Detalhe da pesquisa
1.
Allosteric activation of VCP, an AAA unfoldase, by small molecule mimicry.
Proc Natl Acad Sci U S A
; 121(24): e2316892121, 2024 Jun 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38833472
2.
Using a Function-First "Scout Fragment"-Based Approach to Develop Allosteric Covalent Inhibitors of Conformationally Dynamic Helicase Mechanoenzymes.
J Am Chem Soc
; 146(1): 62-67, 2024 Jan 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-38134034
3.
Differential effects of disulfide bond formation in TEM-1 versus CTX-M-9 ß-lactamase.
Protein Sci
; 33(1): e4816, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-37897253
4.
Fine-tuning chemical genetics to identify physiologic drug targets.
Cell Chem Biol
; 30(11): 1331-1333, 2023 11 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-37977127
5.
Using a function-first 'scout fragment'-based approach to develop allosteric covalent inhibitors of conformationally dynamic helicase mechanoenzymes.
bioRxiv
; 2023 Sep 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-37808863
6.
Caspase-1 interdomain linker cleavage is required for pyroptosis.
Life Sci Alliance
; 3(3)2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32051255