Detalhe da pesquisa
1.
Intestinal Metabolism and Bioaccumulation of Sucralose In Adipose Tissue In The Rat.
J Toxicol Environ Health A
; 81(18): 913-923, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30130461
2.
Subtype-selective Na(v)1.8 sodium channel blockers: identification of potent, orally active nicotinamide derivatives.
Bioorg Med Chem Lett
; 20(22): 6812-5, 2010 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20855211
3.
Discovery and biological evaluation of potent, selective, orally bioavailable, pyrazine-based blockers of the Na(v)1.8 sodium channel with efficacy in a model of neuropathic pain.
Bioorg Med Chem
; 18(22): 7816-25, 2010 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20965738
4.
In vivo profile of ICA-27243 [N-(6-chloro-pyridin-3-yl)-3,4-difluoro-benzamide], a potent and selective KCNQ2/Q3 (Kv7.2/Kv7.3) activator in rodent anticonvulsant models.
J Pharmacol Exp Ther
; 326(3): 818-28, 2008 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-18577704
5.
Discovery and biological evaluation of 5-aryl-2-furfuramides, potent and selective blockers of the Nav1.8 sodium channel with efficacy in models of neuropathic and inflammatory pain.
J Med Chem
; 51(3): 407-16, 2008 Feb 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-18176998
6.
Discovery of potent furan piperazine sodium channel blockers for treatment of neuropathic pain.
Bioorg Med Chem
; 16(12): 6379-86, 2008 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18501613