Detalhe da pesquisa
1.
Bcl-2 and IP3 compete for the ligand-binding domain of IP3Rs modulating Ca2+ signaling output.
Cell Mol Life Sci
; 76(19): 3843-3859, 2019 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-30989245
2.
Resveratrol-induced autophagy is dependent on IP3Rs and on cytosolic Ca2.
Biochim Biophys Acta Mol Cell Res
; 1864(6): 947-956, 2017 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-28254579
3.
Nutrient Starvation Decreases Cx43 Levels and Limits Intercellular Communication in Primary Bovine Corneal Endothelial Cells.
J Membr Biol
; 249(3): 363-73, 2016 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-26873723
4.
Regulation of the ryanodine receptor by anti-apoptotic Bcl-2 is independent of its BH3-domain-binding properties.
Biochem Biophys Res Commun
; 463(3): 174-9, 2015 Jul 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-25957473
5.
Polycystin-1 but not polycystin-2 deficiency causes upregulation of the mTOR pathway and can be synergistically targeted with rapamycin and metformin.
Pflugers Arch
; 466(8): 1591-604, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24193408
6.
LRRK2 phosphorylation status and kinase activity regulate (macro)autophagy in a Rab8a/Rab10-dependent manner.
Cell Death Dis
; 14(7): 436, 2023 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37454104
7.
Intracellular BAPTA directly inhibits PFKFB3, thereby impeding mTORC1-driven Mcl-1 translation and killing MCL-1-addicted cancer cells.
Cell Death Dis
; 14(9): 600, 2023 09 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37684238
8.
Disrupted Ca2+ homeostasis and immunodeficiency in patients with functional IP3 receptor subtype 3 defects.
Cell Mol Immunol
; 20(1): 11-25, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36302985
9.
Bcl-xL acts as an inhibitor of IP3R channels, thereby antagonizing Ca2+-driven apoptosis.
Cell Death Differ
; 29(4): 788-805, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34750538
10.
Constitutive IP3 signaling underlies the sensitivity of B-cell cancers to the Bcl-2/IP3 receptor disruptor BIRD-2.
Cell Death Differ
; 26(3): 531-547, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29899382
11.
HA14-1, but not the BH3 mimetic ABT-737, causes Ca2+ dysregulation in platelets and human cell lines.
Haematologica
; 98(4): e49-51, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-23403318
12.
The ER Stress Inducer l-Azetidine-2-Carboxylic Acid Elevates the Levels of Phospho-eIF2α and of LC3-II in a Ca2+-Dependent Manner.
Cells
; 7(12)2018 Nov 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-30513588
13.
A double point mutation at residues Ile14 and Val15 of Bcl-2 uncovers a role for the BH4 domain in both protein stability and function.
FEBS J
; 285(1): 127-145, 2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29131545
14.
Author Correction: Disrupted Ca2+ homeostasis and immunodeficiency in patients with functional IP3 receptor subtype 3 defects.
Cell Mol Immunol
; 20(1): 114, 2023 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-36471115
15.
Basal ryanodine receptor activity suppresses autophagic flux.
Biochem Pharmacol
; 132: 133-142, 2017 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28322744
16.
The trans-membrane domain of Bcl-2α, but not its hydrophobic cleft, is a critical determinant for efficient IP3 receptor inhibition.
Oncotarget
; 7(34): 55704-55720, 2016 Aug 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-27494888
17.
mTOR-Controlled Autophagy Requires Intracellular Ca(2+) Signaling.
PLoS One
; 8(4): e61020, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23565295
18.
Bax Inhibitor-1-mediated Ca2+ leak is decreased by cytosolic acidosis.
Cell Calcium
; 54(3): 186-92, 2013 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-23867001
19.
Ins(1,4,5)P3 receptor-mediated Ca2+ signaling and autophagy induction are interrelated.
Autophagy
; 7(12): 1472-89, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-22082873