RESUMO
Adenoid cystic carcinoma of the breast is a rare tumor having a favorable prognosis. At this writing, less than 100 cases have been reported. A review of the literature discloses only six well-documented cases with associated distant metastases. The characteristic biological behavior of this tumor appears to be the development of distant metastasis without prior detectable invasion of axillary lymph nodes.
Assuntos
Neoplasias da Mama/patologia , Carcinoma Adenoide Cístico/patologia , Feminino , Humanos , Pessoa de Meia-Idade , Metástase NeoplásicaRESUMO
Two separate primary carcinomas occurring simultaneously in the esophagus and stomach are uncommon. The authors report three cases of this entity, squamous cell carcinoma of the osophagus and adenocarcinoma of the stomach, one of which is classified as a collision carcinoma of the stomach. Because of the rarity of collision tumors of this histologic variety, the world literature was reviewed. Diagnostic features and the relative prognosis of dual primary carcinomas are discussed.
Assuntos
Adenocarcinoma/diagnóstico , Carcinoma de Células Escamosas/diagnóstico , Neoplasias Esofágicas/diagnóstico , Neoplasias Primárias Múltiplas/diagnóstico , Neoplasias Gástricas/diagnóstico , Idoso , Humanos , Masculino , Pessoa de Meia-Idade , PrognósticoRESUMO
A case is presented of tricuspid valve and papillary muscle avulsion which occurred during removal of a Swan-Ganz catheter. A review of pertinent literature and discussion of a possible mechanism for the cause of the complication and its prevention are presented.The authors believe this to be the first reported instance of such a complication.
Assuntos
Cateterismo/efeitos adversos , Músculos Papilares/lesões , Valva Tricúspide/lesões , Idoso , Humanos , MasculinoRESUMO
Loss of integrity of the thoracic duct will produce a chylous thoracic effusion. latrogenic chylothorax occurring during an intrathoracic surgical procedure in the vicinity of the thoracic duct is an omnipresent reality. The fluid is characteristically milky in appearance, sterile, and high in fat content.There seems to be a general agreement that initial management be conservative, namely, dietary control and adequate drainage. The success of conservative management will depend on collateral lymphatic channels developing. If conservative measures fail, thoracotomy for ligation of the duct is indicated. When to terminate nonoperative therapy and opt for operative is controversial.
Assuntos
Carcinoma de Células Escamosas/cirurgia , Quilotórax/cirurgia , Neoplasias Esofágicas/cirurgia , Complicações Pós-Operatórias/cirurgia , Feminino , Humanos , Doença Iatrogênica , Pessoa de Meia-Idade , Ducto Torácico/lesõesRESUMO
Eighty-three cases of tracheopleuropulmonary injuries complicating enteral tube feeding are analyzed to identify the patterns of injury, and precipitating factors and ways to avoid them. Six new cases observed by the authors and 77 other cases cited in British literature between 1976 and 1987 are presented. In recent years, reports of this complication have been increasing, apparently in a geometrical progression: 8%, 18%, and 74% were reported between 1976 to 1979, 1980 to 1983, and 1984 to 1987, respectively. Sixty-one percent occurred in patients aged 60 years or older. Most of the patients (84%) were seriously ill, which compounded their complications. Seventy-four percent of all injuries were committed by house staff; the narrow bore tube with guide wire was used in 77% of cases. Less than reliable methods were used to confirm tube position in most instances. The presence of cuffed endotracheal tubes did not offer protection. The patients on mechanical ventilation tended to deteriorate if they developed a pneumothorax once the malpositioned tubes were removed. Of the cases reviewed for this report, 18 deaths occurred; 72% being directly related to the tube injuries. Lack of awareness, inadequate confirmatory methods, and insufficient supervision accounted for most of these preventable complications. Educating house/nursing staff in the use of the new tubes, closer supervision, and the application of equal measures of care and caution as employed in other invasive and potentially dangerous procedures are recommended to avoid disastrous outcome.
Assuntos
Nutrição Enteral/efeitos adversos , Lesão Pulmonar , Pleura/lesões , Traqueia/lesões , Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Masculino , Pessoa de Meia-IdadeRESUMO
The diagnosis of sarcoidosis, as with other intrathoracic lesions, remains a challenge to the clinician. An adequate history, a thorough physical examination, and the employment of various laboratory tests often establish the diagnosis. When a definitive diagnosis is not made, biopsy of suspected lesions is indicated. Various diagnostic procedures are presented and compared.
