Pesquisa | Portal de Pesquisa da BVS

1.

ADAR1p150 prevents MDA5 and PKR activation via distinct mechanisms to avert fatal autoinflammation.

Hu, Shi-Bin; Heraud-Farlow, Jacki; Sun, Tao; Liang, Zhen; Goradia, Ankita; Taylor, Scott; Walkley, Carl R; Li, Jin Billy.

Mol Cell ; 83(21): 3869-3884.e7, 2023 Nov 02.

Artigo em Inglês | MEDLINE | ID: mdl-37797622

2.

ADAR1 masks the cancer immunotherapeutic promise of ZBP1-driven necroptosis.

Zhang, Ting; Yin, Chaoran; Fedorov, Aleksandr; Qiao, Liangjun; Bao, Hongliang; Beknazarov, Nazar; Wang, Shiyu; Gautam, Avishekh; Williams, Riley M; Crawford, Jeremy Chase; Peri, Suraj; Studitsky, Vasily; Beg, Amer A; Thomas, Paul G; Walkley, Carl; Xu, Yan; Poptsova, Maria; Herbert, Alan; Balachandran, Siddharth.

Nature ; 606(7914): 594-602, 2022 06.

Artigo em Inglês | MEDLINE | ID: mdl-35614224

3.

Direct identification of A-to-I editing sites with nanopore native RNA sequencing.

Nguyen, Tram Anh; Heng, Jia Wei Joel; Kaewsapsak, Pornchai; Kok, Eng Piew Louis; Stanojevic, Dominik; Liu, Hao; Cardilla, Angelysia; Praditya, Albert; Yi, Zirong; Lin, Mingwan; Aw, Jong Ghut Ashley; Ho, Yin Ying; Peh, Kai Lay Esther; Wang, Yuanming; Zhong, Qixing; Heraud-Farlow, Jacki; Xue, Shifeng; Reversade, Bruno; Walkley, Carl; Ho, Ying Swan; Sikic, Mile; Wan, Yue; Tan, Meng How.

Nat Methods ; 19(7): 833-844, 2022 07.

Artigo em Inglês | MEDLINE | ID: mdl-35697834

4.

Generation of a new Adar1p150 ^-/- mouse demonstrates isoform-specific roles in embryonic development and adult homeostasis.

Liang, Zhen; Goradia, Ankita; Walkley, Carl R; Heraud-Farlow, Jacki E.

RNA ; 29(9): 1325-1338, 2023 09.

Artigo em Inglês | MEDLINE | ID: mdl-37290963

5.

The phenotype of the most common human ADAR1p150 Zα mutation P193A in mice is partially penetrant.

Liang, Zhen; Chalk, Alistair M; Taylor, Scott; Goradia, Ankita; Heraud-Farlow, Jacki E; Walkley, Carl R.

EMBO Rep ; 24(5): e55835, 2023 05 04.

Artigo em Inglês | MEDLINE | ID: mdl-36975179

6.

Dynamic landscape and regulation of RNA editing in mammals.

Tan, Meng How; Li, Qin; Shanmugam, Raghuvaran; Piskol, Robert; Kohler, Jennefer; Young, Amy N; Liu, Kaiwen Ivy; Zhang, Rui; Ramaswami, Gokul; Ariyoshi, Kentaro; Gupte, Ankita; Keegan, Liam P; George, Cyril X; Ramu, Avinash; Huang, Ni; Pollina, Elizabeth A; Leeman, Dena S; Rustighi, Alessandra; Goh, Y P Sharon; Chawla, Ajay; Del Sal, Giannino; Peltz, Gary; Brunet, Anne; Conrad, Donald F; Samuel, Charles E; O'Connell, Mary A; Walkley, Carl R; Nishikura, Kazuko; Li, Jin Billy.

Nature ; 550(7675): 249-254, 2017 10 11.

Artigo em Inglês | MEDLINE | ID: mdl-29022589

7.

ATP-dependent helicase activity is dispensable for the physiological functions of Recql4.

Castillo-Tandazo, Wilson; Smeets, Monique F; Murphy, Vincent; Liu, Rui; Hodson, Charlotte; Heierhorst, Jörg; Deans, Andrew J; Walkley, Carl R.

PLoS Genet ; 15(7): e1008266, 2019 07.

Artigo em Inglês | MEDLINE | ID: mdl-31276497

8.

ADAR1 is essential for the maintenance of hematopoiesis and suppression of interferon signaling.

Hartner, Jochen C; Walkley, Carl R; Lu, Jun; Orkin, Stuart H.

Nat Immunol ; 10(1): 109-15, 2009 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-19060901

9.

Srsf2^P95H initiates myeloid bias and myelodysplastic/myeloproliferative syndrome from hemopoietic stem cells.

Smeets, Monique F; Tan, Shuh Ying; Xu, Jane Jialu; Anande, Govardhan; Unnikrishnan, Ashwin; Chalk, Alistair M; Taylor, Scott R; Pimanda, John E; Wall, Meaghan; Purton, Louise E; Walkley, Carl R.

Blood ; 132(6): 608-621, 2018 08 09.

Artigo em Inglês | MEDLINE | ID: mdl-29903888

10.

ADAR1-mediated RNA editing is required for thymic self-tolerance and inhibition of autoimmunity.

Nakahama, Taisuke; Kato, Yuki; Kim, Jung In; Vongpipatana, Tuangtong; Suzuki, Yutaka; Walkley, Carl R; Kawahara, Yukio.

