Detalhe da pesquisa
1.
Mapping genomic loci implicates genes and synaptic biology in schizophrenia.
Nature
; 604(7906): 502-508, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35396580
2.
Transcriptome-wide association study in UK Biobank Europeans identifies associations with blood cell traits.
Hum Mol Genet
; 31(14): 2333-2347, 2022 07 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-35138379
3.
Convergence of the dysregulated regulome in schizophrenia with polygenic risk and evolutionarily constrained enhancers.
Mol Psychiatry
; 2023 Dec 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-38145985
4.
PS1 FAD mutants decrease ephrinB2-regulated angiogenic functions, ischemia-induced brain neovascularization and neuronal survival.
Mol Psychiatry
; 26(6): 1996-2012, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32541930
5.
Open chromatin profiling of human postmortem brain infers functional roles for non-coding schizophrenia loci.
Hum Mol Genet
; 26(10): 1942-1951, 2017 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28335009
6.
Presenilin1/γ-secretase protects neurons from glucose deprivation-induced death by regulating miR-212 and PEA15.
FASEB J
; 32(1): 243-253, 2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28855274
7.
The product of the γ-secretase processing of ephrinB2 regulates VE-cadherin complexes and angiogenesis.
Cell Mol Life Sci
; 75(15): 2813-2826, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29428965
8.
Presenilin 1 is necessary for neuronal, but not glial, EGFR expression and neuroprotection via γ-secretase-independent transcriptional mechanisms.
FASEB J
; 29(9): 3702-12, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-25985800
9.
A critical role for human caspase-4 in endotoxin sensitivity.
J Immunol
; 193(1): 335-43, 2014 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24879791
10.
Open chromatin profiling of human postmortem brain infers functional roles for non-coding schizophrenia loci.
Hum Mol Genet
; 2018 Jun 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-29982455
11.
Alzheimer's disease transcriptional landscape in ex-vivo human microglia.
Res Sq
; 2024 Jan 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-38343831
12.
Genome-Wide Association Study of Treatment-Resistant Depression: Shared Biology With Metabolic Traits.
Am J Psychiatry
; : appiajp20230247, 2024 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38745458
13.
Detecting and Adjusting for Hidden Biases due to Phenotype Misclassification in Genome-Wide Association Studies.
medRxiv
; 2023 Jan 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-36711948
14.
Efficient differential expression analysis of large-scale single cell transcriptomics data using dreamlet.
bioRxiv
; 2023 Mar 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-36993704
15.
Efficient differential expression analysis of large-scale single cell transcriptomics data using dreamlet.
Res Sq
; 2023 May 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37205331
16.
Genome-wide analysis of a model-derived binge eating disorder phenotype identifies risk loci and implicates iron metabolism.
Nat Genet
; 55(9): 1462-1470, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37550530
17.
The neuronal chromatin landscape in adult schizophrenia brains is linked to early fetal development.
Res Sq
; 2023 Oct 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37886514
18.
The neuronal chromatin landscape in adult schizophrenia brains is linked to early fetal development.
medRxiv
; 2023 Oct 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-37873320
19.
Genome-wide association study of school grades identifies genetic overlap between language ability, psychopathology and creativity.
Sci Rep
; 13(1): 429, 2023 01 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36624241
20.
Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains.
Nat Genet
; 55(2): 198-208, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36702997