Detalhe da pesquisa
1.
A trispecific antibody targeting HER2 and T cells inhibits breast cancer growth via CD4 cells.
Nature
; 603(7900): 328-334, 2022 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-35197632
2.
ICOS agonist vopratelimab modulates follicular helper T cells and improves B cell function in common variable immunodeficiency.
Clin Immunol
; 264: 110217, 2024 Apr 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38621471
3.
SAR442085, a novel anti-CD38 antibody with enhanced antitumor activity against multiple myeloma.
Blood
; 139(8): 1160-1176, 2022 02 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-35201323
4.
Publisher Correction: A trispecific antibody targeting HER2 and T cells inhibits breast cancer growth via CD4 cells.
Nature
; 604(7905): E13, 2022 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-35332336
5.
Identification of the endosomal sorting complex required for transport-I (ESCRT-I) as an important modulator of anti-miR uptake by cancer cells.
Nucleic Acids Res
; 43(2): 1204-15, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25550434
6.
Selective inhibition of mutant isocitrate dehydrogenase 1 (IDH1) via disruption of a metal binding network by an allosteric small molecule.
J Biol Chem
; 290(2): 762-74, 2015 Jan 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-25391653
7.
PIM inhibitors target CD25-positive AML cells through concomitant suppression of STAT5 activation and degradation of MYC oncogene.
Blood
; 124(11): 1777-89, 2014 Sep 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-25006129
8.
Evaluation of cancer dependence and druggability of PRP4 kinase using cellular, biochemical, and structural approaches.
J Biol Chem
; 288(42): 30125-30138, 2013 Oct 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-24003220
9.
Inhibition of LILRB2 by a Novel Blocking Antibody Designed to Reprogram Immunosuppressive Macrophages to Drive T-Cell Activation in Tumors.
Mol Cancer Ther
; 22(4): 471-484, 2023 04 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36780212
10.
BND-22, a first-in-class humanized ILT2-blocking antibody, promotes antitumor immunity and tumor regression.
J Immunother Cancer
; 10(9)2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36096532
11.
Differential expression of CCR8 in tumors versus normal tissue allows specific depletion of tumor-infiltrating T regulatory cells by GS-1811, a novel Fc-optimized anti-CCR8 antibody.
Oncoimmunology
; 11(1): 2141007, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36352891
12.
PTEN-deficient cancers depend on PIK3CB.
Proc Natl Acad Sci U S A
; 105(35): 13057-62, 2008 Sep 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-18755892
13.
An experimental model of anti-PD-1 resistance exhibits activation of TGFß and Notch pathways and is sensitive to local mRNA immunotherapy.
Oncoimmunology
; 10(1): 1881268, 2021 03 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33796402
14.
Pre-clinical development of a novel CD3-CD123 bispecific T-cell engager using cross-over dual-variable domain (CODV) format for acute myeloid leukemia (AML) treatment.
Oncoimmunology
; 10(1): 1945803, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34484869
15.
Local delivery of mRNA-encoded cytokines promotes antitumor immunity and tumor eradication across multiple preclinical tumor models.
Sci Transl Med
; 13(610): eabc7804, 2021 Sep 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34516826
16.
Contribution of polycomb homologues Bmi-1 and Mel-18 to medulloblastoma pathogenesis.
Mol Cell Biol
; 27(13): 4968-79, 2007 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-17452456
17.
Pan-TGFß inhibition by SAR439459 relieves immunosuppression and improves antitumor efficacy of PD-1 blockade.
Oncoimmunology
; 9(1): 1811605, 2020 09 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-33224628
18.
Isatuximab Acts Through Fc-Dependent, Independent, and Direct Pathways to Kill Multiple Myeloma Cells.
Front Immunol
; 11: 1771, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32922390
19.
An iron-dependent metabolic vulnerability underlies VPS34-dependence in RKO cancer cells.
PLoS One
; 15(8): e0235551, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32833964
20.
Tumor-specific urinary matrix metalloproteinase fingerprinting: identification of high molecular weight urinary matrix metalloproteinase species.
Clin Cancer Res
; 14(20): 6610-7, 2008 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18927302