Detalhe da pesquisa
1.
Wolbachia depletion blocks transmission of lymphatic filariasis by preventing chitinase-dependent parasite exsheathment.
Proc Natl Acad Sci U S A
; 119(15): e2120003119, 2022 04 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35377795
2.
AWZ1066S, a highly specific anti-Wolbachia drug candidate for a short-course treatment of filariasis.
Proc Natl Acad Sci U S A
; 116(4): 1414-1419, 2019 01 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-30617067
3.
M1 macrophage features in severe Plasmodium falciparum malaria patients with pulmonary oedema.
Malar J
; 19(1): 182, 2020 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32414377
4.
Albendazole and antibiotics synergize to deliver short-course anti-Wolbachia curative treatments in preclinical models of filariasis.
Proc Natl Acad Sci U S A
; 114(45): E9712-E9721, 2017 11 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29078351
5.
Human Direct Skin Feeding Versus Membrane Feeding to Assess the Mosquitocidal Efficacy of High-Dose Ivermectin (IVERMAL Trial).
Clin Infect Dis
; 69(7): 1112-1119, 2019 09 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-30590537
6.
Intracellular Pharmacodynamic Modeling Is Predictive of the Clinical Activity of Fluoroquinolones against Tuberculosis.
Antimicrob Agents Chemother
; 64(1)2019 12 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-31611354
7.
Intra-individual effects of food upon the pharmacokinetics of rifampicin and isoniazid.
J Antimicrob Chemother
; 74(2): 416-424, 2019 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30412245
8.
Artemisinin activity-based probes identify multiple molecular targets within the asexual stage of the malaria parasites Plasmodium falciparum 3D7.
Proc Natl Acad Sci U S A
; 113(8): 2080-5, 2016 Feb 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-26858419
9.
Synthesis and profiling of benzylmorpholine 1,2,4,5-tetraoxane analogue N205: Towards tetraoxane scaffolds with potential for single dose cure of malaria.
Bioorg Med Chem
; 26(11): 2996-3005, 2018 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29779669
10.
Antimalarial 4(1H)-pyridones bind to the Qi site of cytochrome bc1.
Proc Natl Acad Sci U S A
; 112(3): 755-60, 2015 Jan 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-25564664
11.
OptiMal-PK: an internet-based, user-friendly interface for the mathematical-based design of optimized anti-malarial treatment regimens.
Malar J
; 15(1): 344, 2016 07 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27388207
12.
PFMDR1 POLYMORPHISMS INFLUENCE ON IN VITRO SENSITIVITY OF THAI PLASMODIUM FALCIPARUM ISOLATES TO PRIMAQUINE, SITAMAQUINE AND TAFENOQUINE.
Southeast Asian J Trop Med Public Health
; 47(3): 366-76, 2016 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-27405118
13.
A Click Chemistry-Based Proteomic Approach Reveals that 1,2,4-Trioxolane and Artemisinin Antimalarials Share a Common Protein Alkylation Profile.
Angew Chem Int Ed Engl
; 55(22): 6401-5, 2016 05 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-27089538
14.
Baseline data of parasite clearance in patients with falciparum malaria treated with an artemisinin derivative: an individual patient data meta-analysis.
Malar J
; 14: 359, 2015 Sep 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-26390866
15.
Generation of quinolone antimalarials targeting the Plasmodium falciparum mitochondrial respiratory chain for the treatment and prophylaxis of malaria.
Proc Natl Acad Sci U S A
; 109(21): 8298-303, 2012 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-22566611
16.
Effects of dosage, comorbidities, and food on isoniazid pharmacokinetics in Peruvian tuberculosis patients.
Antimicrob Agents Chemother
; 58(12): 7164-70, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25224007
17.
Rapid kill of malaria parasites by artemisinin and semi-synthetic endoperoxides involves ROS-dependent depolarization of the membrane potential.
J Antimicrob Chemother
; 69(4): 1005-16, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24335485
18.
Pharmacokinetics of co-formulated mefloquine and artesunate in pregnant and non-pregnant women with uncomplicated Plasmodium falciparum infection in Burkina Faso.
J Antimicrob Chemother
; 69(9): 2499-507, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-24891429
19.
Anti-Wolbachia drug discovery and development: safe macrofilaricides for onchocerciasis and lymphatic filariasis.
Parasitology
; 141(1): 119-27, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23866958
20.
Metabolite footprinting of Plasmodium falciparum following exposure to Garcinia mangostana Linn. crude extract.
Exp Parasitol
; 145: 80-6, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25102435