Detalhe da pesquisa
1.
Breaking NGF-TrkA immunosuppression in melanoma sensitizes immunotherapy for durable memory T cell protection.
Nat Immunol
; 25(2): 268-281, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38195702
2.
Cancer-associated PTEN mutants act in a dominant-negative manner to suppress PTEN protein function.
Cell
; 157(3): 595-610, 2014 Apr 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-24766807
3.
Energy status dictates PD-L1 protein abundance and anti-tumor immunity to enable checkpoint blockade.
Mol Cell
; 81(11): 2317-2331.e6, 2021 06 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33909988
4.
Acetylation-dependent regulation of Skp2 function.
Cell
; 150(1): 179-93, 2012 Jul 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-22770219
5.
Phosphorylation of EZH2 by AMPK Suppresses PRC2 Methyltransferase Activity and Oncogenic Function.
Mol Cell
; 69(2): 279-291.e5, 2018 01 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-29351847
6.
An Epigenomic fingerprint of human cancers by landscape interrogation of super enhancers at the constituent level.
PLoS Comput Biol
; 20(2): e1011873, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38335222
7.
RAF-MEK-ERK pathway in cancer evolution and treatment.
Semin Cancer Biol
; 85: 123-154, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33992782
8.
ITCH as a potential therapeutic target in human cancers.
Semin Cancer Biol
; 67(Pt 2): 117-130, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32165318
9.
A covalently bound inhibitor triggers EZH2 degradation through CHIP-mediated ubiquitination.
EMBO J
; 36(9): 1243-1260, 2017 05 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28320739
10.
MC1R is a potent regulator of PTEN after UV exposure in melanocytes.
Mol Cell
; 51(4): 409-22, 2013 Aug 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-23973372
11.
Cell-cycle-regulated activation of Akt kinase by phosphorylation at its carboxyl terminus.
Nature
; 508(7497): 541-5, 2014 Apr 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-24670654
12.
Cdh1 regulates osteoblast function through an APC/C-independent modulation of Smurf1.
Mol Cell
; 44(5): 721-33, 2011 Dec 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-22152476
13.
mTOR drives its own activation via SCF(ßTrCP)-dependent degradation of the mTOR inhibitor DEPTOR.
Mol Cell
; 44(2): 290-303, 2011 Oct 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-22017875
14.
IRTKS is correlated with progression and survival time of patients with gastric cancer.
Gut
; 67(8): 1400-1409, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28647685
15.
Rictor forms a complex with Cullin-1 to promote SGK1 ubiquitination and destruction.
Mol Cell
; 39(5): 797-808, 2010 Sep 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-20832730
16.
Monoubiquitination Inhibits the Actin Bundling Activity of Fascin.
J Biol Chem
; 291(53): 27323-27333, 2016 12 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-27879315
17.
SCF(FBW7) regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction.
Nature
; 471(7336): 104-9, 2011 Mar 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-21368833
18.
Functional characterization of Anaphase Promoting Complex/Cyclosome (APC/C) E3 ubiquitin ligases in tumorigenesis.
Biochim Biophys Acta
; 1845(2): 277-93, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24569229
19.
Capecitabine or Capecitabine Plus Oxaliplatin Versus Fluorouracil Plus Cisplatin in Definitive Concurrent Chemoradiotherapy for Locally Advanced Esophageal Squamous Cell Carcinoma (CRTCOESC): A Multicenter, Randomized, Open-Label, Phase 3 Trial.
J Clin Oncol
; : JCO2302009, 2024 May 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38710003
20.
Skp2: a novel potential therapeutic target for prostate cancer.
Biochim Biophys Acta
; 1825(1): 11-7, 2012 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-21963805