Detalhe da pesquisa
1.
Maternal diet modulates the infant microbiome and intestinal Flt3L necessary for dendritic cell development and immunity to respiratory infection.
Immunity
; 56(5): 1098-1114.e10, 2023 05 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37003256
2.
Actionable Cytopathogenic Host Responses of Human Alveolar Type 2 Cells to SARS-CoV-2.
Mol Cell
; 80(6): 1104-1122.e9, 2020 12 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-33259812
3.
The COPD GWAS gene ADGRG6 instructs function and injury response in human iPSC-derived type II alveolar epithelial cells.
Am J Hum Genet
; 110(10): 1735-1749, 2023 10 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37734371
4.
Actionable Cytopathogenic Host Responses of Human Alveolar Type 2 Cells to SARS-CoV-2.
Mol Cell
; 81(1): 212, 2021 Jan 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33417854
5.
Targeting the P2Y13 Receptor Suppresses IL-33 and HMGB1 Release and Ameliorates Experimental Asthma.
Am J Respir Crit Care Med
; 205(3): 300-312, 2022 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34860143
6.
Human airway lineages derived from pluripotent stem cells reveal the epithelial responses to SARS-CoV-2 infection.
Am J Physiol Lung Cell Mol Physiol
; 322(3): L462-L478, 2022 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35020534
7.
HMGB1 amplifies ILC2-induced type-2 inflammation and airway smooth muscle remodelling.
PLoS Pathog
; 16(7): e1008651, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32658914
8.
Adenine base editing reduces misfolded protein accumulation and toxicity in alpha-1 antitrypsin deficient patient iPSC-hepatocytes.
Mol Ther
; 29(11): 3219-3229, 2021 11 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34217893
9.
Respiratory Syncytial Virus Infection Promotes Necroptosis and HMGB1 Release by Airway Epithelial Cells.
Am J Respir Crit Care Med
; 201(11): 1358-1371, 2020 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32105156
10.
Chronic IL-33 expression predisposes to virus-induced asthma exacerbations by increasing type 2 inflammation and dampening antiviral immunity.
J Allergy Clin Immunol
; 141(5): 1607-1619.e9, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28947081
11.
Gene-based analysis of regulatory variants identifies 4 putative novel asthma risk genes related to nucleotide synthesis and signaling.
J Allergy Clin Immunol
; 139(4): 1148-1157, 2017 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-27554816
12.
Aeroallergen-induced IL-33 predisposes to respiratory virus-induced asthma by dampening antiviral immunity.
J Allergy Clin Immunol
; 138(5): 1326-1337, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27236500
13.
IRF-3, IRF-7, and IPS-1 promote host defense against acute human metapneumovirus infection in neonatal mice.
Am J Pathol
; 184(6): 1795-806, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24726644
14.
Identification of a distal enhancer regulating hedgehog interacting protein gene in human lung epithelial cells.
EBioMedicine
; 101: 105026, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38417378
15.
Generating 3D Spheres and 2D Air-Liquid Interface Cultures of Human Induced Pluripotent Stem Cell-Derived Type 2 Alveolar Epithelial Cells.
J Vis Exp
; (182)2022 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35499347
16.
Air-liquid interface culture promotes maturation and allows environmental exposure of pluripotent stem cell-derived alveolar epithelium.
JCI Insight
; 7(6)2022 03 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-35315362
17.
CRISPR interference interrogation of COPD GWAS genes reveals the functional significance of desmoplakin in iPSC-derived alveolar epithelial cells.
Sci Adv
; 8(28): eabo6566, 2022 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35857525
18.
Human iPSC-hepatocyte modeling of alpha-1 antitrypsin heterozygosity reveals metabolic dysregulation and cellular heterogeneity.
Cell Rep
; 41(10): 111775, 2022 12 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36476855
19.
Characterization of the COPD alveolar niche using single-cell RNA sequencing.
Nat Commun
; 13(1): 494, 2022 01 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-35078977
20.
The oral drug nitazoxanide restricts SARS-CoV-2 infection and attenuates disease pathogenesis in Syrian hamsters.
bioRxiv
; 2022 Feb 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35169796