Detalhe da pesquisa
1.
The Role of Carbamoyl Phosphate Synthetase 1 as a Prognostic Biomarker in Patients With Acetaminophen-induced Acute Liver Failure.
Clin Gastroenterol Hepatol
; 21(12): 3060-3069.e8, 2023 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37054752
2.
Mutation of caspase-digestion sites in keratin 18 interferes with filament reorganization, and predisposes to hepatocyte necrosis and loss of membrane integrity.
J Cell Sci
; 127(Pt 7): 1464-75, 2014 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24463813
3.
Structural Requirements of Histone Deacetylase Inhibitors: SAHA Analogs Modified on the Hydroxamic Acid.
Arch Pharm (Weinheim)
; 349(5): 373-82, 2016 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-27062198
4.
Carbamoyl phosphate synthetase-1 is a rapid turnover biomarker in mouse and human acute liver injury.
Am J Physiol Gastrointest Liver Physiol
; 307(3): G355-64, 2014 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24924744
5.
CD73 (ecto-5'-nucleotidase) hepatocyte levels differ across mouse strains and contribute to mallory-denk body formation.
Hepatology
; 58(5): 1790-800, 2013 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-23729294
6.
Keratin hypersumoylation alters filament dynamics and is a marker for human liver disease and keratin mutation.
J Biol Chem
; 286(3): 2273-84, 2011 Jan 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-21062750
7.
Fibrinogen-γ proteolysis and solubility dynamics during apoptotic mouse liver injury: heparin prevents and treats liver damage.
Hepatology
; 53(4): 1323-32, 2011 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-21480334
8.
The structural requirements of histone deacetylase inhibitors: Suberoylanilide hydroxamic acid analogs modified at the C3 position display isoform selectivity.
Bioorg Med Chem Lett
; 21(20): 6139-42, 2011 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21889343
9.
A histone deacetylase-dependent screen in yeast.
Bioorg Med Chem
; 18(21): 7586-92, 2010 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20863708
10.
Synthesis and biological evaluation of histone deacetylase inhibitors that are based on FR235222: a cyclic tetrapeptide scaffold.
Bioorg Med Chem Lett
; 18(8): 2549-54, 2008 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18381239
11.
Mouse genetic background contributes to hepatocyte susceptibility to Fas-mediated apoptosis.
Mol Biol Cell
; 27(20): 3005-3012, 2016 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27535425
12.
Energy determinants GAPDH and NDPK act as genetic modifiers for hepatocyte inclusion formation.
J Cell Biol
; 195(2): 217-29, 2011 Oct 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-22006949
13.
Residues in the 11 A channel of histone deacetylase 1 promote catalytic activity: implications for designing isoform-selective histone deacetylase inhibitors.
J Med Chem
; 51(18): 5542-51, 2008 Sep 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-18729444
14.
Structural requirements of HDAC inhibitors: SAHA analogs functionalized adjacent to the hydroxamic acid.
Bioorg Med Chem Lett
; 17(8): 2216-9, 2007 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17307359