Detalhe da pesquisa
1.
Synthesis and biological activity of 5',9-anhydro-3-purine-isonucleosides as potential anti-hepatitis C virus agents.
Nucleosides Nucleotides Nucleic Acids
; 26(1): 83-97, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-17162589
2.
Synthesis and structure-activity relationships of novel anti-hepatitis C agents: N3,5'-cyclo-4-(beta-D-ribofuranosyl)-vic-triazolo[4,5-b]pyridin-5-one derivatives.
J Med Chem
; 48(20): 6454-60, 2005 Oct 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-16190771
3.
Design, synthesis, and antiviral activity of 2'-deoxy-2'-fluoro-2'-C-methylcytidine, a potent inhibitor of hepatitis C virus replication.
J Med Chem
; 48(17): 5504-8, 2005 Aug 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-16107149
4.
Unusual olefin formation by PhSe-F trans-elimination.
Nucleosides Nucleotides Nucleic Acids
; 24(9): 1289-92, 2005.
Artigo
em Inglês
| MEDLINE | ID: mdl-16252665
5.
Synthesis and anti-hepatitis C virus activity of nucleoside derivatives of N3, 5'-anhydro-4-(beta-D-ribofuranosyl)-8-aza-purin-2-ones.
Nucleosides Nucleotides Nucleic Acids
; 24(5-7): 961-4, 2005.
Artigo
em Inglês
| MEDLINE | ID: mdl-16248072
6.
N4-hydroxycytosine dioxolane nucleosides and their activity against hepatitis B virus.
Nucleosides Nucleotides Nucleic Acids
; 24(8): 1209-14, 2005.
Artigo
em Inglês
| MEDLINE | ID: mdl-16270663
7.
Synthesis and anti-HCV activity of N9,5'-cyclo-3-(beta-D-ribofuranosyl)-8-azapurin-2-one derivatives.
Nucleosides Nucleotides Nucleic Acids
; 24(10-12): 1531-42, 2005.
Artigo
em Inglês
| MEDLINE | ID: mdl-16438033
8.
Synthesis of N3,5'-cyclo-4-(beta-D-ribofuranosyl)-vic-triazolo[4,5-b]pyridin-5-one and its 3'-deoxysugar analogue as potential anti-hepatitis C virus agents.
Nucleosides Nucleotides Nucleic Acids
; 24(5-7): 957-60, 2005.
Artigo
em Inglês
| MEDLINE | ID: mdl-16248071
9.
Synthesis and in vitro anti-HCV activity of beta-D- and 1-2'-deoxy-2'-fluororibonucleosides.
Nucleosides Nucleotides Nucleic Acids
; 24(5-7): 875-9, 2005.
Artigo
em Inglês
| MEDLINE | ID: mdl-16248053
10.
The chemistry of nicotinamide adenine dinucleotide (NAD) analogues containing C-nucleosides related to nicotinamide riboside.
Curr Med Chem
; 9(7): 733-41, 2002 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-11966436
11.
Novel mycophenolic adenine bis(phosphonate) analogues as potential differentiation agents against human leukemia.
J Med Chem
; 45(3): 703-12, 2002 Jan 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-11806722
12.
Synthesis of N3,5'-cyclo-4-(beta-D-ribofuranosyl)-vic-triazolo[4,5-b]pyridin-5-one, a novel compound with anti-hepatitis C virus activity.
J Med Chem
; 47(24): 6100-3, 2004 Nov 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-15537363
13.
Inhibitors of the IMPDH enzyme as potential anti-bovine viral diarrhoea virus agents.
Antivir Chem Chemother
; 13(6): 345-52, 2002 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-12718406
14.
N4-acyl-modified D-2',3'-dideoxy-5-fluorocytidine nucleoside analogues with improved antiviral activity.
Antivir Chem Chemother
; 14(2): 81-90, 2003 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-12856919
15.
Synthesis and antiviral evaluation of 2',3'-dideoxy-2'-fluoro-3'- C-hydroxymethyl-beta-D-arabinofuranosyl pyrimidine nucleosides.
Nucleosides Nucleotides Nucleic Acids
; 22(5-8): 891-4, 2003.
Artigo
em Inglês
| MEDLINE | ID: mdl-14565304
16.
Synthesis and antiviral activity of 2'-deoxy-2'-fluoro-2'-C-methyl purine nucleosides as inhibitors of hepatitis C virus RNA replication.
Bioorg Med Chem Lett
; 16(6): 1712-5, 2006 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16368235
17.
Synthesis and anti-viral activity of a series of d- and l-2'-deoxy-2'-fluororibonucleosides in the subgenomic HCV replicon system.
Bioorg Med Chem
; 13(5): 1641-52, 2005 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15698782
18.
Synthesis of 5'-C-methyl-1',3'-dioxolan-4'-yl nucleosides.
Bioorg Med Chem Lett
; 14(5): 1243-5, 2004 Mar 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-14980674
19.
Inhibition of the subgenomic hepatitis C virus replicon in huh-7 cells by 2'-deoxy-2'-fluorocytidine.
Antimicrob Agents Chemother
; 48(2): 651-4, 2004 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-14742230
20.
Imidazoleacetic acid-ribotide: an endogenous ligand that stimulates imidazol(in)e receptors.
Proc Natl Acad Sci U S A
; 101(37): 13677-82, 2004 Sep 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-15365189