Detalhe da pesquisa
1.
Pharmacogenomics: Driving Personalized Medicine.
Pharmacol Rev
; 75(4): 789-814, 2023 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-36927888
2.
A Comprehensive Evaluation of the Effects of RNA-Editing Proteins ADAR and ADARB1 on the Expression of the Drug-Metabolizing Enzymes in HepaRG Cells.
Drug Metab Dispos
; 51(11): 1508-1514, 2023 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37532539
3.
Regulation of CYP3A4 and CYP3A5 by a lncRNA: a potential underlying mechanism explaining the association between CYP3A4*1G and CYP3A metabolism.
Pharmacogenet Genomics
; 32(1): 16-23, 2022 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34320606
4.
Transcriptional Regulation of Carboxylesterase 1 in Human Liver: Role of the Nuclear Receptor Subfamily 1 Group H Member 3 and Its Splice Isoforms.
Drug Metab Dispos
; 50(1): 43-48, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34697082
5.
Association Between Social Determinants of Health and Glycemic Control Among African American People with Type 2 diabetes: The Jackson Heart Study.
Ann Behav Med
; 56(12): 1300-1311, 2022 11 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-36197118
6.
Functional CYP3A variants affecting tacrolimus trough blood concentrations in Chinese renal transplant recipients.
Pharmacogenomics J
; 21(3): 376-389, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33649515
7.
ESR1 ChIP-Seq Identifies Distinct Ligand-Free ESR1 Genomic Binding Sites in Human Hepatocytes and Liver Tissue.
Int J Mol Sci
; 22(3)2021 Feb 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33540646
8.
Cis-acting regulatory elements regulating CYP3A4 transcription in human liver.
Pharmacogenet Genomics
; 30(5): 107-116, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32301865
9.
Response to the Comments on "Determining Allele-Specific Protein Expression (ASPE) Using a Novel Quantitative Concatamer Proteomics Method".
J Proteome Res
; 18(3): 1458-1459, 2019 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30616350
10.
Ligand-Free Estrogen Receptor α (ESR1) as Master Regulator for the Expression of CYP3A4 and Other Cytochrome P450 Enzymes in the Human Liver.
Mol Pharmacol
; 96(4): 430-440, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31399483
11.
CYP2D6 haplotypes with enhancer single-nucleotide polymorphism rs5758550 and rs16947 (*2 allele): implications for CYP2D6 genotyping panels.
Pharmacogenet Genomics
; 29(2): 39-47, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30520769
12.
XRCC1-mediated DNA repair is associated with progression-free survival of multiple myeloma patients after autologous stem cell transplant.
Mol Carcinog
; 58(12): 2327-2339, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31544312
13.
Association of Regulatory Genetic Variants for Protein Kinase Cα with Mortality and Drug Efficacy in Patients with Heart Failure.
Cardiovasc Drugs Ther
; 33(6): 693-700, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31728800
14.
Determining Allele-Specific Protein Expression (ASPE) Using a Novel Quantitative Concatamer Based Proteomics Method.
J Proteome Res
; 17(10): 3606-3612, 2018 10 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30141943
15.
Multimodal Rehabilitation Program Promotes Motor Function Recovery of Rats After Ischemic Stroke by Upregulating Expressions of GAP-43, SYN, HSP70, and C-MYC.
J Stroke Cerebrovasc Dis
; 27(10): 2829-2839, 2018 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-30093210
16.
The CHRNA5/CHRNA3/CHRNB4 Nicotinic Receptor Regulome: Genomic Architecture, Regulatory Variants, and Clinical Associations.
Hum Mutat
; 38(1): 112-119, 2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27758088
17.
Functional characterization of CYP2D6 enhancer polymorphisms.
Hum Mol Genet
; 24(6): 1556-62, 2015 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25381333
18.
Regulatory Variants Modulate Protein Kinase C α (PRKCA) Gene Expression in Human Heart.
Pharm Res
; 34(8): 1648-1657, 2017 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-28120175
19.
Common CYP2D6 polymorphisms affecting alternative splicing and transcription: long-range haplotypes with two regulatory variants modulate CYP2D6 activity.
Hum Mol Genet
; 23(1): 268-78, 2014 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23985325
20.
Quantifying rare, deleterious variation in 12 human cytochrome P450 drug-metabolism genes in a large-scale exome dataset.
Hum Mol Genet
; 23(8): 1957-63, 2014 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24282029