Detalhe da pesquisa
1.
MyosinA is a druggable target in the widespread protozoan parasite Toxoplasma gondii.
PLoS Biol
; 21(5): e3002110, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37155705
2.
Structural and mechanistic insights into the function of the unconventional class XIV myosin MyoA from Toxoplasma gondii.
Proc Natl Acad Sci U S A
; 115(45): E10548-E10555, 2018 11 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30348763
3.
Dissecting the molecular assembly of the Toxoplasma gondii MyoA motility complex.
J Biol Chem
; 292(47): 19469-19477, 2017 11 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-28972141
4.
Surface attachment, promoted by the actomyosin system of Toxoplasma gondii is important for efficient gliding motility and invasion.
BMC Biol
; 15(1): 1, 2017 01 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-28100223
5.
A Toxoplasma gondii class XIV myosin, expressed in Sf9 cells with a parasite co-chaperone, requires two light chains for fast motility.
J Biol Chem
; 289(44): 30832-30841, 2014 Oct 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-25231988
6.
Intramembrane proteolysis of Toxoplasma apical membrane antigen 1 facilitates host-cell invasion but is dispensable for replication.
Proc Natl Acad Sci U S A
; 109(19): 7463-8, 2012 May 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-22523242
7.
Identification of Cryptosporidium parvum active chemical series by Repurposing the open access malaria box.
Antimicrob Agents Chemother
; 58(5): 2731-9, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24566188
8.
Chemical genetic screen identifies Toxoplasma DJ-1 as a regulator of parasite secretion, attachment, and invasion.
Proc Natl Acad Sci U S A
; 108(26): 10568-73, 2011 Jun 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-21670272
9.
A modular approach to triazole-containing chemical inducers of dimerisation for yeast three-hybrid screening.
Molecules
; 18(9): 11639-57, 2013 Sep 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-24064457
10.
The Toxoplasma subpellicular network is highly interconnected and defines parasite shape for efficient motility and replication.
bioRxiv
; 2023 Aug 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37609316
11.
CDPK2A and CDPK1 form a signaling module upstream of Toxoplasma motility.
mBio
; 14(5): e0135823, 2023 Oct 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-37610220
12.
A small-molecule inhibitor of T. gondii motility induces the posttranslational modification of myosin light chain-1 and inhibits myosin motor activity.
PLoS Pathog
; 6(1): e1000720, 2010 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20084115
13.
A circular zone of attachment to the extracellular matrix provides directionality to the motility of Toxoplasma gondii in 3D.
Elife
; 112022 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36519527
14.
Toxoplasma gondii transmembrane microneme proteins and their modular design.
Mol Microbiol
; 77(4): 912-29, 2010 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-20545864
15.
Blocking Palmitoylation of Toxoplasma gondii Myosin Light Chain 1 Disrupts Glideosome Composition but Has Little Impact on Parasite Motility.
mSphere
; 6(3)2021 05 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-34011689
16.
Gene expression signatures and small-molecule compounds link a protein kinase to Plasmodium falciparum motility.
Nat Chem Biol
; 4(6): 347-56, 2008 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-18454143
17.
GAP45 phosphorylation controls assembly of the Toxoplasma myosin XIV complex.
Eukaryot Cell
; 8(2): 190-6, 2009 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-19047362
18.
IDENTIFICATION OF CONOIDIN A AS A COVALENT INHIBITOR OF PEROXIREDOXIN II.
Org Biomol Chem
; 7: 3040-3048, 2009.
Artigo
em Inglês
| MEDLINE | ID: mdl-21359112
19.
Current and emerging approaches to studying invasion in apicomplexan parasites.
Subcell Biochem
; 47: 1-32, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-18512338
20.
Differential requirements for cyclase-associated protein (CAP) in actin-dependent processes of Toxoplasma gondii.
Elife
; 82019 10 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31577230