Detalhe da pesquisa
1.
Unraveling the complexity of amyloid polymorphism using gold nanoparticles and cryo-EM.
Proc Natl Acad Sci U S A
; 117(12): 6866-6874, 2020 03 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-32161130
2.
PINK1-dependent phosphorylation of Serine111 within the SF3 motif of Rab GTPases impairs effector interactions and LRRK2-mediated phosphorylation at Threonine72.
Biochem J
; 477(9): 1651-1668, 2020 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32227113
3.
Phosphorylation of Ser111 in Rab8a Modulates Rabin8-Dependent Activation by Perturbation of Side Chain Interaction Networks.
Biochemistry
; 58(33): 3546-3554, 2019 08 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-31361120
4.
An Intein-based Strategy for the Production of Tag-free Huntingtin Exon 1 Proteins Enables New Insights into the Polyglutamine Dependence of Httex1 Aggregation and Fibril Formation.
J Biol Chem
; 291(23): 12074-86, 2016 Jun 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-27002149
5.
Mutant Exon1 Huntingtin Aggregation is Regulated by T3 Phosphorylation-Induced Structural Changes and Crosstalk between T3 Phosphorylation and Acetylation at K6.
Angew Chem Int Ed Engl
; 56(19): 5202-5207, 2017 05 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28334491
6.
The Nt17 Domain and its Helical Conformation Regulate the Aggregation, Cellular Properties and Neurotoxicity of Mutant Huntingtin Exon 1.
J Mol Biol
; 433(21): 167222, 2021 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34492254
7.
Locking GTPases covalently in their functional states.
Nat Commun
; 6: 7773, 2015 Jul 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-26178622