EMBO Rep ; 19(12)2018 12.

Artigo em Inglês | MEDLINE | ID: mdl-30361393

11.

Defining the functions of adenosine-to-inosine RNA editing through hematology.

Heraud-Farlow, Jacki E; Chalk, Alistair M; Walkley, Carl R.

Curr Opin Hematol ; 26(4): 241-248, 2019 07.

Artigo em Inglês | MEDLINE | ID: mdl-31033705

12.

Patience is a virtue.

Walkley, Carl R.

Blood ; 139(4): 481-482, 2022 01 27.

Artigo em Inglês | MEDLINE | ID: mdl-35084474

13.

Ssb1 and Ssb2 cooperate to regulate mouse hematopoietic stem and progenitor cells by resolving replicative stress.

Shi, Wei; Vu, Therese; Boucher, Didier; Biernacka, Anna; Nde, Jules; Pandita, Raj K; Straube, Jasmin; Boyle, Glen M; Al-Ejeh, Fares; Nag, Purba; Jeffery, Jessie; Harris, Janelle L; Bain, Amanda L; Grzelak, Marta; Skrzypczak, Magdalena; Mitra, Abhishek; Dojer, Norbert; Crosetto, Nicola; Cloonan, Nicole; Becherel, Olivier J; Finnie, John; Skaar, Jeffrey R; Walkley, Carl R; Pandita, Tej K; Rowicka, Maga; Ginalski, Krzysztof; Lane, Steven W; Khanna, Kum Kum.

Blood ; 129(18): 2479-2492, 2017 05 04.

Artigo em Inglês | MEDLINE | ID: mdl-28270450

14.

Smac mimetics LCL161 and GDC-0152 inhibit osteosarcoma growth and metastasis in mice.

Shekhar, Tanmay M; Burvenich, Ingrid J G; Harris, Michael A; Rigopoulos, Angela; Zanker, Damien; Spurling, Alex; Parker, Belinda S; Walkley, Carl R; Scott, Andrew M; Hawkins, Christine J.

BMC Cancer ; 19(1): 924, 2019 Sep 14.

Artigo em Inglês | MEDLINE | ID: mdl-31521127

15.

Osteosarcoma in the Post Genome Era: Preclinical Models and Approaches to Identify Tractable Therapeutic Targets.

Castillo-Tandazo, Wilson; Mutsaers, Anthony J; Walkley, Carl R.

Curr Osteoporos Rep ; 17(5): 343-352, 2019 10.

Artigo em Inglês | MEDLINE | ID: mdl-31529263

16.

PDGF-AB and 5-Azacytidine induce conversion of somatic cells into tissue-regenerative multipotent stem cells.

Chandrakanthan, Vashe; Yeola, Avani; Kwan, Jair C; Oliver, Rema A; Qiao, Qiao; Kang, Young Chan; Zarzour, Peter; Beck, Dominik; Boelen, Lies; Unnikrishnan, Ashwin; Villanueva, Jeanette E; Nunez, Andrea C; Knezevic, Kathy; Palu, Cintia; Nasrallah, Rabab; Carnell, Michael; Macmillan, Alex; Whan, Renee; Yu, Yan; Hardy, Philip; Grey, Shane T; Gladbach, Amadeus; Delerue, Fabien; Ittner, Lars; Mobbs, Ralph; Walkley, Carl R; Purton, Louise E; Ward, Robyn L; Wong, Jason W H; Hesson, Luke B; Walsh, William; Pimanda, John E.

Proc Natl Acad Sci U S A ; 113(16): E2306-15, 2016 Apr 19.

Artigo em Inglês | MEDLINE | ID: mdl-27044077

17.

Murine models of osteosarcoma: A piece of the translational puzzle.

Walia, Mannu K; Castillo-Tandazo, Wilson; Mutsaers, Anthony J; Martin, Thomas John; Walkley, Carl R.

J Cell Biochem ; 119(6): 4241-4250, 2018 06.

Artigo em Inglês | MEDLINE | ID: mdl-29236321

18.

The DNA helicase recql4 is required for normal osteoblast expansion and osteosarcoma formation.

Ng, Alvin J M; Walia, Mannu K; Smeets, Monique F; Mutsaers, Anthony J; Sims, Natalie A; Purton, Louise E; Walsh, Nicole C; Martin, T John; Walkley, Carl R.

PLoS Genet ; 11(4): e1005160, 2015 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-25859855

19.

Brief report: the differential roles of mTORC1 and mTORC2 in mesenchymal stem cell differentiation.

Martin, Sally K; Fitter, Stephen; Dutta, Ankit K; Matthews, Mary P; Walkley, Carl R; Hall, Michael N; Ruegg, Markus A; Gronthos, Stan; Zannettino, Andrew C W.

Stem Cells ; 33(4): 1359-65, 2015 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-25537496

20.

Developmental and species-divergent globin switching are driven by BCL11A.

Sankaran, Vijay G; Xu, Jian; Ragoczy, Tobias; Ippolito, Gregory C; Walkley, Carl R; Maika, Shanna D; Fujiwara, Yuko; Ito, Masafumi; Groudine, Mark; Bender, M A; Tucker, Philip W; Orkin, Stuart H.

Nature ; 460(7259): 1093-7, 2009 Aug 27.

Artigo em Inglês | MEDLINE | ID: mdl-19657335

Portal de Pesquisa da BVS

Informação e Conhecimento para a Saúde

Configurar filtros

Sua seleção (0)

Formato de exportação:

Exportar: