Detalhe da pesquisa
1.
Hepatoprotective effects of the long-acting fibroblast growth factor 21 analog PF-05231023 in the GAN diet-induced obese and biopsy-confirmed mouse model of nonalcoholic steatohepatitis.
Am J Physiol Gastrointest Liver Physiol
; 324(5): G378-G388, 2023 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36852934
2.
Therapeutic effects of lisinopril and empagliflozin in a mouse model of hypertension-accelerated diabetic kidney disease.
Am J Physiol Renal Physiol
; 321(2): F149-F161, 2021 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34180715
3.
Whole-brain mapping of amylin-induced neuronal activity in receptor activity-modifying protein 1/3 knockout mice.
Eur J Neurosci
; 2021 Apr 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-33905587
4.
An Aldehyde Responsive, Cleavable Linker for Glucose Responsive Insulins.
Chemistry
; 27(9): 3166-3176, 2021 Feb 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33169429
5.
Human translatability of the GAN diet-induced obese mouse model of non-alcoholic steatohepatitis.
BMC Gastroenterol
; 20(1): 210, 2020 Jul 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32631250
6.
Hepatic transcriptome signatures in patients with varying degrees of nonalcoholic fatty liver disease compared with healthy normal-weight individuals.
Am J Physiol Gastrointest Liver Physiol
; 316(4): G462-G472, 2019 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30653341
7.
Validity of biopsy-based drug effects in a diet-induced obese mouse model of biopsy-confirmed NASH.
BMC Gastroenterol
; 19(1): 228, 2019 Dec 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-31883514
8.
Disease Progression and Pharmacological Intervention in a Nutrient-Deficient Rat Model of Nonalcoholic Steatohepatitis.
Dig Dis Sci
; 64(5): 1238-1256, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30511198
9.
Neoglycolipids for Prolonging the Effects of Peptides: Self-Assembling Glucagon-like Peptide 1 Analogues with Albumin Binding Properties and Potent in Vivo Efficacy.
Mol Pharm
; 14(1): 193-205, 2017 01 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28005376
10.
GUB06-046, a novel secretin/glucagon-like peptide 1 co-agonist, decreases food intake, improves glycemic control, and preserves beta cell mass in diabetic mice.
J Pept Sci
; 23(12): 845-854, 2017 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-29057588
11.
Synthesis and evaluation of novel lipidated neuromedin U analogs with increased stability and effects on food intake.
J Pept Sci
; 21(2): 85-94, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25521062
12.
The novel GLP-1-gastrin dual agonist ZP3022 improves glucose homeostasis and increases ß-cell mass without affecting islet number in db/db mice.
J Pharmacol Exp Ther
; 350(2): 353-60, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24902584
13.
The sodium glucose cotransporter type 2 inhibitor empagliflozin preserves ß-cell mass and restores glucose homeostasis in the male zucker diabetic fatty rat.
J Pharmacol Exp Ther
; 350(3): 657-64, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-24993361
14.
Identification of GDF15 peptide fragments inhibiting GFRAL receptor signaling.
Peptides
; 168: 171063, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37495041
15.
The effects of 13 wk of liraglutide treatment on endocrine and exocrine pancreas in male and female ZDF rats: a quantitative and qualitative analysis revealing no evidence of drug-induced pancreatitis.
Am J Physiol Endocrinol Metab
; 303(2): E253-64, 2012 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22589391
16.
Improving membrane binding as a design strategy for amphipathic peptide hormones: 2-helix variants of PYY3-36.
J Pept Sci
; 18(9): 579-87, 2012 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-22865741
17.
Effects of liraglutide and sibutramine on food intake, palatability, body weight and glucose tolerance in the gubra DIO-rats.
Acta Pharmacol Sin
; 33(2): 194-200, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-22301859
18.
Hepatoprotective effects of semaglutide, lanifibranor and dietary intervention in the GAN diet-induced obese and biopsy-confirmed mouse model of NASH.
Clin Transl Sci
; 15(5): 1167-1186, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35143711
19.
Lipidated PrRP31 metabolites are long acting dual GPR10 and NPFF2 receptor agonists with potent body weight lowering effect.
Sci Rep
; 12(1): 1696, 2022 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35105898
20.
Rodent models of diabetic kidney disease: human translatability and preclinical validity.
Drug Discov Today
; 26(1): 200-217, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32413492