Detalhe da pesquisa
1.
2,2- dimethylbenzopyran derivatives containing pyridone structural fragments as selective dual-targeting inhibitors of HIF-1α and EZH2 for the treatment of lung cancer.
Bioorg Chem
; 147: 107419, 2024 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-38703440
2.
Structure of the Major G-Quadruplex in the Human EGFR Oncogene Promoter Adopts a Unique Folding Topology with a Distinctive Snap-Back Loop.
J Am Chem Soc
; 145(29): 16228-16237, 2023 07 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-37460135
3.
Oxidative Damage Induces a Vacancy G-Quadruplex That Binds Guanine Metabolites: Solution Structure of a cGMP Fill-in Vacancy G-Quadruplex in the Oxidized BLM Gene Promoter.
J Am Chem Soc
; 144(14): 6361-6372, 2022 04 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-35352895
4.
(±)-Pheharmines A-B, two pairs of racemic alkaloids with a morpholino[4,3,2-hi]ß-carboline core, from the roots of Peganum harmala.
Org Biomol Chem
; 20(43): 8528-8532, 2022 Nov 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36278495
5.
Effects of vegetation restoration types on soil nutrients and soil erodibility regulated by slope positions on the Loess Plateau.
J Environ Manage
; 302(Pt A): 113985, 2022 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34700089
6.
Solution Structure of Ternary Complex of Berberine Bound to a dGMP-Fill-In Vacancy G-Quadruplex Formed in the PDGFR-ß Promoter.
J Am Chem Soc
; 143(40): 16549-16555, 2021 10 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-34586799
7.
Evaluating Molecular Docking Software for Small Molecule Binding to G-Quadruplex DNA.
Int J Mol Sci
; 22(19)2021 Oct 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34639142
8.
PDGFR-ß Promoter Forms a Vacancy G-Quadruplex that Can Be Filled in by dGMP: Solution Structure and Molecular Recognition of Guanine Metabolites and Drugs.
J Am Chem Soc
; 142(11): 5204-5211, 2020 03 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-32101424
9.
Soil GHG fluxes are altered by N deposition: New data indicate lower N stimulation of the N2 O flux and greater stimulation of the calculated C pools.
Glob Chang Biol
; 26(4): 2613-2629, 2020 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-31863618
10.
Norcolocynthenins A and B, two cucurbitane 3-nor-Triterpenoids from Citrullus colocynthis and their cytotoxicity.
Bioorg Chem
; 101: 104045, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32629288
11.
Indenoisoquinoline Topoisomerase Inhibitors Strongly Bind and Stabilize the MYC Promoter G-Quadruplex and Downregulate MYC.
J Am Chem Soc
; 141(28): 11059-11070, 2019 07 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-31283877
12.
Production of plant-specific flavones baicalein and scutellarein in an engineered E. coli from available phenylalanine and tyrosine.
Metab Eng
; 52: 124-133, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30496827
13.
Ligand Selectivity in the Recognition of Protoberberine Alkaloids by Hybrid-2 Human Telomeric G-Quadruplex: Binding Free Energy Calculation, Fluorescence Binding, and NMR Experiments.
Molecules
; 24(8)2019 Apr 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31010072
14.
Cytotoxic quinazoline alkaloids from the seeds of Peganum harmala.
Bioorg Med Chem Lett
; 28(2): 103-106, 2018 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29229205
15.
Molecular Recognition of the Hybrid-2 Human Telomeric G-Quadruplex by Epiberberine: Insights into Conversion of Telomeric G-Quadruplex Structures.
Angew Chem Int Ed Engl
; 57(34): 10888-10893, 2018 08 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-29888501
16.
Neobraclactones A-C, three unprecedented chaise longue-shaped xanthones from Garcinia bracteata.
Org Biomol Chem
; 15(22): 4901-4906, 2017 Jun 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28541369
17.
Antiproliferative Dimeric Aporphinoid Alkaloids from the Roots of Thalictrum cultratum.
J Nat Prod
; 80(11): 2893-2904, 2017 11 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-29131616
18.
Structurally Diverse Alkaloids from the Seeds of Peganum harmala.
J Nat Prod
; 80(2): 551-559, 2017 02 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-28128938
19.
Preparative Isolation of Two Prenylated Biflavonoids from the Roots and Rhizomes of Sinopodophyllum emodi by Sephadex LH-20 Column and High-Speed Counter-Current Chromatography.
Molecules
; 21(1): E10, 2015 Dec 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-26703555
20.
The discovery of an anti-Candida xanthone with selective inhibition of Candida albicans GAPDH.
Int J Antimicrob Agents
; 63(6): 107172, 2024 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-38608845