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1.
Zhongguo Yi Liao Qi Xie Za Zhi ; 40(2): 137-9, 2016 Mar.
Artigo em Chinês | MEDLINE | ID: mdl-29763234

RESUMO

First, simply expounded the purpose and meaning of detecting tungsten extracted from prefi lable syringes: And then, designed simulation experiment for extracting tungsten from prefi lable glass syringes. and established determination methods of tungsten content by ICP-MSL Finaly, evaluated the limit of content of tungsten ?extracting from simulation experiment.


Assuntos
Seringas , Tungstênio
2.
J Biomed Inform ; 57: 20-7, 2015 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-26146158

RESUMO

Based on the latest statistics on trends in cancer incidence and mortality worldwide, cancer burden is growing at an alarming pace. Many anticancer drugs have been proved effective against cancer cells as well as toxic to human tissues, which prevents sufficient doses from being administered to obtain a complete cure. In this paper we build an optimal control model to optimize the scheduling problem along one cycle of chemotherapy treatment using a single anticancer drug etoposide (VP-16). In the model, three mathematic models are adopted to mimic physiological response of body under chemotherapy: (i) Pharmacokinetic model of anticancer drug; (ii) A two-compartment tumor growth dynamic model under the influence of cell-cycle-specific anticancer drugs; and (iii) A semi-mechanistic model for myelosuppression. In this new integrated model clinically relevant objectives are proposed to gain a trade-off between efficacy and toxicity. Simulation results of clinical protocols are consistent with real-life clinical data. Furthermore, we find a new optimal drug regimen which can improve the efficacy without the risk of severe toxicity.


Assuntos
Antineoplásicos/efeitos adversos , Modelos Teóricos , Neutropenia/induzido quimicamente , Antineoplásicos/uso terapêutico , Etoposídeo/efeitos adversos , Etoposídeo/uso terapêutico , Humanos , Neoplasias/tratamento farmacológico
3.
Zhongguo Yi Liao Qi Xie Za Zhi ; 38(5): 371-4, 2014 Sep.
Artigo em Chinês | MEDLINE | ID: mdl-25597089

RESUMO

This paper discussed the building of post market risk analysis method in hemodialysis device from the point of government supervision. By proposing practical research methods for post market risk identification and estimation on hemodialysis device, providing technical guidance for government to put risk management of hemodialysis device into effect, and offering reference for enterprises to carry out post market risk evaluation on their products as well.


Assuntos
Diálise Renal/instrumentação , Diálise Renal/normas , Medição de Risco , Regulamentação Governamental , Projetos de Pesquisa , Gestão de Riscos
4.
Zhongguo Yi Liao Qi Xie Za Zhi ; 35(2): 131-3, 2011 Mar.
Artigo em Chinês | MEDLINE | ID: mdl-21706800

RESUMO

Through the analysis of the current drug testing market, this paper discussion the meeting of creating "Drug Testing in China" brand on the concept of scientific testing.


Assuntos
Indústria Farmacêutica/organização & administração , Assistência Farmacêutica/organização & administração , China , Preparações Farmacêuticas , Controle de Qualidade
5.
Zhongguo Yi Liao Qi Xie Za Zhi ; 31(5): 367-70, 2007 Sep.
Artigo em Chinês | MEDLINE | ID: mdl-18161379

RESUMO

This paper introduces the temperature rising experimental process and some matters needing attention when the transformer is normally loading. And an analysis of the uncertainty for transformer's temperature rising is also made based on the practical examples' data.


Assuntos
Eletricidade , Temperatura , Segurança de Equipamentos , Incerteza
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