Detalhe da pesquisa
1.
Delivery of Anticancer Drugs Using Microbubble-Assisted Ultrasound in a 3D Spheroid Model.
Mol Pharm
; 21(2): 831-844, 2024 Feb 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38174896
2.
Therapeutic Potential of MF-TTZ-MMAE, a Site-Specifically Conjugated Antibody-Drug Conjugate, for the Treatment of HER2-Overexpressing Breast Cancer.
Bioconjug Chem
; 33(2): 418-426, 2022 02 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-35104102
3.
Innovative Bioconjugation Technology for Antibody-Drug Conjugates: Proof of Concept in a CD30-Positive Lymphoma Mouse Model.
Bioconjug Chem
; 32(3): 595-606, 2021 03 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-33630573
4.
Design, synthesis, and antiproliferative effect of 2,9-bis[4-(pyridinylalkylaminomethyl)phenyl]-1,10-phenanthroline derivatives on human leukemic cells by targeting G-quadruplex.
Arch Pharm (Weinheim)
; 354(8): e2000450, 2021 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-33852185
5.
Pharmacological Characterization of Low Molecular Weight Biased Agonists at the Follicle Stimulating Hormone Receptor.
Int J Mol Sci
; 22(18)2021 Sep 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34576014
6.
New Quinoxaline Derivatives as Dual Pim-1/2 Kinase Inhibitors: Design, Synthesis and Biological Evaluation.
Molecules
; 26(4)2021 Feb 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33562106
7.
S29434, a Quinone Reductase 2 Inhibitor: Main Biochemical and Cellular Characterization.
Mol Pharmacol
; 95(3): 269-285, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30567956
8.
Consequences of cathepsin C inactivation for membrane exposure of proteinase 3, the target antigen in autoimmune vasculitis.
J Biol Chem
; 293(32): 12415-12428, 2018 08 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29925593
9.
Site-Specific Conjugation of Auristatins onto Engineered scFv Using Second Generation Maleimide to Target HER2-positive Breast Cancer in Vitro.
Bioconjug Chem
; 29(11): 3516-3521, 2018 11 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-30352511
10.
Impact of Site-Specific Conjugation of ScFv to Multifunctional Nanomedicines Using Second Generation Maleimide.
Bioconjug Chem
; 29(5): 1553-1559, 2018 05 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-29553717
11.
Impact of cathepsin B-sensitive triggers and hydrophilic linkers on in vitro efficacy of novel site-specific antibody-drug conjugates.
Org Biomol Chem
; 16(11): 1882-1889, 2018 03 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-29473076
12.
Increment in Drug Loading on an Antibody-Drug Conjugate Increases Its Binding to the Human Neonatal Fc Receptor in Vitro.
Mol Pharm
; 13(4): 1405-12, 2016 Apr 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-26900766
13.
Rhodium-catalyzed 1,4-addition of arylboronic acids to 3-benzylidene-1H-pyrrolo[2,3-b]pyridin-2(3H)-one derivatives.
J Org Chem
; 80(6): 3264-9, 2015 Mar 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-25689109
14.
Antibody-Drug Conjugates as an Emerging Therapy in Oncodermatology.
Cancers (Basel)
; 14(3)2022 Feb 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35159045
15.
Dual intra- and extracellular release of monomethyl auristatin E from a neutrophil elastase-sensitive antibody-drug conjugate.
Eur J Med Chem
; 229: 114063, 2022 Feb 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34974337
16.
Anticalin N- or C-Terminal on a Monoclonal Antibody Affects Both Production and In Vitro Functionality.
Antibodies (Basel)
; 11(3)2022 Aug 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-35997348
17.
Design, synthesis and biological evaluation of new thalidomide analogues as TNF-α and IL-6 production inhibitors.
Bioorg Med Chem Lett
; 21(3): 1019-22, 2011 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21215621
18.
Inhibitors Targeting STAT5 Signaling in Myeloid Leukemias: New Tetrahydroquinoline Derivatives with Improved Antileukemic Potential.
ChemMedChem
; 16(6): 1034-1046, 2021 03 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-33275308
19.
Correction to Rhodium-Catalyzed 1,4-Addition of Arylboronic Acids to 3-Benzylidene-1H-pyrrolo[2,3-b]pyridin-2(3H)-one Derivatives.
J Org Chem
; 80(11): 5999, 2015 Jun 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-25961809
20.
Uncyclized xanthommatin is a key ommochrome intermediate in invertebrate coloration.
Insect Biochem Mol Biol
; 124: 103403, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32574597