Detalhe da pesquisa
1.
A secreted tyrosine kinase acts in the extracellular environment.
Cell
; 158(5): 1033-1044, 2014 Aug 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-25171405
2.
The secreted tyrosine kinase VLK is essential for normal platelet activation and thrombus formation.
Blood
; 139(1): 104-117, 2022 01 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34329392
3.
Aminoacyl-tRNA synthetase inhibition activates a pathway that branches from the canonical amino acid response in mammalian cells.
Proc Natl Acad Sci U S A
; 117(16): 8900-8911, 2020 04 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32253314
4.
Halofuginone and other febrifugine derivatives inhibit prolyl-tRNA synthetase.
Nat Chem Biol
; 8(3): 311-7, 2012 Feb 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-22327401
5.
Small ubiquitin-like modifier (SUMO) modification mediates function of the inhibitory domains of developmental regulators FOXC1 and FOXC2.
J Biol Chem
; 287(22): 18318-29, 2012 May 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-22493429
6.
A mutation in TGFB3 associated with a syndrome of low muscle mass, growth retardation, distal arthrogryposis and clinical features overlapping with Marfan and Loeys-Dietz syndrome.
Am J Med Genet A
; 161A(8): 2040-6, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23824657
7.
Loss of Vlk in Prx1+ Cells Delays the Initial Steps of Endochondral Bone Formation and Fracture Repair in the Limb.
J Bone Miner Res
; 37(4): 764-775, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35080046
8.
Elucidating the path to Plasmodium prolyl-tRNA synthetase inhibitors that overcome halofuginone resistance.
Nat Commun
; 13(1): 4976, 2022 08 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-36008486
9.
Oxidative stress drives disulfide bond formation between basic helix-loop-helix transcription factors.
J Cell Biochem
; 109(2): 417-24, 2010 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19950203
10.
TGF-beta signaling is required for multiple processes during Xenopus tail regeneration.
Dev Biol
; 315(1): 203-16, 2008 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18234181
11.
TRIQK, a novel family of small proteins localized to the endoplasmic reticulum membrane, is conserved across vertebrates.
Zoolog Sci
; 25(7): 706-13, 2008 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-18828657
12.
A Serpin family gene, protease nexin-1 has an activity distinct from protease inhibition in early Xenopus embryos.
Mech Dev
; 123(6): 463-71, 2006 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-16797167
13.
Halofuginone treatment reduces interleukin-17A and ameliorates features of chronic lung allograft dysfunction in a mouse orthotopic lung transplant model.
J Heart Lung Transplant
; 35(4): 518-27, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26787621
14.
Premature Termination Codons Are Recognized in the Nucleus in A Reading-Frame Dependent Manner.
Cell Discov
; 12015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26491543
15.
Evidence for cadherin-11 cleavage in the synovium and partial characterization of its mechanism.
Arthritis Res Ther
; 17: 126, 2015 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25975695
16.
The cytoplasmic prolyl-tRNA synthetase of the malaria parasite is a dual-stage target of febrifugine and its analogs.
Sci Transl Med
; 7(288): 288ra77, 2015 May 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-25995223
17.
Microarray profiling reveals the integrated stress response is activated by halofuginone in mammary epithelial cells.
BMC Res Notes
; 4: 381, 2011 Oct 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-21974968
18.
The role and regulation of GDF11 in Smad2 activation during tailbud formation in the Xenopus embryo.
Mech Dev
; 127(9-12): 485-95, 2010.
Artigo
em Inglês
| MEDLINE | ID: mdl-20807570
19.
Halofuginone inhibits TH17 cell differentiation by activating the amino acid starvation response.
Science
; 324(5932): 1334-8, 2009 Jun 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-19498172
20.
Identification of a novel pool of extracellular pro-myostatin in skeletal muscle.
J Biol Chem
; 283(11): 7027-35, 2008 Mar 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-18175804