Detalhe da pesquisa
1.
CpG Island Hypermethylation Mediated by DNMT3A Is a Consequence of AML Progression.
Cell
; 168(5): 801-816.e13, 2017 02 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-28215704
2.
The origin and evolution of mutations in acute myeloid leukemia.
Cell
; 150(2): 264-78, 2012 Jul 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-22817890
3.
Retinoid X receptor promotes hematopoietic stem cell fitness and quiescence and preserves hematopoietic homeostasis.
Blood
; 141(6): 592-608, 2023 02 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36347014
4.
Molecular responses in decitabine- and decitabine/venetoclax-treated patients with acute myeloid leukemia and myelodysplastic syndromes.
Haematologica
; 2024 Apr 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38618679
5.
Immunosuppression and outcomes in adult patients with de novo acute myeloid leukemia with normal karyotypes.
Proc Natl Acad Sci U S A
; 118(49)2021 12 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34845035
6.
Cytokine exposure mediates transcriptional activation of the orphan nuclear receptor Nur77 in hematopoietic cells.
J Biol Chem
; 297(5): 101240, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34571009
7.
RXRA DT448/9PP generates a dominant active variant capable of inducing maturation in acute myeloid leukemia cells.
Haematologica
; 107(2): 417-426, 2022 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34134472
8.
An Isochroman Analog of CD3254 and Allyl-, Isochroman-Analogs of NEt-TMN Prove to Be More Potent Retinoid-X-Receptor (RXR) Selective Agonists Than Bexarotene.
Int J Mol Sci
; 23(24)2022 Dec 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-36555852
9.
Immune Escape of Relapsed AML Cells after Allogeneic Transplantation.
N Engl J Med
; 379(24): 2330-2341, 2018 12 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-30380364
10.
Mutation Clearance after Transplantation for Myelodysplastic Syndrome.
N Engl J Med
; 379(11): 1028-1041, 2018 Sep 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-30207916
11.
Endogenous and combination retinoids are active in myelomonocytic leukemias.
Haematologica
; 106(4): 1008-1021, 2021 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33241677
12.
Role of TP53 mutations in the origin and evolution of therapy-related acute myeloid leukaemia.
Nature
; 518(7540): 552-555, 2015 Feb 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-25487151
13.
Modeling, Synthesis, and Biological Evaluation of Potential Retinoid-X-Receptor (RXR) Selective Agonists: Analogs of 4-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahyro-2-naphthyl)ethynyl]benzoic Acid (Bexarotene) and 6-(Ethyl(4-isobutoxy-3-isopropylphenyl)amino)nicotinic Acid (NEt-4IB).
Int J Mol Sci
; 22(22)2021 Nov 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-34830251
14.
TP53 and Decitabine in Acute Myeloid Leukemia and Myelodysplastic Syndromes.
N Engl J Med
; 375(21): 2023-2036, 2016 11 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-27959731
15.
TP53 and the star-crossed lovers MDS and AML.
Blood
; 139(15): 2265-2266, 2022 04 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-35420690
16.
Mutational landscape and significance across 12 major cancer types.
Nature
; 502(7471): 333-339, 2013 Oct 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-24132290
17.
Rapid expansion of preexisting nonleukemic hematopoietic clones frequently follows induction therapy for de novo AML.
Blood
; 127(7): 893-7, 2016 Feb 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-26631115
18.
Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing.
Nature
; 481(7382): 506-10, 2012 Jan 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-22237025
19.
A sheep in wolf's clothing? Wild-type P53 disguises as mutant to promote leukemogenesis.
Haematologica
; 107(11): 2532-2533, 2022 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35199508
20.
Decitabine salvage for TP53-mutated, relapsed/refractory acute myeloid leukemia after cytotoxic induction therapy.
Haematologica
; 107(7): 1709-1713, 2022 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35236053