Detalhe da pesquisa
1.
Orally Bioavailable Macrocyclic Peptide That Inhibits Binding of PCSK9 to the Low Density Lipoprotein Receptor.
Circulation
; 148(2): 144-158, 2023 07 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37125593
2.
Direct and enantioselective {alpha}-allylation of ketones via singly occupied molecular orbital (SOMO) catalysis.
Proc Natl Acad Sci U S A
; 107(48): 20648-51, 2010 Nov 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-20921367
3.
Cycle-specific organocascade catalysis: application to olefin hydroamination, hydro-oxidation, and amino-oxidation, and to natural product synthesis.
Angew Chem Int Ed Engl
; 48(24): 4349-53, 2009.
Artigo
em Inglês
| MEDLINE | ID: mdl-19434637
4.
Preclinical Characterization of 18F-MK-6240, a Promising PET Tracer for In Vivo Quantification of Human Neurofibrillary Tangles.
J Nucl Med
; 57(10): 1599-1606, 2016 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-27230925
5.
Discovery of 6-(Fluoro-(18)F)-3-(1H-pyrrolo[2,3-c]pyridin-1-yl)isoquinolin-5-amine ([(18)F]-MK-6240): A Positron Emission Tomography (PET) Imaging Agent for Quantification of Neurofibrillary Tangles (NFTs).
J Med Chem
; 59(10): 4778-89, 2016 05 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-27088900
6.
Universal strategy for the immobilization of chiral dirhodium catalysts.
Org Lett
; 7(14): 2941-4, 2005 Jul 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-15987175
7.
Discovery of MK-8970: an acetal carbonate prodrug of raltegravir with enhanced colonic absorption.
ChemMedChem
; 10(2): 245-52, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25469982
8.
Discovery of 2-Pyridinone Aminals: A Prodrug Strategy to Advance a Second Generation of HIV-1 Integrase Strand Transfer Inhibitors.
J Med Chem
; 58(20): 8154-65, 2015 Oct 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-26397965
9.
Asymmetric intermolecular C-H activation, using immobilized dirhodium tetrakis((S)-N-(dodecylbenzenesulfonyl)- prolinate) as a recoverable catalyst.
Org Lett
; 5(4): 479-82, 2003 Feb 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-12583748
10.
Correction to Discovery of 2-Pyridinone Aminals: A Prodrug Strategy to Advance a Second Generation of HIV-1 Integrase Strand Transfer Inhibitors.
J Med Chem
; 59(1): 486, 2016 Jan 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-26709958
11.
Direct synthesis of (+)-erogorgiaene through a kinetic enantiodifferentiating step.
Angew Chem Int Ed Engl
; 44(11): 1733-5, 2005 Mar 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-15712310
12.
Enantioselective organocatalytic transfer hydrogenation reactions using Hantzsch esters.
Acc Chem Res
; 40(12): 1327-39, 2007 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-18085748
13.
Strategies towards improving the pharmacokinetic profile of ε-substituted lysinol-derived HIV protease inhibitors.
ChemMedChem
; 6(2): 253-7, 2011 Feb 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-21275047
14.
Enantioselective organo-cascade catalysis.
J Am Chem Soc
; 127(43): 15051-3, 2005 Nov 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-16248643
15.
Simple strategy for the immobilization of dirhodium tetraprolinate catalysts using a pyridine-linked solid support.
J Am Chem Soc
; 126(13): 4271-80, 2004 Apr 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-15053617