Detalhe da pesquisa
1.
A RhoA-YAP-c-Myc signaling axis promotes the development of polycystic kidney disease.
Genes Dev
; 32(11-12): 781-793, 2018 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29891559
2.
Monoallelic IFT140 pathogenic variants are an important cause of the autosomal dominant polycystic kidney-spectrum phenotype.
Am J Hum Genet
; 109(1): 136-156, 2022 01 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34890546
3.
Sex, Genotype, and Liver Volume Progression as Risk of Hospitalization Determinants in Autosomal Dominant Polycystic Liver Disease.
Gastroenterology
; 166(5): 902-914, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38101549
4.
Polycystin-2-dependent transcriptome reveals early response of autosomal dominant polycystic kidney disease.
Physiol Genomics
; 55(11): 565-577, 2023 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37720991
5.
A genetic screen in Drosophila reveals an unexpected role for the KIP1 ubiquitination-promoting complex in male fertility.
PLoS Genet
; 16(12): e1009217, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33378371
6.
GDNF drives rapid tubule morphogenesis in a novel 3D in vitro model for ADPKD.
J Cell Sci
; 133(14)2020 07 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-32513820
7.
Polycystin-1 dependent regulation of polycystin-2 via GRP94, a member of HSP90 family that resides in the endoplasmic reticulum.
FASEB J
; 35(10): e21865, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34486178
8.
A disease progression model estimating the benefit of tolvaptan on time to end-stage renal disease for patients with rapidly progressing autosomal dominant polycystic kidney disease.
BMC Nephrol
; 23(1): 334, 2022 10 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-36258169
9.
TWEAK Signaling Pathway Blockade Slows Cyst Growth and Disease Progression in Autosomal Dominant Polycystic Kidney Disease.
J Am Soc Nephrol
; 32(8): 1913-1932, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34155062
10.
Primary results of the randomized trial of metformin administration in polycystic kidney disease (TAME PKD).
Kidney Int
; 100(3): 684-696, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34186056
11.
The mitochondrial transporter SLC25A25 links ciliary TRPP2 signaling and cellular metabolism.
PLoS Biol
; 16(8): e2005651, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30080851
12.
Mutations in GANAB, Encoding the Glucosidase IIα Subunit, Cause Autosomal-Dominant Polycystic Kidney and Liver Disease.
Am J Hum Genet
; 98(6): 1193-1207, 2016 06 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27259053
13.
Left ventricular hypertrophy in a contemporary cohort of autosomal dominant polycystic kidney disease patients.
BMC Nephrol
; 20(1): 386, 2019 10 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-31653199
14.
Cardiac function assessed by myocardial deformation in adult polycystic kidney disease patients.
BMC Nephrol
; 20(1): 324, 2019 08 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-31419965
15.
A Practical Guide for Treatment of Rapidly Progressive ADPKD with Tolvaptan.
J Am Soc Nephrol
; 29(10): 2458-2470, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30228150
16.
A novel ARPKD mouse model with near-complete deletion of the Polycystic Kidney and Hepatic Disease 1 (Pkhd1) genomic locus presents with multiple phenotypes but not renal cysts.
Kidney Int
; 104(3): 611-616, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37419448
17.
A Randomized Clinical Trial of Metformin to Treat Autosomal Dominant Polycystic Kidney Disease.
Am J Nephrol
; 47(5): 352-360, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29779024
18.
A novel model of autosomal recessive polycystic kidney questions the role of the fibrocystin C-terminus in disease mechanism.
Kidney Int
; 92(5): 1130-1144, 2017 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28729032
19.
Targeted rescue of a polycystic kidney disease mutation by lysosomal inhibition.
Kidney Int
; 89(4): 949-55, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26924047
20.
Inhibition of histone deacetylase 6 activity reduces cyst growth in polycystic kidney disease.
Kidney Int
; 90(1): 90-9, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27165822