Detalhe da pesquisa
1.
Activity of Oral ALS-008176 in a Respiratory Syncytial Virus Challenge Study.
N Engl J Med
; 373(21): 2048-58, 2015 Nov 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-26580997
2.
Pharmacokinetics, safety and tolerability of single- and multiple-ascending doses of JNJ-64530440, a novel hepatitis B virus capsid assembly modulator, in healthy volunteers.
Antivir Ther
; 26(1-2): 13-24, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-35485346
3.
Population Pharmacokinetics of AL-335 and Its Two Main Metabolites (ALS-022399, ALS-022227) in Monotherapy and in Combination with Odalasvir and/or Simeprevir.
AAPS J
; 21(1): 1, 2018 10 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-30377854
4.
Characterizing the Pharmacokinetic Interaction Between Simeprevir and Odalasvir in Healthy Volunteers Using a Population Modeling Approach.
AAPS J
; 20(6): 111, 2018 10 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-30350297
5.
Safety, tolerability, and pharmacokinetics of AL-335 in healthy volunteers and hepatitis C virus-infected subjects.
PLoS One
; 13(10): e0204974, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30325939
6.
Pharmacokinetics, safety, and tolerability of the 2- and 3-direct-acting antiviral combination of AL-335, odalasvir, and simeprevir in healthy subjects.
Pharmacol Res Perspect
; 6(3): e00395, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29736243
7.
In vitro antiviral susceptibility of full-length clinical hepatitis B virus isolates cloned with a novel expression vector.
Antiviral Res
; 61(1): 27-36, 2004 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-14670591
8.
Elotuzumab in combination with lenalidomide and low-dose dexamethasone in relapsed or refractory multiple myeloma.
J Clin Oncol
; 30(16): 1953-9, 2012 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22547589
9.
Week 48 resistance surveillance in two phase 3 clinical studies of adefovir dipivoxil for chronic hepatitis B.
Hepatology
; 38(1): 96-103, 2003 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-12829991
10.
The hepatitis B virus polymerase mutation rtV173L is selected during lamivudine therapy and enhances viral replication in vitro.
J Virol
; 77(21): 11833-41, 2003 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-14557667
11.
Resistance surveillance in chronic hepatitis B patients treated with adefovir dipivoxil for up to 60 weeks.
Hepatology
; 36(2): 464-73, 2002 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-12143057
12.
Selection of a hepatitis B virus strain resistant to adefovir in a liver transplantation patient.
J Hepatol
; 39(6): 1085-9, 2003 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-14642631
13.
Adefovir dipivoxil therapy for lamivudine-resistant hepatitis B in pre- and post-liver transplantation patients.
Hepatology
; 38(6): 1419-27, 2003 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-14647053