Assuntos
Sarcoidose/diagnóstico , Adolescente , Adulto , Biópsia , Técnicas de Laboratório Clínico , Humanos , Pulmão/patologia , Mediastinoscopia , Radiografia , Sarcoidose/diagnóstico por imagemRESUMO
The objective of radiotherapeutic management in esophageal cancer is to accomplish maximum tumor sterilization with minimal normal tissue damage. This sincere effort is most often countered by the differential in tumor dose response vs normal tissue tolerance. Intraluminal isotope radiation, with its inherent advantage of rapid dose falloff, spares the lungs, the spinal cord, and other vital structures, yet yields adequately high doses to esophageal tumor. Though in existence since the turn of the century, the method of intracavitary radium bougie application dropped out of favor due to technical difficulties imposed by the size of the radium source and radiation exposure to the personnel involved. The authors describe a simple "iridium 192 afterloading intraluminal technique" that eliminates technical problems and reduces radiation exposure considerably.
Assuntos
Braquiterapia/métodos , Neoplasias Esofágicas/radioterapia , HumanosRESUMO
The preoperative profiles of a predominately non-white group of patients undergoing coronary artery bypass grafting were reviewed. Data were obtained from a retrospective analysis of medical records of 163 patients operated on at Howard University Hospital between July 1983 and July 1986. The analysis was carried out primarily to determine whether patients requiring myocardial revascularization were somehow different from their non-black counterparts. Ninety-one percent of the patients were black, 5 percent white, 0.5 percent Hispanic, and 3.5 percent others (Iranian, Filipino, etc).The study was not designed to review the prevalence of coronary disease in blacks, or to determine the natural history following coronary artery bypass grafting, but to determine whether those with established coronary disease of such a severity as to warrant revascularization had the usual clustering of risk factors. Patient records were reviewed to determine the prevalence of hypertension, diabetes, obesity, cigarette smoking, previous myocardial injury, and total serum cholesterol. Because of the well-recognized increased incidence of hypertension in black patients, and its role as a major risk factor in coronary heart disease, the sequelae of hypertension were considered in relation to results of surgical therapy.The study population included 93 men (57 percent) and 70 women (43 percent); mean age was 59 years (fourth to ninth decade). Seventy-four percent of the patients were hypertensive, 35 percent were diabetic, and 77 percent had a smoking history. Obesity was prevalent among the female patients in general, with 36 percent of the diabetics and 21 percent of the nondiabetics being greater than 50 percent over ideal body weight. Ninety percent of the female patients and 80 percent of the male patients presented with New York Heart Association class III or IV angina. Left ventricular function was, on the average, well preserved. The immediate surgical mortality (following exclusion of patients in extremis) was 4 percent. The surgical mortalities were related to easily identifiable factors. Peri-operative infarctions were profoundly influenced by the presence of diabetes.Although this group was distinguished from most reported groups of patients undergoing aortocoronary bypass grafting by the presence of advanced age, the large percentage of women and diabetics and the marked prevalence of hypertension, and the usual risk factors for coronary artery disease reported in the majority population, the study reconfirms previous epidemiologic findings. It appears that racial "clumping" of a heterogeneous non-white population has minimal usefulness, except as it may be related to socioeconomic status and access to quality health care.
Assuntos
População Negra , Ponte de Artéria Coronária , Adulto , Idoso , District of Columbia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , RiscoAssuntos
Pneumotórax/diagnóstico por imagem , Adulto , Fatores Etários , Diagnóstico Diferencial , Feminino , Humanos , Menstruação , Gravidez , Radiografia , RecidivaRESUMO
A case is reported of a successful transplant of kidneys from a 15-month-old girl who died of complications of Reye's syndrome. The patient is well 28 months after the transplant and, despite treatment for 2 rejection episodes, there had been no increase in viral serologic titers nor evidence of the clinical viral syndrome. The literature on renal transplantation in Reye's syndrome as well as Reye's syndrome itself is reviewed. The world literature on this subject is sparse and this case is presented to give support and justification for the use of Reye's syndrome cadaver donors.