe and effective to treat patients with acute ischemic stroke compared with standard medical treatment only.
Assuntos
Isquemia Encefálica , Procedimentos Endovasculares , AVC Isquêmico , Acidente Vascular Cerebral , Isquemia Encefálica/complicações , Isquemia Encefálica/terapia , Procedimentos Endovasculares/efeitos adversos , Humanos , AVC Isquêmico/cirurgia , Acidente Vascular Cerebral/complicações , Acidente Vascular Cerebral/terapia , Trombectomia/efeitos adversos , Resultado do TratamentoRESUMO
ABSTRACT Objective To evaluate the safety and efficacy of mechanical thrombectomy associated with standard medical treatment compared with standard medical treatment only to treat patients with acute ischemic stroke. Methods This was a systematic review and metaanalysis of randomized controlled trials. An electronic search was performed in the following databases: MEDLINE ® /PubMed ® , Cochrane Library (Trials), LILACS/IBECS (via Biblioteca Virtual em Saúde (BVS)) and Embase. Complementary searches were also conducted. The selection of studies and data collection were done by two investigators independently. Results The final analysis included 16 publications related to 15 studies. The mechanical thrombectomy was associated to a reduction in the risk of death of all cause (16.81% versus 20.13%; relative risk of 0.85; p=0.04), improvement in the number of patients with functional independence after 90 days (45.65% versus 27.45%; relative risk of 1.65; p<0.01), and improvement in the rate of revascularization (76.2% versus 33.85%; relative risk of 2.20; p<0.01). There was no significant difference in terms of symptomatic intracranial hemorrhage (4.78% versus 3.88%; relative risk of 1.27; p=0.21). Conclusion Mechanical thrombectomy associated with standard medical treatment seem to be safe and effective to treat patients with acute ischemic stroke compared with standard medical treatment only.
RESUMO
RESUMO O presente estudo teve por objetivo descrever a experiência de implantação do Projeto de Extensão Gestão e Gentileza nos plantões noturnos de um hospital universitário, de janeiro a dezembro de 2017, explicitando a articulação entre o conhecimento teórico adquirido em diversas disciplinas do Curso de Gestão de Serviços de Saúde e a prática extensionista. O projeto, direcionado aos trabalhadores noturnos, buscou ressaltar a importância desses funcionários no ambiente hospitalar por meio de intervenções de gestão e gentileza em sete unidades do Hospital. A articulação entre teoria e prática perpassou pelas diversas etapas do projeto, contribuindo para a formação de profissionais capazes de intervir no cotidiano das organizações de saúde de maneira inovadora e efetiva. A vivência no projeto certificou a urgência de pensar intervenções permeadas por ações de gentileza em que todos os profissionais tenham condições de participar e se beneficiar com os resultados.
ABSTRACT The present study aims to describe the experience of implementing the Extension Project Management and Kindness in the night shifts of a university hospital, from January to December 2017, showing the articulation between the theoretical knowledge acquired in several subjects of the Health Services Management Course and the extension practice. The project, aimed at night workers, sought to highlight their importance in the hospital environment by means of management and kindness in seven hospital units. The articulation between theory and practice permeated the various stages of the project, contributing to the formation of professionals capable of intervening in the daily life of health organizations in an innovative and effective way. The experience in the project certified the urgency to think of interventions permeated by actions of kindness in which all professionals are able to participate and benefit from the results.