Detalhe da pesquisa
1.
Glucose transporter 4-deficient hearts develop maladaptive hypertrophy in response to physiological or pathological stresses.
Am J Physiol Heart Circ Physiol
; 313(6): H1098-H1108, 2017 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28822962
2.
Antioxidant treatment normalizes mitochondrial energetics and myocardial insulin sensitivity independently of changes in systemic metabolic homeostasis in a mouse model of the metabolic syndrome.
J Mol Cell Cardiol
; 85: 104-16, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-26004364
3.
PGC-1ß deficiency accelerates the transition to heart failure in pressure overload hypertrophy.
Circ Res
; 109(7): 783-93, 2011 Sep 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-21799152
4.
Genetic loss of insulin receptors worsens cardiac efficiency in diabetes.
J Mol Cell Cardiol
; 52(5): 1019-26, 2012 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-22342406
5.
A conserved role for phosphatidylinositol 3-kinase but not Akt signaling in mitochondrial adaptations that accompany physiological cardiac hypertrophy.
Cell Metab
; 6(4): 294-306, 2007 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-17908558
6.
Contribution of impaired myocardial insulin signaling to mitochondrial dysfunction and oxidative stress in the heart.
Circulation
; 119(9): 1272-83, 2009 Mar 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-19237663
7.
Impaired insulin signaling accelerates cardiac mitochondrial dysfunction after myocardial infarction.
J Mol Cell Cardiol
; 46(6): 910-8, 2009 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-19249310
8.
Insulin-like growth factor I receptor signaling is required for exercise-induced cardiac hypertrophy.
Mol Endocrinol
; 22(11): 2531-43, 2008 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-18801929
9.
Mechanistic target of rapamycin (Mtor) is essential for murine embryonic heart development and growth.
PLoS One
; 8(1): e54221, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23342106
10.
Type 1 diabetic akita mouse hearts are insulin sensitive but manifest structurally abnormal mitochondria that remain coupled despite increased uncoupling protein 3.
Diabetes
; 57(11): 2924-32, 2008 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-18678617